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Gene Card

Best human hits

TRAF2; TRAF4; TRAF6

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006481

Gene Model ID

KH2012:KH.C4.394

Location

KhC4:1603286..1614244

Transcript Models and Sequences

  KH2012:KH.C4.394.v1.A.SL1-1
KH2012:KH.C4.394.v1.A.SL2-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000004316
NCBI Reference Sequence NM_001129866.1
Collections

Gateway full ORF

2 results

cien96112

Plate: VES85_I11

cima871886

Plate: VES66_N22

Gene collection 1 (N. Satoh)

2 results

citb1d13

Plate: R1CiGC28d17

cilv018j19

Plate: R1CiGC26j09

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
Znf_TRAF Pfam Zinc finger, TRAF-type
Znf_TRAF ProSiteProfiles Zinc finger, TRAF-type
TRAF-like SUPERFAMILY TRAF-like
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
MATH/TRAF_dom SMART MATH/TRAF domain
TNF_rcpt--assoc_TRAF PIRSF TNF receptor-associated factor TRAF
Znf_RING SMART Zinc finger, RING-type
MATH/TRAF_dom ProSiteProfiles MATH/TRAF domain
Znf_RING_CS ProSitePatterns Zinc finger, RING-type, conserved site
TRAF-like Gene3D TRAF-like
TRAF4_MATH CDD TNF receptor-associated factor 4, MATH domain
Znf_RING ProSiteProfiles Zinc finger, RING-type

GOSlim

51 results

GO Term Annotation Origin Type
DNA binding Orthology molecular function
ubiquitin-protein transferase activity Blast molecular function
signal transducer activity Blast molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
nucleoplasm Blast cellular component
cytoplasm Orthology cellular component
cytosol Blast cellular component
cytoskeleton Orthology cellular component
plasma membrane Orthology cellular component
apoptotic process Orthology biological process
signal transduction Orthology biological process
multicellular organism development Orthology biological process
zinc ion binding Orthology molecular function
membrane Orthology cellular component
transferase activity Blast molecular function
enzyme binding Orthology molecular function
protein kinase binding Orthology molecular function
cell junction Orthology cellular component
ubiquitin protein ligase binding Orthology molecular function
macromolecular complex Blast cellular component
identical protein binding Orthology molecular function
regulation of apoptotic process Orthology biological process
membrane raft Blast cellular component
metal ion binding Orthology molecular function
protein N-terminus binding Blast molecular function
perinuclear region of cytoplasm Orthology cellular component
positive regulation of catalytic activity Orthology biological process
enzyme regulator activity Orthology molecular function
protein kinase activity Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
intracellular signal transduction Orthology biological process
positive regulation of signal transduction Orthology biological process
cellular response to stress Orthology biological process
protein phosphorylation Orthology biological process
intracellular part Blast cellular component
intracellular non-membrane-bounded organelle Blast cellular component
cell periphery Blast cellular component
cytoplasmic part Blast cellular component
binding Blast molecular function
plasma membrane part Blast cellular component
intracellular organelle part Blast cellular component
whole membrane Blast cellular component
endosome Blast cellular component
bounding membrane of organelle Blast cellular component
vesicle Blast cellular component
organelle membrane Blast cellular component
integral component of plasma membrane Blast cellular component
endoplasmic reticulum membrane Blast cellular component

GO (Orthology)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
DNA binding Hs molecular function
tumor necrosis factor receptor binding Hs molecular function
protein binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
cytoskeleton Hs cellular component
plasma membrane Hs cellular component
bicellular tight junction Hs cellular component
apoptotic process Hs biological process
signal transduction Hs biological process
activation of NF-kappaB-inducing kinase activity Hs biological process
multicellular organism development Hs biological process
zinc ion binding Hs molecular function
membrane Hs cellular component
protein kinase binding Hs molecular function
cell junction Hs cellular component
ubiquitin protein ligase binding Hs molecular function
thioesterase binding Hs molecular function
identical protein binding Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of protein kinase activity Hs biological process
positive regulation of JNK cascade Hs biological process
metal ion binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
WW domain binding Hs molecular function

GO (Blast)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
ubiquitin ligase complex Hs cellular component 180 3.53e-51
DNA binding Hs molecular function 549 0.0
ubiquitin-protein transferase activity Hs molecular function 180 3.53e-51
signal transducer activity Hs molecular function 180 3.53e-51
receptor binding Hs molecular function 180 3.53e-51
tumor necrosis factor receptor binding Hs molecular function 549 0.0
CD40 receptor binding Hs molecular function 180 3.53e-51
protein binding Hs molecular function 549 0.0
intracellular Hs cellular component 549 0.0
nucleus Hs cellular component 549 0.0
nucleoplasm Hs cellular component 180 3.53e-51
cytoplasm Hs cellular component 549 0.0
lipid droplet Hs cellular component 180 5.37e-51
cytosol Hs cellular component 180 3.53e-51
cytoskeleton Hs cellular component 549 0.0
plasma membrane Hs cellular component 549 0.0
bicellular tight junction Hs cellular component 549 0.0
cell cortex Hs cellular component 180 3.53e-51
zinc ion binding Hs molecular function 549 0.0
lipid binding Hs molecular function 180 3.53e-51
cytoplasmic side of plasma membrane Hs cellular component 180 3.53e-51
endosome membrane Hs cellular component 180 5.37e-51
vesicle membrane Hs cellular component 180 3.53e-51
membrane Hs cellular component 549 0.0
transferase activity Hs molecular function 180 3.53e-51
enzyme binding Hs molecular function 180 3.53e-51
protein kinase binding Hs molecular function 549 0.0
protein phosphatase binding Hs molecular function 180 3.53e-51
cell junction Hs cellular component 549 0.0
mitogen-activated protein kinase kinase kinase binding Hs molecular function 180 3.53e-51
ubiquitin conjugating enzyme binding Hs molecular function 180 5.37e-51
ubiquitin protein ligase binding Hs molecular function 549 0.0
thioesterase binding Hs molecular function 549 0.0
macromolecular complex Hs cellular component 180 5.37e-51
CD40 receptor complex Hs cellular component 180 3.53e-51
identical protein binding Hs molecular function 549 0.0
histone deacetylase binding Hs molecular function 180 5.37e-51
protein kinase B binding Hs molecular function 180 5.37e-51
membrane raft Hs cellular component 180 3.53e-51
sphingolipid binding Hs molecular function 180 3.53e-51
metal ion binding Hs molecular function 549 0.0
protein N-terminus binding Hs molecular function 180 5.37e-51
perinuclear region of cytoplasm Hs cellular component 549 0.0
WW domain binding Hs molecular function 549 0.0
ubiquitin protein ligase activity Hs molecular function 180 5.37e-51
TRAF2-GSTP1 complex Hs cellular component 180 3.53e-51
AIP1-IRE1 complex Hs cellular component 180 3.53e-51
IRE1-TRAF2-ASK1 complex Hs cellular component 180 3.53e-51

GO (InterProScan)

6 results

GO Term Analysis Type e-value
protein binding Gene3D molecular function 5.2E-63
signal transduction PIRSF biological process 6.3E-68
activation of NF-kappaB-inducing kinase activity CDD biological process 8.24103E-110
zinc ion binding PIRSF molecular function 6.3E-68
regulation of apoptotic process PIRSF biological process 6.3E-68
positive regulation of JNK cascade CDD biological process 8.24103E-110

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