Aniseed - Gene card

Gene Card

Best human hits

MLH1; PMS1; PMS2

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00011891

Gene Model ID

KH2012:KH.L172.8

Location

KhL172:38479..44375

Transcript Models and Sequences

KH2012:KH.L172.8.v1.A.nonSL3-1
KH2012:KH.L172.8.v1.A.nonSL4-1
KH2012:KH.L172.8.v1.A.nonSL5-1
KH2012:KH.L172.8.v1.A.nonSL6-1
KH2012:KH.L172.8.v1.A.nonSL7-1
KH2012:KH.L172.8.v1.A.nonSL8-1
KH2012:KH.L172.8.v1.A.SL2-1
KH2012:KH.L172.8.v2.A.SL1-1

External Database Gene Card

External database links

4 results

Database	Gene ID
ENSEMBL	ENSCING00000002674
ENSEMBL	ENSCING00000018539
NCBI Reference Sequence	XM_002120374.1
NCBI Reference Sequence	XM_018815619.1

Collections

Gateway full ORF

4 results

Gene collection 1 (N. Satoh)

1 result

cicl045c19

Plate: R1CiGC13g05

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term	Analysis	Definition
ERV/ALR_sulphydryl_oxidase	Pfam	ERV/ALR sulfhydryl oxidase domain
ERV/ALR_sulphydryl_oxidase	ProSiteProfiles	ERV/ALR sulfhydryl oxidase domain
ERV/ALR_sulphydryl_oxid_sf	Gene3D	ERV/ALR sulfhydryl oxidase domain superfamily
ERV/ALR_sulphydryl_oxid_sf	SUPERFAMILY	ERV/ALR sulfhydryl oxidase domain superfamily
HATPase_C_sf	Gene3D	Histidine kinase/HSP90-like ATPase superfamily
DNA_mismatch_repair_CS	ProSitePatterns	DNA mismatch repair, conserved site
DNA_mismatch_repair_C	Pfam	DNA mismatch repair protein, C-terminal
DNA_mismatch_repair_fam	TIGRFAM	DNA mismatch repair protein family
DNA_mismatch_repair_C	SMART	DNA mismatch repair protein, C-terminal
HATPase_C_sf	SUPERFAMILY	Histidine kinase/HSP90-like ATPase superfamily
MutL_C	SMART	MutL, C-terminal, dimerisation
HATPase_C	CDD	Histidine kinase/HSP90-like ATPase
Ribosomal_S5_D2-typ_fold	SUPERFAMILY	Ribosomal protein S5 domain 2-type fold
MutL_C_sf	SUPERFAMILY	MutL, C-terminal domain superfamily
Ribosomal_S5_D2-typ_fold_subgr	Gene3D	Ribosomal protein S5 domain 2-type fold, subgroup
MutL_C	Pfam	MutL, C-terminal, dimerisation

GOSlim

27 results

GO Term	Annotation Origin	Type
nucleotide binding	Blast	molecular function
DNA binding	Orthology	molecular function
chromatin binding	Blast	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
DNA repair	Orthology	biological process
cellular response to DNA damage stimulus	Orthology	biological process
microtubule cytoskeleton	Orthology	cellular component
membrane	Blast	cellular component
hydrolase activity	Orthology	molecular function
oxidation-reduction process	InterProScan	biological process
system development	Orthology	biological process
immune system process	Orthology	biological process
nucleoside-triphosphatase activity	Orthology	molecular function
double-stranded DNA binding	Orthology	molecular function
nuclear part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
macromolecular complex binding	Orthology	molecular function
cytoplasmic part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Blast	cellular component
intracellular part	Blast	cellular component
catalytic activity	InterProScan	molecular function

GO (Orthology)

24 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
DNA binding	Hs	molecular function
single-stranded DNA binding	Hs	molecular function
nuclease activity	Hs	molecular function
endonuclease activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
DNA repair	Hs	biological process
mismatch repair	Hs	biological process
cellular response to DNA damage stimulus	Hs	biological process
microtubule cytoskeleton	Hs	cellular component
somatic hypermutation of immunoglobulin genes	Hs	biological process
hydrolase activity	Hs	molecular function
ATPase activity	Hs	molecular function
mismatched DNA binding	Hs	molecular function
single base insertion or deletion binding	Hs	molecular function
MutLalpha complex	Hs	cellular component
MutSalpha complex binding	Hs	molecular function
cytoplasmic ribonucleoprotein granule	Hs	cellular component
response to drug	Hs	biological process
nucleic acid phosphodiester bond hydrolysis	Hs	biological process

GO (Blast)

30 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	156	2.62e-39
condensed chromosome	Hs	cellular component	156	2.62e-39
condensed nuclear chromosome	Hs	cellular component	156	2.62e-39
synaptonemal complex	Hs	cellular component	156	2.62e-39
male germ cell nucleus	Hs	cellular component	156	2.62e-39
DNA binding	Hs	molecular function	396	3.94e-125
chromatin binding	Hs	molecular function	156	2.62e-39
single-stranded DNA binding	Hs	molecular function	396	3.94e-125
nuclease activity	Hs	molecular function	396	3.94e-125
endonuclease activity	Hs	molecular function	396	3.94e-125
protein binding	Hs	molecular function	396	3.94e-125
ATP binding	Hs	molecular function	396	3.94e-125
nucleus	Hs	cellular component	396	3.94e-125
nucleoplasm	Hs	cellular component	396	3.94e-125
chromosome	Hs	cellular component	156	2.62e-39
chiasma	Hs	cellular component	156	2.62e-39
late recombination nodule	Hs	cellular component	156	2.62e-39
cytosol	Hs	cellular component	396	3.94e-125
plasma membrane	Hs	cellular component	396	3.94e-125
microtubule cytoskeleton	Hs	cellular component	396	3.94e-125
membrane	Hs	cellular component	156	2.62e-39
hydrolase activity	Hs	molecular function	396	3.94e-125
ATPase activity	Hs	molecular function	396	3.94e-125
mismatched DNA binding	Hs	molecular function	396	3.94e-125
guanine/thymine mispair binding	Hs	molecular function	156	2.62e-39
single base insertion or deletion binding	Hs	molecular function	396	3.94e-125
mismatch repair complex	Hs	cellular component	156	2.62e-39
MutLalpha complex	Hs	cellular component	396	3.94e-125
MutSalpha complex binding	Hs	molecular function	396	3.94e-125
cytoplasmic ribonucleoprotein granule	Hs	cellular component	396	3.94e-125

GO (InterProScan)

5 results

GO Term	Analysis	Type	e-value
ATP binding	TIGRFAM	molecular function	2.0E-90
mismatch repair	TIGRFAM	biological process	2.0E-90
mismatched DNA binding	TIGRFAM	molecular function	2.0E-90
thiol oxidase activity	Gene3D	molecular function	4.0E-52
oxidation-reduction process	Gene3D	biological process	4.0E-52