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GENE CARD

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Gene Card

Best human hits

NVL; SPATA5; VCP

Unique Gene ID

Cirobu.g00007149

Gene Model ID

KH2012:KH.C5.277

Location

KhC5:2578525..2587019

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000007091
Collections

Gateway full ORF

2 results

cien73708

Plate: VES81_L21

cima838305

Plate: VES63_E08

Gene collection 1 (N. Satoh)

1 result

ciad002b13

Plate: R1CiGC01i03

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
CDC4_N-term_subdom Pfam CDC48, N-terminal subdomain
CDC48_domain_2-like_sf SUPERFAMILY CDC48 domain 2-like superfamily
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
Cdc48_dom2 Pfam CDC48, domain 2
ATPase_AAA_CS ProSitePatterns ATPase, AAA-type, conserved site
ATPase_AAA_core Pfam ATPase, AAA-type, core
Vps4_C Pfam Vps4 oligomerisation, C-terminal
Asp_de-COase-like_dom_sf SUPERFAMILY Aspartate decarboxylase-like domain superfamily
Cdc48_dom2 SMART CDC48, domain 2
AAA_ATPase_CDC48 TIGRFAM AAA ATPase, CDC48 family
CDC4_N-term_subdom SMART CDC48, N-terminal subdomain
AAA+_ATPase SMART AAA+ ATPase domain

GOSlim

68 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
RNA binding Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Orthology cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Blast cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
endoplasmic reticulum Orthology cellular component
endoplasmic reticulum membrane Orthology cellular component
cytosol Orthology cellular component
DNA repair Orthology biological process
protein folding Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
membrane Blast cellular component
protein ubiquitination Orthology biological process
hydrolase activity Orthology molecular function
ubiquitin protein ligase binding Orthology molecular function
macromolecular complex Orthology cellular component
identical protein binding Orthology molecular function
regulation of apoptotic process Orthology biological process
myelin sheath Orthology cellular component
intracellular membrane-bounded organelle Orthology cellular component
ubiquitin-like protein ligase binding Orthology molecular function
establishment of protein localization Orthology biological process
perinuclear region of cytoplasm Orthology cellular component
protein homooligomerization Orthology biological process
transmembrane transport Orthology biological process
extracellular exosome Orthology cellular component
positive regulation of canonical Wnt signaling pathway Orthology biological process
intracellular part Orthology cellular component
intracellular non-membrane-bounded organelle Orthology cellular component
cellular protein modification process Orthology biological process
proteolysis Orthology biological process
metabolic process Orthology biological process
intracellular transport Orthology biological process
endopeptidase activity Orthology molecular function
positive regulation of hydrolase activity Orthology biological process
positive regulation of apoptotic process Orthology biological process
binding Orthology molecular function
peptidase activity, acting on L-amino acid peptides Orthology molecular function
nucleoside-triphosphatase activity Orthology molecular function
enzyme binding Orthology molecular function
cellular response to stress Orthology biological process
response to organic substance Orthology biological process
signal transduction Orthology biological process
cellular response to organic substance Orthology biological process
intracellular protein transport Orthology biological process
protein oligomerization Orthology biological process
intracellular organelle part Orthology cellular component
cytoplasmic vesicle Orthology cellular component
endomembrane system Orthology cellular component
intracellular organelle lumen Orthology cellular component
lysosome Orthology cellular component
vacuolar part Orthology cellular component
enzyme activator activity Orthology molecular function
anion binding Orthology molecular function
adenyl ribonucleotide binding Orthology molecular function
protein metabolic process Orthology biological process
phosphorylation Orthology biological process
monovalent inorganic cation transport Orthology biological process
macromolecular complex binding Orthology molecular function
cytoplasmic part Orthology cellular component
phosphate-containing compound metabolic process Orthology biological process
nuclear part Blast cellular component

GO (Orthology)

