Aniseed - Gene card

Gene Card

Best human hits

LRP1; LRP2; LRP4

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00006418

Gene Model ID

KH2012:KH.C4.335

Location

KhC4:418784..439480

Transcript Models and Sequences

KH2012:KH.C4.335.v1.A.SL1-1
KH2012:KH.C4.335.v1.A.SL2-1
KH2012:KH.C4.335.v1.A.SL3-1
KH2012:KH.C4.335.v2.A.SL1-2
KH2012:KH.C4.335.v2.A.SL2-2
KH2012:KH.C4.335.v2.A.SL3-2

External Database Gene Card

External database links

6 results

Database	Gene ID
ENSEMBL	ENSCING00000005450
ENSEMBL	ENSCING00000020552
ENSEMBL	ENSCING00000022067
ENSEMBL	ENSCING00000024837
NCBI Reference Sequence	XM_018811459.1
NCBI Reference Sequence	XM_018811460.1

Collections

Gateway full ORF

2 results

Gene collection 1 (N. Satoh)

2 results

citb038a22

Plate: R1CiGC32b23

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

19 results

IPR Term	Analysis	Definition
LDrepeatLR_classA_rpt	CDD	Low-density lipoprotein (LDL) receptor class A repeat
LDrepeatLR_classA_rpt	ProSiteProfiles	Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt	ProSiteProfiles	LDLR class B repeat
6-blade_b-propeller_TolB-like	Gene3D	Six-bladed beta-propeller, TolB-like
LDLR_class-A_CS	ProSitePatterns	Low-density lipoprotein (LDL) receptor class A, conserved site
EGF-like_CS	ProSitePatterns	EGF-like, conserved site
EGF-like_Ca-bd_dom	SMART	EGF-like calcium-binding domain
LDL_receptor-like_sf	SUPERFAMILY	LDL receptor-like superfamily
LRP4	PANTHER	Low-density lipoprotein receptor-related protein 4
LDLR_classB_rpt	Pfam	LDLR class B repeat
LDrepeatLR_classA_rpt	PRINTS	Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_dom	SMART	EGF-like domain
LDrepeatLR_classA_rpt	SMART	Low-density lipoprotein (LDL) receptor class A repeat
EGF_Ca-bd_CS	ProSitePatterns	EGF-like calcium-binding, conserved site
LDLR_classB_rpt	SMART	LDLR class B repeat
Growth_fac_rcpt_cys_sf	SUPERFAMILY	Growth factor receptor cysteine-rich domain superfamily
LDrepeatLR_classA_rpt	Pfam	Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_Ca-bd_dom	Pfam	EGF-like calcium-binding domain
EGF-type_Asp/Asn_hydroxyl_site	ProSitePatterns	EGF-type aspartate/asparagine hydroxylation site

GOSlim

78 results

GO Term	Annotation Origin	Type
RNA binding	Blast	molecular function
calcium ion binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Blast	cellular component
cytoplasm	Blast	cellular component
lysosome	Blast	cellular component
lysosomal membrane	Blast	cellular component
endosome	Blast	cellular component
early endosome	Blast	cellular component
endoplasmic reticulum	Blast	cellular component
Golgi apparatus	Blast	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Blast	cellular component
brush border	Blast	cellular component
focal adhesion	Blast	cellular component
multicellular organism development	Orthology	biological process
nervous system development	Orthology	biological process
protein localization	Orthology	biological process
cell surface	Orthology	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
basolateral plasma membrane	Blast	cellular component
apical plasma membrane	Blast	cellular component
cell differentiation	Orthology	biological process
negative regulation of Wnt signaling pathway	Orthology	biological process
axon	Blast	cellular component
brush border membrane	Blast	cellular component
protein homodimerization activity	Orthology	molecular function
cell projection	Blast	cellular component
neuronal cell body	Orthology	cellular component
macromolecular complex binding	Blast	molecular function
apical part of cell	Blast	cellular component
metal ion binding	Blast	molecular function
animal organ development	Orthology	biological process
anatomical structure development	Orthology	biological process
regulation of canonical Wnt signaling pathway	Orthology	biological process
membrane organization	Orthology	biological process
extracellular exosome	Blast	cellular component
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
synaptic membrane	Orthology	cellular component
regulation of cellular metabolic process	Orthology	biological process
protein phosphorylation	Orthology	biological process
organelle organization	Orthology	biological process
organelle	Orthology	cellular component
postsynapse	Orthology	cellular component
neuron part	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
plasma membrane region	Orthology	cellular component
membrane raft	Orthology	cellular component
macromolecular complex	Orthology	cellular component
anatomical structure morphogenesis	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cellular response to organic substance	Orthology	biological process
receptor binding	Orthology	molecular function
protein kinase binding	Orthology	molecular function
synapse	Orthology	cellular component
transmembrane signaling receptor activity	Orthology	molecular function
protein localization to membrane	Orthology	biological process
cell morphogenesis involved in neuron differentiation	Orthology	biological process
neuron projection morphogenesis	Orthology	biological process
axonogenesis	Orthology	biological process
cellular component organization	Orthology	biological process
protein oligomerization	Orthology	biological process
enzyme binding	Blast	molecular function
membrane part	Blast	cellular component
endomembrane system	Blast	cellular component
binding	Blast	molecular function
plasma membrane part	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
intracellular organelle part	Blast	cellular component
whole membrane	Blast	cellular component
bounding membrane of organelle	Blast	cellular component
intracellular organelle lumen	Blast	cellular component
transcription factor binding	Blast	molecular function
protein transport	Blast	biological process
anion binding	Blast	molecular function
carbohydrate derivative binding	Blast	molecular function

GO (Orthology)

