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GENE CARD

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Gene Card

Best human hits

LRP1; LRP2; LRP4

Unique Gene ID

Cirobu.g00006418

Gene Model ID

KH2012:KH.C4.335

Location

KhC4:418784..439480

Collections

Gateway full ORF

2 results

cien54071

Plate: VES78_J17

cien63478

Plate: VES80_I06

Gene collection 1 (N. Satoh)

2 results

cicl060n23

Plate: R1CiGC15c18

citb038a22

Plate: R1CiGC32b23

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

19 results

IPR Term Analysis Definition
LDrepeatLR_classA_rpt CDD Low-density lipoprotein (LDL) receptor class A repeat
LDrepeatLR_classA_rpt ProSiteProfiles Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt ProSiteProfiles LDLR class B repeat
6-blade_b-propeller_TolB-like Gene3D Six-bladed beta-propeller, TolB-like
LDLR_class-A_CS ProSitePatterns Low-density lipoprotein (LDL) receptor class A, conserved site
EGF-like_CS ProSitePatterns EGF-like, conserved site
EGF-like_Ca-bd_dom SMART EGF-like calcium-binding domain
LDL_receptor-like_sf SUPERFAMILY LDL receptor-like superfamily
LRP4 PANTHER Low-density lipoprotein receptor-related protein 4
LDLR_classB_rpt Pfam LDLR class B repeat
LDrepeatLR_classA_rpt PRINTS Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_dom SMART EGF-like domain
LDrepeatLR_classA_rpt SMART Low-density lipoprotein (LDL) receptor class A repeat
EGF_Ca-bd_CS ProSitePatterns EGF-like calcium-binding, conserved site
LDLR_classB_rpt SMART LDLR class B repeat
Growth_fac_rcpt_cys_sf SUPERFAMILY Growth factor receptor cysteine-rich domain superfamily
LDrepeatLR_classA_rpt Pfam Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_Ca-bd_dom Pfam EGF-like calcium-binding domain
EGF-type_Asp/Asn_hydroxyl_site ProSitePatterns EGF-type aspartate/asparagine hydroxylation site

GOSlim

78 results

GO Term Annotation Origin Type
RNA binding Blast molecular function
calcium ion binding Orthology molecular function
protein binding Orthology molecular function
nucleus Blast cellular component
cytoplasm Blast cellular component
lysosome Blast cellular component
lysosomal membrane Blast cellular component
endosome Blast cellular component
early endosome Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
plasma membrane Orthology cellular component
integral component of plasma membrane Blast cellular component
brush border Blast cellular component
focal adhesion Blast cellular component
multicellular organism development Orthology biological process
nervous system development Orthology biological process
protein localization Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
integral component of membrane Orthology cellular component
basolateral plasma membrane Blast cellular component
apical plasma membrane Blast cellular component
cell differentiation Orthology biological process
negative regulation of Wnt signaling pathway Orthology biological process
axon Blast cellular component
brush border membrane Blast cellular component
protein homodimerization activity Orthology molecular function
cell projection Blast cellular component
neuronal cell body Orthology cellular component
macromolecular complex binding Blast molecular function
apical part of cell Blast cellular component
metal ion binding Blast molecular function
animal organ development Orthology biological process
anatomical structure development Orthology biological process
regulation of canonical Wnt signaling pathway Orthology biological process
membrane organization Orthology biological process
extracellular exosome Blast cellular component
negative regulation of canonical Wnt signaling pathway Orthology biological process
synaptic membrane Orthology cellular component
regulation of cellular metabolic process Orthology biological process
protein phosphorylation Orthology biological process
organelle organization Orthology biological process
organelle Orthology cellular component
postsynapse Orthology cellular component
neuron part Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
plasma membrane region Orthology cellular component
membrane raft Orthology cellular component
macromolecular complex Orthology cellular component
anatomical structure morphogenesis Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
receptor binding Orthology molecular function
protein kinase binding Orthology molecular function
synapse Orthology cellular component
transmembrane signaling receptor activity Orthology molecular function
protein localization to membrane Orthology biological process
cell morphogenesis involved in neuron differentiation Orthology biological process
neuron projection morphogenesis Orthology biological process
axonogenesis Orthology biological process
cellular component organization Orthology biological process
protein oligomerization Orthology biological process
enzyme binding Blast molecular function
membrane part Blast cellular component
endomembrane system Blast cellular component
binding Blast molecular function
plasma membrane part Blast cellular component
cytoplasmic vesicle Blast cellular component
intracellular organelle part Blast cellular component
whole membrane Blast cellular component
bounding membrane of organelle Blast cellular component
intracellular organelle lumen Blast cellular component
transcription factor binding Blast molecular function
protein transport Blast biological process
anion binding Blast molecular function
carbohydrate derivative binding Blast molecular function

GO (Orthology)