81 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
proteasome complex Hs cellular component
RNA binding Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular region Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
endoplasmic reticulum Hs cellular component
endoplasmic reticulum membrane Hs cellular component
lipid droplet Hs cellular component
cytosol Hs cellular component
DNA repair Hs biological process
double-strand break repair Hs biological process
protein folding Hs biological process
protein methylation Hs biological process
ubiquitin-dependent protein catabolic process Hs biological process
NADH metabolic process Hs biological process
ER to Golgi vesicle-mediated transport Hs biological process
autophagy Hs biological process
activation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
cellular response to DNA damage stimulus Hs biological process
lipid binding Hs molecular function
proteasomal protein catabolic process Hs biological process
positive regulation of mitochondrial membrane potential Hs biological process
macroautophagy Hs biological process
protein ubiquitination Hs biological process
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
protein N-linked glycosylation via asparagine Hs biological process
viral genome replication Hs biological process
protein phosphatase binding Hs molecular function
protein domain specific binding Hs molecular function
translesion synthesis Hs biological process
ubiquitin-dependent ERAD pathway Hs biological process
endoplasmic reticulum unfolded protein response Hs biological process
retrograde protein transport, ER to cytosol Hs biological process
positive regulation of protein complex assembly Hs biological process
polyubiquitin modification-dependent protein binding Hs molecular function
ubiquitin protein ligase binding Hs molecular function
positive regulation of proteasomal ubiquitin-dependent protein catabolic process Hs biological process
endosome to lysosome transport via multivesicular body sorting pathway Hs biological process
macromolecular complex Hs cellular component
VCP-NPL4-UFD1 AAA ATPase complex Hs cellular component
protein hexamerization Hs biological process
secretory granule lumen Hs cellular component
azurophil granule lumen Hs cellular component
deubiquitinase activator activity Hs molecular function
site of double-strand break Hs cellular component
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function
ERAD pathway Hs biological process
Derlin-1 retrotranslocation complex Hs cellular component
MHC class I protein binding Hs molecular function
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
myelin sheath Hs cellular component
intracellular membrane-bounded organelle Hs cellular component
ADP binding Hs molecular function
ubiquitin-like protein ligase binding Hs molecular function
establishment of protein localization Hs biological process
positive regulation of protein catabolic process Hs biological process
ATP metabolic process Hs biological process
perinuclear region of cytoplasm Hs cellular component
protein homooligomerization Hs biological process
transmembrane transport Hs biological process
extracellular exosome Hs cellular component
ER-associated misfolded protein catabolic process Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
autophagosome maturation Hs biological process
positive regulation of oxidative phosphorylation Hs biological process
BAT3 complex binding Hs molecular function
ficolin-1-rich granule lumen Hs cellular component
ATPase complex Hs cellular component
ubiquitin-specific protease binding Hs molecular function
VCP-NSFL1C complex Hs cellular component
positive regulation of ubiquitin-specific protease activity Hs biological process
positive regulation of ATP biosynthetic process Hs biological process

GO (Blast)

47 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 1331 0.0
proteasome complex Hs cellular component 1331 0.0
RNA binding Hs molecular function 1331 0.0
receptor binding Hs molecular function 1331 0.0
protein binding Hs molecular function 1331 0.0
ATP binding Hs molecular function 1331 0.0
extracellular region Hs cellular component 1331 0.0
nucleus Hs cellular component 1331 0.0
nucleoplasm Hs cellular component 1331 0.0
telomerase holoenzyme complex Hs cellular component 471 7.54e-154
nucleolus Hs cellular component 471 7.54e-154
cytoplasm Hs cellular component 1331 0.0
mitochondrion Hs cellular component 553 0.0
endoplasmic reticulum Hs cellular component 1331 0.0
endoplasmic reticulum membrane Hs cellular component 1331 0.0
lipid droplet Hs cellular component 1331 0.0
cytosol Hs cellular component 1331 0.0
lipid binding Hs molecular function 1331 0.0
membrane Hs cellular component 471 7.54e-154
hydrolase activity Hs molecular function 1331 0.0
ATPase activity Hs molecular function 1331 0.0
protein phosphatase binding Hs molecular function 1331 0.0
protein domain specific binding Hs molecular function 1331 0.0
polyubiquitin modification-dependent protein binding Hs molecular function 1331 0.0
ubiquitin protein ligase binding Hs molecular function 1331 0.0
macromolecular complex Hs cellular component 1331 0.0
VCP-NPL4-UFD1 AAA ATPase complex Hs cellular component 1331 0.0
secretory granule lumen Hs cellular component 1331 0.0
azurophil granule lumen Hs cellular component 1331 0.0
deubiquitinase activator activity Hs molecular function 1331 0.0
site of double-strand break Hs cellular component 1331 0.0
K48-linked polyubiquitin modification-dependent protein binding Hs molecular function 1331 0.0
Derlin-1 retrotranslocation complex Hs cellular component 1331 0.0
MHC class I protein binding Hs molecular function 1331 0.0
identical protein binding Hs molecular function 1331 0.0
myelin sheath Hs cellular component 1331 0.0
intracellular membrane-bounded organelle Hs cellular component 1331 0.0
ADP binding Hs molecular function 1331 0.0
ubiquitin-like protein ligase binding Hs molecular function 1331 0.0
perinuclear region of cytoplasm Hs cellular component 1331 0.0
extracellular exosome Hs cellular component 1331 0.0
BAT3 complex binding Hs molecular function 1331 0.0
ficolin-1-rich granule lumen Hs cellular component 1331 0.0
ATPase complex Hs cellular component 1331 0.0
preribosome binding Hs molecular function 471 7.54e-154
ubiquitin-specific protease binding Hs molecular function 1331 0.0
VCP-NSFL1C complex Hs cellular component 1331 0.0

GO (InterProScan)

2 results

GO Term Analysis Type e-value
ATP binding Pfam molecular function 2.3E-46
hydrolase activity TIGRFAM molecular function 5.9E-254