Gene Card
Best human hits
NVL; SPATA5; VCP
Unique Gene ID
Cirobu.g00007149
Gene Model ID
KH2012:KH.C5.277
Location
KhC5:2578525..2587019
Transcript Models and Sequences
KH2012:KH.C5.277.v1.A.ND1-1
KH2012:KH.C5.277.v1.A.SL2-1
KH2012:KH.C5.277.v1.A.SL4-1
KH2012:KH.C5.277.v2.A.SL3-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000007091 |
cien73708
Plate: VES81_L21
cima838305
Plate: VES63_E08
ciad002b13
Plate: R1CiGC01i03
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
CDC4_N-term_subdom | Pfam | CDC48, N-terminal subdomain |
CDC48_domain_2-like_sf | SUPERFAMILY | CDC48 domain 2-like superfamily |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
Cdc48_dom2 | Pfam | CDC48, domain 2 |
ATPase_AAA_CS | ProSitePatterns | ATPase, AAA-type, conserved site |
ATPase_AAA_core | Pfam | ATPase, AAA-type, core |
Vps4_C | Pfam | Vps4 oligomerisation, C-terminal |
Asp_de-COase-like_dom_sf | SUPERFAMILY | Aspartate decarboxylase-like domain superfamily |
Cdc48_dom2 | SMART | CDC48, domain 2 |
AAA_ATPase_CDC48 | TIGRFAM | AAA ATPase, CDC48 family |
CDC4_N-term_subdom | SMART | CDC48, N-terminal subdomain |
AAA+_ATPase | SMART | AAA+ ATPase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
receptor binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
endoplasmic reticulum | Orthology | cellular component |
endoplasmic reticulum membrane | Orthology | cellular component |
cytosol | Orthology | cellular component |
DNA repair | Orthology | biological process |
protein folding | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
membrane | Blast | cellular component |
protein ubiquitination | Orthology | biological process |
hydrolase activity | Orthology | molecular function |
ubiquitin protein ligase binding | Orthology | molecular function |
macromolecular complex | Orthology | cellular component |
identical protein binding | Orthology | molecular function |
regulation of apoptotic process | Orthology | biological process |
myelin sheath | Orthology | cellular component |
intracellular membrane-bounded organelle | Orthology | cellular component |
ubiquitin-like protein ligase binding | Orthology | molecular function |
establishment of protein localization | Orthology | biological process |
perinuclear region of cytoplasm | Orthology | cellular component |
protein homooligomerization | Orthology | biological process |
transmembrane transport | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
intracellular part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
cellular protein modification process | Orthology | biological process |
proteolysis | Orthology | biological process |
metabolic process | Orthology | biological process |
intracellular transport | Orthology | biological process |
endopeptidase activity | Orthology | molecular function |
positive regulation of hydrolase activity | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
binding | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
nucleoside-triphosphatase activity | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
cellular response to stress | Orthology | biological process |
response to organic substance | Orthology | biological process |
signal transduction | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
intracellular protein transport | Orthology | biological process |
protein oligomerization | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
cytoplasmic vesicle | Orthology | cellular component |
endomembrane system | Orthology | cellular component |
intracellular organelle lumen | Orthology | cellular component |
lysosome | Orthology | cellular component |
vacuolar part | Orthology | cellular component |
enzyme activator activity | Orthology | molecular function |
anion binding | Orthology | molecular function |
adenyl ribonucleotide binding | Orthology | molecular function |
protein metabolic process | Orthology | biological process |
phosphorylation | Orthology | biological process |
monovalent inorganic cation transport | Orthology | biological process |
macromolecular complex binding | Orthology | molecular function |
cytoplasmic part | Orthology | cellular component |
phosphate-containing compound metabolic process | Orthology | biological process |
nuclear part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 1331 | 0.0 |
proteasome complex | Hs | cellular component | 1331 | 0.0 |
RNA binding | Hs | molecular function | 1331 | 0.0 |
receptor binding | Hs | molecular function | 1331 | 0.0 |
protein binding | Hs | molecular function | 1331 | 0.0 |
ATP binding | Hs | molecular function | 1331 | 0.0 |
extracellular region | Hs | cellular component | 1331 | 0.0 |
nucleus | Hs | cellular component | 1331 | 0.0 |
nucleoplasm | Hs | cellular component | 1331 | 0.0 |
telomerase holoenzyme complex | Hs | cellular component | 471 | 7.54e-154 |
nucleolus | Hs | cellular component | 471 | 7.54e-154 |
cytoplasm | Hs | cellular component | 1331 | 0.0 |
mitochondrion | Hs | cellular component | 553 | 0.0 |
endoplasmic reticulum | Hs | cellular component | 1331 | 0.0 |
endoplasmic reticulum membrane | Hs | cellular component | 1331 | 0.0 |
lipid droplet | Hs | cellular component | 1331 | 0.0 |
cytosol | Hs | cellular component | 1331 | 0.0 |
lipid binding | Hs | molecular function | 1331 | 0.0 |
membrane | Hs | cellular component | 471 | 7.54e-154 |
hydrolase activity | Hs | molecular function | 1331 | 0.0 |
ATPase activity | Hs | molecular function | 1331 | 0.0 |
protein phosphatase binding | Hs | molecular function | 1331 | 0.0 |
protein domain specific binding | Hs | molecular function | 1331 | 0.0 |
polyubiquitin modification-dependent protein binding | Hs | molecular function | 1331 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 1331 | 0.0 |
macromolecular complex | Hs | cellular component | 1331 | 0.0 |
VCP-NPL4-UFD1 AAA ATPase complex | Hs | cellular component | 1331 | 0.0 |
secretory granule lumen | Hs | cellular component | 1331 | 0.0 |
azurophil granule lumen | Hs | cellular component | 1331 | 0.0 |
deubiquitinase activator activity | Hs | molecular function | 1331 | 0.0 |
site of double-strand break | Hs | cellular component | 1331 | 0.0 |
K48-linked polyubiquitin modification-dependent protein binding | Hs | molecular function | 1331 | 0.0 |
Derlin-1 retrotranslocation complex | Hs | cellular component | 1331 | 0.0 |
MHC class I protein binding | Hs | molecular function | 1331 | 0.0 |
identical protein binding | Hs | molecular function | 1331 | 0.0 |
myelin sheath | Hs | cellular component | 1331 | 0.0 |
intracellular membrane-bounded organelle | Hs | cellular component | 1331 | 0.0 |
ADP binding | Hs | molecular function | 1331 | 0.0 |
ubiquitin-like protein ligase binding | Hs | molecular function | 1331 | 0.0 |
perinuclear region of cytoplasm | Hs | cellular component | 1331 | 0.0 |
extracellular exosome | Hs | cellular component | 1331 | 0.0 |
BAT3 complex binding | Hs | molecular function | 1331 | 0.0 |
ficolin-1-rich granule lumen | Hs | cellular component | 1331 | 0.0 |
ATPase complex | Hs | cellular component | 1331 | 0.0 |
preribosome binding | Hs | molecular function | 471 | 7.54e-154 |
ubiquitin-specific protease binding | Hs | molecular function | 1331 | 0.0 |
VCP-NSFL1C complex | Hs | cellular component | 1331 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ATP binding | Pfam | molecular function | 2.3E-46 |
hydrolase activity | TIGRFAM | molecular function | 5.9E-254 |