Gene Card
Best human hits
EPS8; EPS8L1; EPS8L2
Unique Gene ID
Cirobu.g00012280
Gene Model ID
KH2012:KH.L3.10
Location
KhL3:183121..196919
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000002732 |
ENSEMBL | ENSCING00000022196 |
cinc023a13
Plate: R1CiGC45e08
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PTB/PI_dom | ProSiteProfiles | PTB/PI domain |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
SH3_domain | Pfam | SH3 domain |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
PTB | Pfam | Tensin/EPS8 phosphotyrosine-binding domain |
SH3_domain | ProSiteProfiles | SH3 domain |
PTB/PI_dom | SMART | PTB/PI domain |
SH3_domain | SMART | SH3 domain |
EPS8_PTB | CDD | Epidermal growth factor receptor kinase substrate, phosphotyrosine-binding domain |
EPS8 | PANTHER | Epidermal growth factor receptor kinase substrate 8 |
GO Term | Annotation Origin | Type |
---|---|---|
actin binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
brush border | Orthology | cellular component |
signal transduction | Orthology | biological process |
sensory perception of sound | Orthology | biological process |
cell proliferation | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
cell junction | Orthology | cellular component |
vesicle | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
cell projection | Orthology | cellular component |
neuron projection | Orthology | cellular component |
synapse | Orthology | cellular component |
regulation of molecular function | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
cell periphery | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
cell morphogenesis | Orthology | biological process |
mitotic cell cycle phase transition | Orthology | biological process |
organelle | Orthology | cellular component |
postsynapse | Orthology | cellular component |
neuron part | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
cell projection part | Orthology | cellular component |
axon | Orthology | cellular component |
organelle organization | Orthology | biological process |
cluster of actin-based cell projections | Orthology | cellular component |
cell projection membrane | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
regulation of signal transduction | Orthology | biological process |
receptor binding | Orthology | molecular function |
macromolecular complex binding | Orthology | molecular function |
cell adhesion molecule binding | Orthology | molecular function |
response to organic substance | Orthology | biological process |
cell projection assembly | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
actin binding | Hs | molecular function |
SH3/SH2 adaptor activity | Hs | molecular function |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
brush border | Hs | cellular component |
cell cortex | Hs | cellular component |
signal transduction | Hs | biological process |
epidermal growth factor receptor signaling pathway | Hs | biological process |
Rho protein signal transduction | Hs | biological process |
sensory perception of sound | Hs | biological process |
cell proliferation | Hs | biological process |
adult locomotory behavior | Hs | biological process |
regulation of cell shape | Hs | biological process |
positive regulation of signal transduction | Hs | biological process |
exit from mitosis | Hs | biological process |
postsynaptic density | Hs | cellular component |
membrane | Hs | cellular component |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
Rac protein signal transduction | Hs | biological process |
NMDA selective glutamate receptor complex | Hs | cellular component |
cell junction | Hs | cellular component |
growth cone | Hs | cellular component |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function |
actin cytoskeleton reorganization | Hs | biological process |
vesicle | Hs | cellular component |
stereocilium | Hs | cellular component |
stereocilium bundle | Hs | cellular component |
stereocilium tip | Hs | cellular component |
ruffle membrane | Hs | cellular component |
macromolecular complex | Hs | cellular component |
regulation of Rho protein signal transduction | Hs | biological process |
signaling adaptor activity | Hs | molecular function |
T cell receptor binding | Hs | molecular function |
cell projection | Hs | cellular component |
neuron projection | Hs | cellular component |
synapse | Hs | cellular component |
cadherin binding | Hs | molecular function |
behavioral response to ethanol | Hs | biological process |
Rac GTPase binding | Hs | molecular function |
barbed-end actin filament capping | Hs | biological process |
actin filament bundle assembly | Hs | biological process |
actin crosslink formation | Hs | biological process |
regulation of molecular function | Hs | biological process |
extracellular exosome | Hs | cellular component |
positive regulation of ruffle assembly | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
actin binding | Hs | molecular function | 441 | 4.10e-143 |
SH3/SH2 adaptor activity | Hs | molecular function | 441 | 4.10e-143 |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function | 393 | 9.43e-126 |
protein binding | Hs | molecular function | 441 | 4.10e-143 |
cytoplasm | Hs | cellular component | 441 | 4.10e-143 |
cytosol | Hs | cellular component | 393 | 9.43e-126 |
plasma membrane | Hs | cellular component | 441 | 4.10e-143 |
brush border | Hs | cellular component | 441 | 4.10e-143 |
cell cortex | Hs | cellular component | 441 | 4.10e-143 |
postsynaptic density | Hs | cellular component | 441 | 4.10e-143 |
membrane | Hs | cellular component | 441 | 4.10e-143 |
kinase activity | Hs | molecular function | 282 | 4.15e-84 |
NMDA selective glutamate receptor complex | Hs | cellular component | 441 | 4.10e-143 |
cell junction | Hs | cellular component | 441 | 4.10e-143 |
growth cone | Hs | cellular component | 441 | 4.10e-143 |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function | 393 | 9.43e-126 |
vesicle | Hs | cellular component | 441 | 4.10e-143 |
stereocilium | Hs | cellular component | 441 | 4.10e-143 |
stereocilium bundle | Hs | cellular component | 441 | 4.10e-143 |
stereocilium tip | Hs | cellular component | 441 | 4.10e-143 |
ruffle membrane | Hs | cellular component | 441 | 4.10e-143 |
macromolecular complex | Hs | cellular component | 393 | 9.43e-126 |
signaling adaptor activity | Hs | molecular function | 441 | 4.10e-143 |
T cell receptor binding | Hs | molecular function | 282 | 4.15e-84 |
cell projection | Hs | cellular component | 441 | 4.10e-143 |
neuron projection | Hs | cellular component | 441 | 4.10e-143 |
synapse | Hs | cellular component | 441 | 4.10e-143 |
cadherin binding | Hs | molecular function | 393 | 9.43e-126 |
Rac GTPase binding | Hs | molecular function | 441 | 4.10e-143 |
extracellular exosome | Hs | cellular component | 441 | 4.10e-143 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
actin binding | PANTHER | molecular function | 5.6E-102 |
protein binding | Pfam | molecular function | 3.7E-42 |
signaling adaptor activity | PANTHER | molecular function | 5.6E-102 |
barbed-end actin filament capping | PANTHER | biological process | 5.6E-102 |
actin filament bundle assembly | PANTHER | biological process | 5.6E-102 |