Gene Card
Best human hits
LRP1; LRP2; LRP4
Unique Gene ID
Cirobu.g00006418
Gene Model ID
KH2012:KH.C4.335
Location
KhC4:418784..439480
cicl060n23
Plate: R1CiGC15c18
citb038a22
Plate: R1CiGC32b23
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
LDrepeatLR_classA_rpt | CDD | Low-density lipoprotein (LDL) receptor class A repeat |
LDrepeatLR_classA_rpt | ProSiteProfiles | Low-density lipoprotein (LDL) receptor class A repeat |
LDLR_classB_rpt | ProSiteProfiles | LDLR class B repeat |
6-blade_b-propeller_TolB-like | Gene3D | Six-bladed beta-propeller, TolB-like |
LDLR_class-A_CS | ProSitePatterns | Low-density lipoprotein (LDL) receptor class A, conserved site |
EGF-like_CS | ProSitePatterns | EGF-like, conserved site |
EGF-like_Ca-bd_dom | SMART | EGF-like calcium-binding domain |
LDL_receptor-like_sf | SUPERFAMILY | LDL receptor-like superfamily |
LRP4 | PANTHER | Low-density lipoprotein receptor-related protein 4 |
LDLR_classB_rpt | Pfam | LDLR class B repeat |
LDrepeatLR_classA_rpt | PRINTS | Low-density lipoprotein (LDL) receptor class A repeat |
EGF-like_dom | SMART | EGF-like domain |
LDrepeatLR_classA_rpt | SMART | Low-density lipoprotein (LDL) receptor class A repeat |
EGF_Ca-bd_CS | ProSitePatterns | EGF-like calcium-binding, conserved site |
LDLR_classB_rpt | SMART | LDLR class B repeat |
Growth_fac_rcpt_cys_sf | SUPERFAMILY | Growth factor receptor cysteine-rich domain superfamily |
LDrepeatLR_classA_rpt | Pfam | Low-density lipoprotein (LDL) receptor class A repeat |
EGF-like_Ca-bd_dom | Pfam | EGF-like calcium-binding domain |
EGF-type_Asp/Asn_hydroxyl_site | ProSitePatterns | EGF-type aspartate/asparagine hydroxylation site |
GO Term | Annotation Origin | Type |
---|---|---|
RNA binding | Blast | molecular function |
calcium ion binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
cytoplasm | Blast | cellular component |
lysosome | Blast | cellular component |
lysosomal membrane | Blast | cellular component |
endosome | Blast | cellular component |
early endosome | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Blast | cellular component |
brush border | Blast | cellular component |
focal adhesion | Blast | cellular component |
multicellular organism development | Orthology | biological process |
nervous system development | Orthology | biological process |
protein localization | Orthology | biological process |
cell surface | Orthology | cellular component |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
basolateral plasma membrane | Blast | cellular component |
apical plasma membrane | Blast | cellular component |
cell differentiation | Orthology | biological process |
negative regulation of Wnt signaling pathway | Orthology | biological process |
axon | Blast | cellular component |
brush border membrane | Blast | cellular component |
protein homodimerization activity | Orthology | molecular function |
cell projection | Blast | cellular component |
neuronal cell body | Orthology | cellular component |
macromolecular complex binding | Blast | molecular function |
apical part of cell | Blast | cellular component |
metal ion binding | Blast | molecular function |
animal organ development | Orthology | biological process |
anatomical structure development | Orthology | biological process |
regulation of canonical Wnt signaling pathway | Orthology | biological process |
membrane organization | Orthology | biological process |
extracellular exosome | Blast | cellular component |
negative regulation of canonical Wnt signaling pathway | Orthology | biological process |
synaptic membrane | Orthology | cellular component |
regulation of cellular metabolic process | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
organelle organization | Orthology | biological process |
organelle | Orthology | cellular component |
postsynapse | Orthology | cellular component |
neuron part | Orthology | cellular component |
cell surface receptor signaling pathway | Orthology | biological process |
cell-cell signaling | Orthology | biological process |
plasma membrane region | Orthology | cellular component |
membrane raft | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
anatomical structure morphogenesis | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
receptor binding | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
synapse | Orthology | cellular component |
transmembrane signaling receptor activity | Orthology | molecular function |
protein localization to membrane | Orthology | biological process |
cell morphogenesis involved in neuron differentiation | Orthology | biological process |
neuron projection morphogenesis | Orthology | biological process |
axonogenesis | Orthology | biological process |
cellular component organization | Orthology | biological process |
