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GENE CARD

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Gene Card

Best human hits

NOTCH1; NOTCH2; NOTCH3

Unique Gene ID

Cirobu.g00008332

Gene Model ID

KH2012:KH.C7.481

Location

KhC7:3039857..3061504

Collections

Gene collection 1 (N. Satoh)

1 result

cibd001f22

Plate: R1CiGC37i14

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term Analysis Definition
EGF-like_CS ProSitePatterns EGF-like, conserved site
EGF-like_dom ProSiteProfiles EGF-like domain
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain
EGF-type_Asp/Asn_hydroxyl_site ProSitePatterns EGF-type aspartate/asparagine hydroxylation site
EGF-like_CS Pfam EGF-like, conserved site
EGF-like_dom Pfam EGF-like domain
Ig-like_fold Gene3D Immunoglobulin-like fold
FN3_sf SUPERFAMILY Fibronectin type III superfamily
EGF_Ca-bd_CS ProSitePatterns EGF-like calcium-binding, conserved site
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
EGF-like_dom SMART EGF-like domain
FN3_dom SMART Fibronectin type III
FN3_dom CDD Fibronectin type III
GPCR_2_secretin-like Pfam GPCR, family 2, secretin-like
GPCR_2-like ProSiteProfiles GPCR, family 2-like
FN3_dom ProSiteProfiles Fibronectin type III

GOSlim

39 results

GO Term Annotation Origin Type
Golgi membrane Blast cellular component
chromatin binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Blast molecular function
transmembrane signaling receptor activity Blast molecular function
calcium ion binding Blast molecular function
protein binding Blast molecular function
extracellular region Blast cellular component
nucleus Blast cellular component
nucleoplasm Blast cellular component
cytoplasm Blast cellular component
endoplasmic reticulum Blast cellular component
endoplasmic reticulum membrane Blast cellular component
Golgi apparatus Blast cellular component
cytosol Blast cellular component
plasma membrane Blast cellular component
integral component of plasma membrane Blast cellular component
adherens junction Blast cellular component
cell surface Blast cellular component
membrane Blast cellular component
integral component of membrane Blast cellular component
apical plasma membrane Blast cellular component
enzyme binding Blast molecular function
cytoplasmic vesicle Blast cellular component
identical protein binding Blast molecular function
sequence-specific DNA binding Blast molecular function
metal ion binding Blast molecular function
protein heterodimerization activity Blast molecular function
cell periphery Blast cellular component
G-protein coupled receptor activity InterProScan molecular function
cell surface receptor signaling pathway InterProScan biological process
G-protein coupled receptor signaling pathway InterProScan biological process
transcription regulatory region DNA binding Blast molecular function
endomembrane system Blast cellular component
macromolecular complex Blast cellular component
enzyme regulator activity Blast molecular function
receptor binding Blast molecular function
cytoskeleton Blast cellular component
DNA binding Blast molecular function
cell adhesion molecule binding Blast molecular function

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

40 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 389 2.31e-111
core promoter binding Hs molecular function 354 7.14e-100
transcriptional activator activity, RNA polymerase II transcription factor binding Hs molecular function 354 7.14e-100
acrosomal vesicle Hs cellular component 354 7.14e-100
MAML1-RBP-Jkappa- ICN1 complex Hs cellular component 354 7.14e-100
chromatin binding Hs molecular function 354 7.14e-100
transcription factor activity, sequence-specific DNA binding Hs molecular function 354 7.14e-100
enzyme inhibitor activity Hs molecular function 354 7.14e-100
receptor activity Hs molecular function 389 2.31e-111
transmembrane signaling receptor activity Hs molecular function 354 7.14e-100
Notch binding Hs molecular function 354 7.14e-100
calcium ion binding Hs molecular function 389 2.31e-111
protein binding Hs molecular function 389 2.31e-111
extracellular region Hs cellular component 389 2.31e-111
nucleus Hs cellular component 389 2.31e-111
nucleoplasm Hs cellular component 389 2.31e-111
cytoplasm Hs cellular component 372 7.68e-106
endoplasmic reticulum Hs cellular component 354 7.14e-100
endoplasmic reticulum membrane Hs cellular component 389 2.31e-111
Golgi apparatus Hs cellular component 354 7.14e-100
cytosol Hs cellular component 389 2.31e-111
plasma membrane Hs cellular component 389 2.31e-111
integral component of plasma membrane Hs cellular component 372 7.68e-106
adherens junction Hs cellular component 354 7.14e-100
cell surface Hs cellular component 372 7.68e-106
actin cytoskeleton Hs cellular component 389 2.31e-111
membrane Hs cellular component 389 2.31e-111
integral component of membrane Hs cellular component 389 2.31e-111
apical plasma membrane Hs cellular component 354 7.14e-100
enzyme binding Hs molecular function 389 2.31e-111
cytoplasmic vesicle Hs cellular component 354 7.14e-100
chromatin DNA binding Hs molecular function 354 7.14e-100
transcription factor activity, ligand-activated RNA polymerase II transcription factor binding Hs molecular function 372 7.68e-106
identical protein binding Hs molecular function 389 2.31e-111
receptor complex Hs cellular component 389 2.31e-111
sequence-specific DNA binding Hs molecular function 354 7.14e-100
cadherin binding Hs molecular function 389 2.31e-111
metal ion binding Hs molecular function 354 7.14e-100
protein heterodimerization activity Hs molecular function 354 7.14e-100
cell periphery Hs cellular component 354 7.14e-100

GO (InterProScan)

7 results

GO Term Analysis Type e-value
transmembrane signaling receptor activity ProSiteProfiles molecular function 24.003
calcium ion binding SMART molecular function 1.2E-10
protein binding SUPERFAMILY molecular function 2.51E-13
integral component of membrane Pfam cellular component 1.2E-27
G-protein coupled receptor activity Pfam molecular function 1.2E-27
cell surface receptor signaling pathway ProSiteProfiles biological process 24.003
G-protein coupled receptor signaling pathway Pfam biological process 1.2E-27