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GENE CARD

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Gene Card

Best human hits

EGLN1; EGLN2; EGLN3

Unique Gene ID

Cirobu.g00011846

Gene Model ID

KH2012:KH.L171.18

Location

KhL171:18938..21407

External Database Gene Card

External database links

2 results

Collections

Gateway full ORF

2 results

cien123482

Plate: VES89_K13

cien164904

Plate: VES95_C21

Gene collection 1 (N. Satoh)

2 results

cieg014n02

Plate: R1CiGC17n17

cicl018l05

Plate: R1CiGC10b20

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
Oxoglu/Fe-dep_dioxygenase ProSiteProfiles Oxoglutarate/iron-dependent dioxygenase
Oxoglu/Fe-dep_dioxygenase Pfam Oxoglutarate/iron-dependent dioxygenase
Znf_MYND ProSiteProfiles Zinc finger, MYND-type
Znf_MYND Pfam Zinc finger, MYND-type
Pro_4_hyd_alph SMART Prolyl 4-hydroxylase, alpha subunit

GOSlim

38 results

GO Term Annotation Origin Type
response to hypoxia Orthology biological process
iron ion binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
apoptotic process Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
enzyme binding Orthology molecular function
regulation of cell proliferation Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
oxidation-reduction process Orthology biological process
cellular component organization Orthology biological process
cellular process Orthology biological process
cell Orthology cellular component
endopeptidase activity Orthology molecular function
positive regulation of hydrolase activity Orthology biological process
positive regulation of apoptotic process Orthology biological process
catalytic activity Orthology molecular function
cellular protein modification process Orthology biological process
small molecule binding Orthology molecular function
signal transduction Orthology biological process
response to lipid Orthology biological process
cellular response to organic substance Orthology biological process
anion binding Orthology molecular function
coenzyme binding Orthology molecular function
regulation of molecular function Orthology biological process
transcription factor activity, sequence-specific DNA binding Orthology molecular function
regulation of apoptotic process Orthology biological process
protein metabolic process Orthology biological process
angiogenesis Orthology biological process
heart development Orthology biological process
anatomical structure morphogenesis Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
response to oxidative stress Orthology biological process
regulation of cell death Orthology biological process

GO (Orthology)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
regulation of cell growth Hs biological process
response to hypoxia Hs biological process
iron ion binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cellular iron ion homeostasis Hs biological process
apoptotic process Hs biological process
activation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
ferrous iron binding Hs molecular function
oxidoreductase activity Hs molecular function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Hs molecular function
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Hs molecular function
protein hydroxylation Hs biological process
peptidyl-proline hydroxylation to 4-hydroxy-L-proline Hs biological process
oxygen sensor activity Hs molecular function
enzyme binding Hs molecular function
intracellular estrogen receptor signaling pathway Hs biological process
L-ascorbic acid binding Hs molecular function
peptidyl-proline dioxygenase activity Hs molecular function
peptidyl-proline 4-dioxygenase activity Hs molecular function
regulation of cell proliferation Hs biological process
negative regulation of sequence-specific DNA binding transcription factor activity Hs biological process
regulation of neuron apoptotic process Hs biological process
cell redox homeostasis Hs biological process
positive regulation of protein catabolic process Hs biological process
regulation of angiogenesis Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
dioxygenase activity Hs molecular function
cardiac muscle tissue morphogenesis Hs biological process
oxidation-reduction process Hs biological process
heart trabecula formation Hs biological process
response to nitric oxide Hs biological process
regulation of neuron death Hs biological process

GO (Blast)

17 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
iron ion binding Hs molecular function 204 1.10e-62
protein binding Hs molecular function 204 1.10e-62
nucleus Hs cellular component 204 1.10e-62
nucleoplasm Hs cellular component 190 3.09e-59
cytoplasm Hs cellular component 204 1.10e-62
cytosol Hs cellular component 204 1.10e-62
ferrous iron binding Hs molecular function 189 1.04e-56
oxidoreductase activity Hs molecular function 204 1.10e-62
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Hs molecular function 204 1.10e-62
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Hs molecular function 204 1.10e-62
oxygen sensor activity Hs molecular function 189 1.04e-56
enzyme binding Hs molecular function 204 1.10e-62
L-ascorbic acid binding Hs molecular function 204 1.10e-62
peptidyl-proline dioxygenase activity Hs molecular function 204 1.10e-62
peptidyl-proline 4-dioxygenase activity Hs molecular function 204 1.10e-62
metal ion binding Hs molecular function 204 1.10e-62
dioxygenase activity Hs molecular function 204 1.10e-62

GO (InterProScan)

5 results

GO Term Analysis Type e-value
iron ion binding SMART molecular function 1.8E-25
oxidoreductase activity Pfam molecular function 3.8E-21
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen SMART molecular function 1.8E-25
L-ascorbic acid binding SMART molecular function 1.8E-25
oxidation-reduction process SMART biological process 1.8E-25