protein oligomerization | Orthology | biological process |
enzyme binding | Blast | molecular function |
membrane part | Blast | cellular component |
endomembrane system | Blast | cellular component |
binding | Blast | molecular function |
plasma membrane part | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
transcription factor binding | Blast | molecular function |
protein transport | Blast | biological process |
anion binding | Blast | molecular function |
carbohydrate derivative binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protease binding | Hs | molecular function | 864 | 0.0 |
RNA binding | Hs | molecular function | 864 | 0.0 |
receptor activity | Hs | molecular function | 864 | 0.0 |
low-density lipoprotein receptor activity | Hs | molecular function | 864 | 0.0 |
scavenger receptor activity | Hs | molecular function | 864 | 0.0 |
calcium ion binding | Hs | molecular function | 1650 | 0.0 |
protein binding | Hs | molecular function | 1650 | 0.0 |
nucleus | Hs | cellular component | 864 | 0.0 |
cytoplasm | Hs | cellular component | 864 | 0.0 |
lysosome | Hs | cellular component | 801 | 0.0 |
lysosomal membrane | Hs | cellular component | 864 | 0.0 |
endosome | Hs | cellular component | 864 | 0.0 |
early endosome | Hs | cellular component | 864 | 0.0 |
endoplasmic reticulum | Hs | cellular component | 801 | 0.0 |
Golgi apparatus | Hs | cellular component | 801 | 0.0 |
plasma membrane | Hs | cellular component | 1650 | 0.0 |
integral component of plasma membrane | Hs | cellular component | 864 | 0.0 |
brush border | Hs | cellular component | 801 | 0.0 |
clathrin-coated pit | Hs | cellular component | 864 | 0.0 |
focal adhesion | Hs | cellular component | 864 | 0.0 |
drug binding | Hs | molecular function | 801 | 0.0 |
external side of plasma membrane | Hs | cellular component | 801 | 0.0 |
cell surface | Hs | cellular component | 1650 | 0.0 |
postsynaptic density | Hs | cellular component | 1650 | 0.0 |
membrane | Hs | cellular component | 1650 | 0.0 |
integral component of membrane | Hs | cellular component | 1650 | 0.0 |
basolateral plasma membrane | Hs | cellular component | 864 | 0.0 |
apical plasma membrane | Hs | cellular component | 801 | 0.0 |
flotillin complex | Hs | cellular component | 1650 | 0.0 |
alpha-2 macroglobulin receptor activity | Hs | molecular function | 864 | 0.0 |
SH3 domain binding | Hs | molecular function | 801 | 0.0 |
Wnt-protein binding | Hs | molecular function | 1650 | 0.0 |
clathrin-coated vesicle | Hs | cellular component | 864 | 0.0 |
endocytic vesicle | Hs | cellular component | 801 | 0.0 |
apolipoprotein receptor activity | Hs | molecular function | 864 | 0.0 |
axon | Hs | cellular component | 801 | 0.0 |
dendrite | Hs | cellular component | 1650 | 0.0 |
clathrin-coated vesicle membrane | Hs | cellular component | 801 | 0.0 |
endocytic vesicle membrane | Hs | cellular component | 864 | 0.0 |
receptor tyrosine kinase binding | Hs | molecular function | 1650 | 0.0 |
brush border membrane | Hs | cellular component | 801 | 0.0 |
neuromuscular junction | Hs | cellular component | 1650 | 0.0 |
endosome lumen | Hs | cellular component | 801 | 0.0 |
clathrin heavy chain binding | Hs | molecular function | 864 | 0.0 |
apolipoprotein binding | Hs | molecular function | 1650 | 0.0 |
steroid hormone receptor binding | Hs | molecular function | 801 | 0.0 |
protein homodimerization activity | Hs | molecular function | 1650 | 0.0 |
Wnt-activated receptor activity | Hs | molecular function | 1650 | 0.0 |
lipoprotein transporter activity | Hs | molecular function | 864 | 0.0 |
cell projection | Hs | cellular component | 801 | 0.0 |
neuronal cell body | Hs | cellular component | 1650 | 0.0 |
receptor complex | Hs | cellular component | 1650 | 0.0 |
heparan sulfate proteoglycan binding | Hs | molecular function | 864 | 0.0 |
macromolecular complex binding | Hs | molecular function | 864 | 0.0 |
apical part of cell | Hs | cellular component | 801 | 0.0 |
metal ion binding | Hs | molecular function | 864 | 0.0 |
chaperone binding | Hs | molecular function | 801 | 0.0 |
extracellular exosome | Hs | cellular component | 801 | 0.0 |
lipoprotein particle receptor binding | Hs | molecular function | 864 | 0.0 |
synaptic membrane | Hs | cellular component | 1650 | 0.0 |
scaffold protein binding | Hs | molecular function | 1650 | 0.0 |
plasma membrane protein complex | Hs | cellular component | 864 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
calcium ion binding | SMART | molecular function | 9.9E-9 |
protein binding | PRINTS | molecular function | 3.2E-53 |
BMP signaling pathway | PANTHER | biological process | 0.0 |
animal organ development | PANTHER | biological process | 0.0 |
regulation of canonical Wnt signaling pathway | PANTHER | biological process | 0.0 |