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GENE CARD

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  1. Gene 'Phmamm.CG.MTP2014.S2...' > 
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Gene Card

Best human hits

SIRT4; SIRT6; SIRT7

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00005432

Gene Model ID

KH2012:KH.C3.266

Location

KhC3:5810181..5814059

Transcript Models and Sequences

  KH2012:KH.C3.266.v1.A.SL1-1

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000022308
Collections

Gateway full ORF

2 results

cien36312

Plate: VES76_F03

cien37157

Plate: VES76_M05

Gene collection 1 (N. Satoh)

1 result

cieg028o23

Plate: R1CiGC20o23

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

3 results

IPR Term Analysis Definition
DHS-like_NAD/FAD-binding_dom SUPERFAMILY DHS-like NAD/FAD-binding domain superfamily
Sirtuin Pfam Sirtuin family
Ssirtuin_cat_dom ProSiteProfiles Sirtuin family, catalytic core domain

GOSlim

25 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
chromatin binding Orthology molecular function
transcription corepressor activity Blast molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Blast cellular component
nucleolus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
mitochondrial inner membrane Blast cellular component
mitochondrial matrix Blast cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
zinc ion binding Blast molecular function
transferase activity Blast molecular function
hydrolase activity Orthology molecular function
metal ion binding Orthology molecular function
macromolecular complex Orthology cellular component
organelle organization Orthology biological process
anion binding Orthology molecular function
nucleotide binding Orthology molecular function
coenzyme binding Orthology molecular function
cellular protein modification process Orthology biological process
intracellular non-membrane-bounded organelle Blast cellular component
nuclear lumen Blast cellular component

GO (Orthology)

16 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
chromatin binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleolus Hs cellular component
nucleolus organizer region Hs cellular component
cytoplasm Hs cellular component
chromatin organization Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
rRNA transcription Hs biological process
hydrolase activity Hs molecular function
metal ion binding Hs molecular function
NAD+ binding Hs molecular function
histone H3 deacetylation Hs biological process
NAD-dependent histone deacetylase activity (H3-K18 specific) Hs molecular function

GO (Blast)

26 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
chromatin binding Hs molecular function 329 8.27e-109
transcription corepressor activity Hs molecular function 171 8.60e-49
NAD+ ADP-ribosyltransferase activity Hs molecular function 171 8.60e-49
NAD(P)+-protein-arginine ADP-ribosyltransferase activity Hs molecular function 171 8.60e-49
protein binding Hs molecular function 329 8.27e-109
nucleus Hs cellular component 329 8.27e-109
nucleoplasm Hs cellular component 171 8.60e-49
nuclear telomeric heterochromatin Hs cellular component 171 8.60e-49
nucleolus Hs cellular component 329 8.27e-109
nucleolus organizer region Hs cellular component 329 8.27e-109
cytoplasm Hs cellular component 329 8.27e-109
mitochondrion Hs cellular component 72.4 7.04e-14
mitochondrial inner membrane Hs cellular component 72.4 7.04e-14
mitochondrial matrix Hs cellular component 72.4 7.04e-14
zinc ion binding Hs molecular function 171 8.60e-49
transferase activity Hs molecular function 72.4 7.04e-14
hydrolase activity Hs molecular function 329 8.27e-109
NAD-dependent histone deacetylase activity Hs molecular function 171 8.60e-49
protein deacetylase activity Hs molecular function 171 8.60e-49
NAD-dependent protein deacetylase activity Hs molecular function 171 8.60e-49
metal ion binding Hs molecular function 329 8.27e-109
NAD-dependent histone deacetylase activity (H3-K9 specific) Hs molecular function 171 8.60e-49
biotinidase activity Hs molecular function 72.4 7.04e-14
lipoamidase activity Hs molecular function 72.4 7.04e-14
NAD+ binding Hs molecular function 329 8.27e-109
NAD-dependent histone deacetylase activity (H3-K18 specific) Hs molecular function 329 8.27e-109

GO (InterProScan)

1 result

GO Term Analysis Type e-value
NAD+ binding Pfam molecular function 1.4E-19

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