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GENE CARD

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Gene Card

Best human hits

C8B; LRP6

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00012345

Gene Model ID

KH2012:KH.L34.6

Location

KhL34:93627..94917

Transcript Models and Sequences

  KH2012:KH.L34.6.v1.C.nonSL10-1
KH2012:KH.L34.6.v1.C.nonSL11-1
KH2012:KH.L34.6.v1.C.nonSL12-1
KH2012:KH.L34.6.v1.C.nonSL13-1
KH2012:KH.L34.6.v1.C.nonSL14-1
KH2012:KH.L34.6.v1.C.nonSL15-1
KH2012:KH.L34.6.v1.C.nonSL16-1
KH2012:KH.L34.6.v1.C.nonSL17-1
KH2012:KH.L34.6.v1.C.nonSL18-1
KH2012:KH.L34.6.v1.C.nonSL20-1
KH2012:KH.L34.6.v1.C.nonSL21-1
KH2012:KH.L34.6.v1.C.nonSL22-1
KH2012:KH.L34.6.v1.C.nonSL3-1
KH2012:KH.L34.6.v1.C.nonSL4-1
KH2012:KH.L34.6.v1.C.nonSL5-1
KH2012:KH.L34.6.v1.C.nonSL7-1
KH2012:KH.L34.6.v1.C.nonSL8-1
KH2012:KH.L34.6.v1.C.SL1-1
KH2012:KH.L34.6.v1.C.SL19-1
KH2012:KH.L34.6.v1.C.SL2-1
KH2012:KH.L34.6.v1.C.SL6-1
KH2012:KH.L34.6.v1.C.SL9-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000004002
ENSEMBL ENSCING00000021120
Collections

Gateway full ORF

2 results

cima885002

Plate: VES69_P15

cima890524

Plate: VES70_B17

Gene collection 1 (N. Satoh)

2 results

cieg036d03

Plate: R1CiGC21e04

cigd037b09

Plate: R1CiGC41f07

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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No Phylogeny Tree for this Gene.
Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
LDL_receptor-like_sf SUPERFAMILY LDL receptor-like superfamily
LDrepeatLR_classA_rpt SMART Low-density lipoprotein (LDL) receptor class A repeat
LDLR_class-A_CS ProSitePatterns Low-density lipoprotein (LDL) receptor class A, conserved site
LDrepeatLR_classA_rpt Pfam Low-density lipoprotein (LDL) receptor class A repeat
LDrepeatLR_classA_rpt CDD Low-density lipoprotein (LDL) receptor class A repeat
LDrepeatLR_classA_rpt ProSiteProfiles Low-density lipoprotein (LDL) receptor class A repeat

GOSlim

36 results

GO Term Annotation Origin Type
receptor binding Blast molecular function
protein binding Blast molecular function
extracellular region Blast cellular component
extracellular space Blast cellular component
early endosome Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
plasma membrane Blast cellular component
cell surface Blast cellular component
membrane Blast cellular component
integral component of membrane Blast cellular component
cytoplasmic vesicle Blast cellular component
identical protein binding Blast molecular function
protein homodimerization activity Blast molecular function
neuronal cell body Blast cellular component
membrane raft Blast cellular component
synapse Blast cellular component
extracellular exosome Blast cellular component
extracellular vesicle Blast cellular component
membrane organization Blast biological process
organelle organization Blast biological process
macromolecular complex binding Blast molecular function
integral component of plasma membrane Blast cellular component
macromolecular complex Blast cellular component
plasma membrane region Blast cellular component
kinase activity Blast molecular function
enzyme regulator activity Blast molecular function
transmembrane transport Blast biological process
whole membrane Blast cellular component
intracellular organelle part Blast cellular component
bounding membrane of organelle Blast cellular component
cell surface receptor signaling pathway Blast biological process
cell-cell signaling Blast biological process
transmembrane signaling receptor activity Blast molecular function
signaling receptor activity Blast molecular function
plasma membrane part Blast cellular component

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type

GO (Blast)

34 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
low-density lipoprotein receptor activity Hs molecular function 43.1 5.22e-05
receptor binding Hs molecular function 43.1 5.22e-05
frizzled binding Hs molecular function 43.1 5.22e-05
protein binding Hs molecular function 46.2 5.02e-06
extracellular region Hs cellular component 46.2 5.02e-06
membrane attack complex Hs cellular component 46.2 5.02e-06
extracellular space Hs cellular component 46.2 5.02e-06
early endosome Hs cellular component 43.1 5.22e-05
endoplasmic reticulum Hs cellular component 43.1 5.22e-05
Golgi apparatus Hs cellular component 43.1 5.22e-05
plasma membrane Hs cellular component 43.1 5.22e-05
caveola Hs cellular component 43.1 5.22e-05
cell surface Hs cellular component 43.1 5.22e-05
membrane Hs cellular component 46.2 5.02e-06
integral component of membrane Hs cellular component 43.1 5.22e-05
Wnt-protein binding Hs molecular function 43.1 5.22e-05
kinase inhibitor activity Hs molecular function 43.1 5.22e-05
toxin transporter activity Hs molecular function 43.1 5.22e-05
cytoplasmic vesicle Hs cellular component 43.1 5.22e-05
early endosome membrane Hs cellular component 43.1 5.22e-05
apolipoprotein binding Hs molecular function 43.1 5.22e-05
identical protein binding Hs molecular function 43.1 5.22e-05
protein homodimerization activity Hs molecular function 43.1 5.22e-05
Wnt-activated receptor activity Hs molecular function 43.1 5.22e-05
neuronal cell body Hs cellular component 43.1 5.22e-05
receptor complex Hs cellular component 43.1 5.22e-05
membrane raft Hs cellular component 43.1 5.22e-05
synapse Hs cellular component 43.1 5.22e-05
extracellular exosome Hs cellular component 46.2 5.02e-06
coreceptor activity involved in Wnt signaling pathway Hs molecular function 43.1 5.22e-05
extracellular vesicle Hs cellular component 46.2 5.02e-06
coreceptor activity involved in canonical Wnt signaling pathway Hs molecular function 43.1 5.22e-05
Wnt-Frizzled-LRP5/6 complex Hs cellular component 43.1 5.22e-05
Wnt signalosome Hs cellular component 43.1 5.22e-05

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding SUPERFAMILY molecular function 4.71E-8

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