49 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
kidney development Hs biological process
regulation of protein phosphorylation Hs biological process
calcium ion binding Hs molecular function
protein binding Hs molecular function
plasma membrane Hs cellular component
endocytosis Hs biological process
multicellular organism development Hs biological process
protein localization Hs biological process
dorsal/ventral pattern formation Hs biological process
proximal/distal pattern formation Hs biological process
cell surface Hs cellular component
postsynaptic density Hs cellular component
membrane Hs cellular component
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
flotillin complex Hs cellular component
Wnt-protein binding Hs molecular function
cell differentiation Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
negative regulation of ossification Hs biological process
embryonic limb morphogenesis Hs biological process
dendrite Hs cellular component
BMP signaling pathway Hs biological process
receptor tyrosine kinase binding Hs molecular function
neuromuscular junction Hs cellular component
apolipoprotein binding Hs molecular function
protein homodimerization activity Hs molecular function
Wnt-activated receptor activity Hs molecular function
neuronal cell body Hs cellular component
receptor clustering Hs biological process
receptor complex Hs cellular component
Wnt signaling pathway involved in dorsal/ventral axis specification Hs biological process
animal organ development Hs biological process
dendrite morphogenesis Hs biological process
anatomical structure development Hs biological process
positive regulation of peptidyl-tyrosine phosphorylation Hs biological process
negative regulation of axonogenesis Hs biological process
synapse organization Hs biological process
synaptic growth at neuromuscular junction Hs biological process
protein heterotetramerization Hs biological process
limb development Hs biological process
regulation of canonical Wnt signaling pathway Hs biological process
skeletal muscle acetylcholine-gated channel clustering Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
synaptic membrane Hs cellular component
postsynaptic membrane assembly Hs biological process
presynaptic membrane assembly Hs biological process
scaffold protein binding Hs molecular function
positive regulation of skeletal muscle acetylcholine-gated channel clustering Hs biological process

GO (Blast)

62 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
protease binding Hs molecular function 864 0.0
RNA binding Hs molecular function 864 0.0
receptor activity Hs molecular function 864 0.0
low-density lipoprotein receptor activity Hs molecular function 864 0.0
scavenger receptor activity Hs molecular function 864 0.0
calcium ion binding Hs molecular function 1650 0.0
protein binding Hs molecular function 1650 0.0
nucleus Hs cellular component 864 0.0
cytoplasm Hs cellular component 864 0.0
lysosome Hs cellular component 801 0.0
lysosomal membrane Hs cellular component 864 0.0
endosome Hs cellular component 864 0.0
early endosome Hs cellular component 864 0.0
endoplasmic reticulum Hs cellular component 801 0.0
Golgi apparatus Hs cellular component 801 0.0
plasma membrane Hs cellular component 1650 0.0
integral component of plasma membrane Hs cellular component 864 0.0
brush border Hs cellular component 801 0.0
clathrin-coated pit Hs cellular component 864 0.0
focal adhesion Hs cellular component 864 0.0
drug binding Hs molecular function 801 0.0
external side of plasma membrane Hs cellular component 801 0.0
cell surface Hs cellular component 1650 0.0
postsynaptic density Hs cellular component 1650 0.0
membrane Hs cellular component 1650 0.0
integral component of membrane Hs cellular component 1650 0.0
basolateral plasma membrane Hs cellular component 864 0.0
apical plasma membrane Hs cellular component 801 0.0
flotillin complex Hs cellular component 1650 0.0
alpha-2 macroglobulin receptor activity Hs molecular function 864 0.0
SH3 domain binding Hs molecular function 801 0.0
Wnt-protein binding Hs molecular function 1650 0.0
clathrin-coated vesicle Hs cellular component 864 0.0
endocytic vesicle Hs cellular component 801 0.0
apolipoprotein receptor activity Hs molecular function 864 0.0
axon Hs cellular component 801 0.0
dendrite Hs cellular component 1650 0.0
clathrin-coated vesicle membrane Hs cellular component 801 0.0
endocytic vesicle membrane Hs cellular component 864 0.0
receptor tyrosine kinase binding Hs molecular function 1650 0.0
brush border membrane Hs cellular component 801 0.0
neuromuscular junction Hs cellular component 1650 0.0
endosome lumen Hs cellular component 801 0.0
clathrin heavy chain binding Hs molecular function 864 0.0
apolipoprotein binding Hs molecular function 1650 0.0
steroid hormone receptor binding Hs molecular function 801 0.0
protein homodimerization activity Hs molecular function 1650 0.0
Wnt-activated receptor activity Hs molecular function 1650 0.0
lipoprotein transporter activity Hs molecular function 864 0.0
cell projection Hs cellular component 801 0.0
neuronal cell body Hs cellular component 1650 0.0
receptor complex Hs cellular component 1650 0.0
heparan sulfate proteoglycan binding Hs molecular function 864 0.0
macromolecular complex binding Hs molecular function 864 0.0
apical part of cell Hs cellular component 801 0.0
metal ion binding Hs molecular function 864 0.0
chaperone binding Hs molecular function 801 0.0
extracellular exosome Hs cellular component 801 0.0
lipoprotein particle receptor binding Hs molecular function 864 0.0
synaptic membrane Hs cellular component 1650 0.0
scaffold protein binding Hs molecular function 1650 0.0
plasma membrane protein complex Hs cellular component 864 0.0

GO (InterProScan)

5 results

GO Term Analysis Type e-value
calcium ion binding SMART molecular function 9.9E-9
protein binding PRINTS molecular function 3.2E-53
BMP signaling pathway PANTHER biological process 0.0
animal organ development PANTHER biological process 0.0
regulation of canonical Wnt signaling pathway PANTHER biological process 0.0