49 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
kidney development	Hs	biological process
regulation of protein phosphorylation	Hs	biological process
calcium ion binding	Hs	molecular function
protein binding	Hs	molecular function
plasma membrane	Hs	cellular component
endocytosis	Hs	biological process
multicellular organism development	Hs	biological process
protein localization	Hs	biological process
dorsal/ventral pattern formation	Hs	biological process
proximal/distal pattern formation	Hs	biological process
cell surface	Hs	cellular component
postsynaptic density	Hs	cellular component
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
Wnt signaling pathway	Hs	biological process
flotillin complex	Hs	cellular component
Wnt-protein binding	Hs	molecular function
cell differentiation	Hs	biological process
negative regulation of Wnt signaling pathway	Hs	biological process
negative regulation of ossification	Hs	biological process
embryonic limb morphogenesis	Hs	biological process
dendrite	Hs	cellular component
BMP signaling pathway	Hs	biological process
receptor tyrosine kinase binding	Hs	molecular function
neuromuscular junction	Hs	cellular component
apolipoprotein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
Wnt-activated receptor activity	Hs	molecular function
neuronal cell body	Hs	cellular component
receptor clustering	Hs	biological process
receptor complex	Hs	cellular component
Wnt signaling pathway involved in dorsal/ventral axis specification	Hs	biological process
animal organ development	Hs	biological process
dendrite morphogenesis	Hs	biological process
anatomical structure development	Hs	biological process
positive regulation of peptidyl-tyrosine phosphorylation	Hs	biological process
negative regulation of axonogenesis	Hs	biological process
synapse organization	Hs	biological process
synaptic growth at neuromuscular junction	Hs	biological process
protein heterotetramerization	Hs	biological process
limb development	Hs	biological process
regulation of canonical Wnt signaling pathway	Hs	biological process
skeletal muscle acetylcholine-gated channel clustering	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
synaptic membrane	Hs	cellular component
postsynaptic membrane assembly	Hs	biological process
presynaptic membrane assembly	Hs	biological process
scaffold protein binding	Hs	molecular function
positive regulation of skeletal muscle acetylcholine-gated channel clustering	Hs	biological process

GO (Blast)

62 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score
protease binding	Hs	molecular function	864
RNA binding	Hs	molecular function	864
receptor activity	Hs	molecular function	864
low-density lipoprotein receptor activity	Hs	molecular function	864
scavenger receptor activity	Hs	molecular function	864
calcium ion binding	Hs	molecular function	1650
protein binding	Hs	molecular function	1650
nucleus	Hs	cellular component	864
cytoplasm	Hs	cellular component	864
lysosome	Hs	cellular component	801
lysosomal membrane	Hs	cellular component	864
endosome	Hs	cellular component	864
early endosome	Hs	cellular component	864
endoplasmic reticulum	Hs	cellular component	801
Golgi apparatus	Hs	cellular component	801
plasma membrane	Hs	cellular component	1650
integral component of plasma membrane	Hs	cellular component	864
brush border	Hs	cellular component	801
clathrin-coated pit	Hs	cellular component	864
focal adhesion	Hs	cellular component	864
drug binding	Hs	molecular function	801
external side of plasma membrane	Hs	cellular component	801
cell surface	Hs	cellular component	1650
postsynaptic density	Hs	cellular component	1650
membrane	Hs	cellular component	1650
integral component of membrane	Hs	cellular component	1650
basolateral plasma membrane	Hs	cellular component	864
apical plasma membrane	Hs	cellular component	801
flotillin complex	Hs	cellular component	1650
alpha-2 macroglobulin receptor activity	Hs	molecular function	864
SH3 domain binding	Hs	molecular function	801
Wnt-protein binding	Hs	molecular function	1650
clathrin-coated vesicle	Hs	cellular component	864
endocytic vesicle	Hs	cellular component	801
apolipoprotein receptor activity	Hs	molecular function	864
axon	Hs	cellular component	801
dendrite	Hs	cellular component	1650
clathrin-coated vesicle membrane	Hs	cellular component	801
endocytic vesicle membrane	Hs	cellular component	864
receptor tyrosine kinase binding	Hs	molecular function	1650
brush border membrane	Hs	cellular component	801
neuromuscular junction	Hs	cellular component	1650
endosome lumen	Hs	cellular component	801
clathrin heavy chain binding	Hs	molecular function	864
apolipoprotein binding	Hs	molecular function	1650
steroid hormone receptor binding	Hs	molecular function	801
protein homodimerization activity	Hs	molecular function	1650
Wnt-activated receptor activity	Hs	molecular function	1650
lipoprotein transporter activity	Hs	molecular function	864
cell projection	Hs	cellular component	801
neuronal cell body	Hs	cellular component	1650
receptor complex	Hs	cellular component	1650
heparan sulfate proteoglycan binding	Hs	molecular function	864
macromolecular complex binding	Hs	molecular function	864
apical part of cell	Hs	cellular component	801
metal ion binding	Hs	molecular function	864
chaperone binding	Hs	molecular function	801
extracellular exosome	Hs	cellular component	801
lipoprotein particle receptor binding	Hs	molecular function	864
synaptic membrane	Hs	cellular component	1650
scaffold protein binding	Hs	molecular function	1650
plasma membrane protein complex	Hs	cellular component	864

GO (InterProScan)

5 results

GO Term	Analysis	Type	e-value
calcium ion binding	SMART	molecular function	9.9E-9
protein binding	PRINTS	molecular function	3.2E-53
BMP signaling pathway	PANTHER	biological process	0.0
animal organ development	PANTHER	biological process	0.0
regulation of canonical Wnt signaling pathway	PANTHER	biological process	0.0