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- Gene 'KH2012:KH.S390.2' >
Gene Card
Best human hits
AL359736.1; ARHGEF9; SPATA13
Unique Gene ID
Cirobu.g00006526
Gene Model ID
KH2012:KH.C4.435
Location
KhC4:853259..868885
Transcript Models and Sequences
KH2012:KH.C4.435.v1.A.SL2-1
KH2012:KH.C4.435.v2.A.nonSL11-1
KH2012:KH.C4.435.v2.A.nonSL5-1
KH2012:KH.C4.435.v2.A.nonSL8-1
KH2012:KH.C4.435.v2.A.SL1-1
KH2012:KH.C4.435.v2.A.SL3-1
KH2012:KH.C4.435.v3.A.nonSL6-1
KH2012:KH.C4.435.v3.A.SL10-1
KH2012:KH.C4.435.v3.A.SL12-1
KH2012:KH.C4.435.v3.A.SL4-1
KH2012:KH.C4.435.v3.A.SL7-1
KH2012:KH.C4.435.v3.A.SL9-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000024938 |
NCBI Reference Sequence | XM_002121597.3 |
cien94511
Plate: VES85_D05
cien172441
Plate: VES96_I23
cieg007g02
Plate: R1CiGC16f23
ciad013e05
Plate: R1CiGC02i06
n/a
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IPR Term | Analysis | Definition |
---|---|---|
PH_domain | ProSiteProfiles | Pleckstrin homology domain |
DH-domain | CDD | Dbl homology (DH) domain |
DH-domain | ProSiteProfiles | Dbl homology (DH) domain |
PH_domain | SMART | Pleckstrin homology domain |
DBL_dom_sf | Gene3D | Dbl homology (DH) domain superfamily |
SH3-like_dom_sf | SUPERFAMILY | SH3-like domain superfamily |
PH-like_dom_sf | Gene3D | PH-like domain superfamily |
SH3_domain | Pfam | SH3 domain |
SH3_domain | SMART | SH3 domain |
GDS_CDC24_CS | ProSitePatterns | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
DBL_dom_sf | SUPERFAMILY | Dbl homology (DH) domain superfamily |
DH-domain | Pfam | Dbl homology (DH) domain |
DH-domain | SMART | Dbl homology (DH) domain |
SH3_domain | ProSiteProfiles | SH3 domain |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
G-protein coupled receptor signaling pathway | Orthology | biological process |
membrane | Orthology | cellular component |
cell migration | Orthology | biological process |
lamellipodium | Orthology | cellular component |
cell projection | Orthology | cellular component |
positive regulation of apoptotic process | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
intracellular | Orthology | cellular component |
enzyme binding | Orthology | molecular function |
molecular function regulator | Orthology | molecular function |
cell projection assembly | Orthology | biological process |
plasma membrane region | Orthology | cellular component |
cytoskeletal part | Orthology | cellular component |
cell projection membrane | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
small GTPase mediated signal transduction | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
guanyl-nucleotide exchange factor activity | Hs | molecular function |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
G-protein coupled receptor signaling pathway | Hs | biological process |
membrane | Hs | cellular component |
cell migration | Hs | biological process |
lamellipodium | Hs | cellular component |
lamellipodium assembly | Hs | biological process |
filopodium | Hs | cellular component |
regulation of cell migration | Hs | biological process |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function |
ruffle membrane | Hs | cellular component |
regulation of Rho protein signal transduction | Hs | biological process |
cell projection | Hs | cellular component |
positive regulation of apoptotic process | Hs | biological process |
filopodium assembly | Hs | biological process |
regulation of small GTPase mediated signal transduction | Hs | biological process |
regulation of molecular function | Hs | biological process |
intracellular signal transduction | Hs | biological process |
intracellular | Hs | cellular component |
protein domain specific binding | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
guanyl-nucleotide exchange factor activity | Hs | molecular function | 435 | 2.26e-135 |
Rho guanyl-nucleotide exchange factor activity | Hs | molecular function | 435 | 2.26e-135 |
protein binding | Hs | molecular function | 435 | 2.26e-135 |
nucleoplasm | Hs | cellular component | 395 | 3.86e-114 |
cytoplasm | Hs | cellular component | 435 | 2.26e-135 |
cytosol | Hs | cellular component | 435 | 2.26e-135 |
plasma membrane | Hs | cellular component | 395 | 3.86e-114 |
membrane | Hs | cellular component | 395 | 3.86e-114 |
lamellipodium | Hs | cellular component | 395 | 3.86e-114 |
filopodium | Hs | cellular component | 395 | 3.86e-114 |
Rac guanyl-nucleotide exchange factor activity | Hs | molecular function | 395 | 3.86e-114 |
ruffle membrane | Hs | cellular component | 395 | 3.86e-114 |
cell projection | Hs | cellular component | 395 | 3.86e-114 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
guanyl-nucleotide exchange factor activity | ProSitePatterns | molecular function | |
Rho guanyl-nucleotide exchange factor activity | SMART | molecular function | 2.0E-61 |
protein binding | SUPERFAMILY | molecular function | 1.22E-20 |
regulation of Rho protein signal transduction | SMART | biological process | 2.0E-61 |
intracellular signal transduction | ProSitePatterns | biological process |