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GENE CARD

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Gene Card

Best human hits

E2F2; E2F3

Unique Gene ID

Cirobu.g00005056

Gene Model ID

KH2012:KH.C2.822

Location

KhC2:6028778..6034282

External Database Gene Card

External database links

2 results

Collections

Gateway full ORF

2 results

cien81675

Plate: VES83_J03

cien145806

Plate: VES93_I01

Gene collection 1 (N. Satoh)

3 results

cicl012m24

Plate: R1CiGC09f20

cieg020g18

Plate: R1CiGC18p07

cicl051e11

Plate: R1CiGC14a03

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
E2F_CC-MB CDD E2F transcription factor, CC-MB domain
E2F_CC-MB Pfam E2F transcription factor, CC-MB domain
E2F_WHTH_DNA-bd_dom Pfam E2F/DP family, winged-helix DNA-binding domain
WH_DNA-bd_sf SUPERFAMILY Winged helix DNA-binding domain superfamily
E2F_WHTH_DNA-bd_dom SMART E2F/DP family, winged-helix DNA-binding domain
WH-like_DNA-bd_sf Gene3D Winged helix-like DNA-binding domain superfamily
E2F PANTHER E2F Family
E2F-DP_heterodim SUPERFAMILY E2F-DP heterodimerization region

GOSlim

43 results

GO Term Annotation Origin Type
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
cell cycle Orthology biological process
transcription factor binding Orthology molecular function
positive regulation of cell proliferation Orthology biological process
sequence-specific DNA binding Orthology molecular function
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
protein dimerization activity Orthology molecular function
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
centrosome Orthology cellular component
apoptotic process Orthology biological process
spermatogenesis Orthology biological process
positive regulation of gene expression Orthology biological process
protein kinase binding Orthology molecular function
macromolecular complex Orthology cellular component
positive regulation of apoptotic process Orthology biological process
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
intracellular part Orthology cellular component
intracellular signal transduction Orthology biological process
nuclear part Orthology cellular component
angiogenesis Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
brain development Orthology biological process
regulation of molecular function Orthology biological process
mRNA catabolic process Orthology biological process
response to hypoxia Orthology biological process
cellular response to stress Orthology biological process
G1/S transition of mitotic cell cycle Orthology biological process

GO (Orthology)

48 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
core promoter binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
cell cycle Hs biological process
transcription factor binding Hs molecular function
positive regulation of cell proliferation Hs biological process
sequence-specific DNA binding Hs molecular function
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
protein dimerization activity Hs molecular function
regulation of cell cycle Hs biological process
intrinsic apoptotic signaling pathway by p53 class mediator Hs biological process
RNA polymerase II transcription factor complex Hs cellular component
negative regulation of sprouting angiogenesis Hs biological process
DNA damage checkpoint Hs biological process
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear chromatin Hs cellular component
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
cytoplasm Hs cellular component
mitochondrion Hs cellular component
centrosome Hs cellular component
apoptotic process Hs biological process
spermatogenesis Hs biological process
intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
positive regulation of gene expression Hs biological process
protein kinase binding Hs molecular function
forebrain development Hs biological process
macromolecular complex Hs cellular component
Rb-E2F complex Hs cellular component
positive regulation of apoptotic process Hs biological process
negative regulation of DNA binding Hs biological process
transcription regulatory region DNA binding Hs molecular function
negative regulation of transcription, DNA-templated Hs biological process
mRNA stabilization Hs biological process
cellular response to hypoxia Hs biological process
cellular response to xenobiotic stimulus Hs biological process
negative regulation of transcription involved in G1/S transition of mitotic cell cycle Hs biological process
regulation of G1/S transition of mitotic cell cycle Hs biological process

GO (Blast)

14 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 235 1.32e-72
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 235 1.32e-72
core promoter binding Hs molecular function 235 1.32e-72
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 235 1.32e-72
DNA binding Hs molecular function 235 1.32e-72
transcription factor activity, sequence-specific DNA binding Hs molecular function 235 1.32e-72
protein binding Hs molecular function 235 1.32e-72
nucleus Hs cellular component 235 1.32e-72
nucleoplasm Hs cellular component 235 1.32e-72
transcription factor complex Hs cellular component 235 1.32e-72
transcription factor binding Hs molecular function 225 4.08e-69
sequence-specific DNA binding Hs molecular function 235 1.32e-72
protein dimerization activity Hs molecular function 235 1.32e-72
RNA polymerase II transcription factor complex Hs cellular component 235 1.32e-72

GO (InterProScan)

4 results

GO Term Analysis Type e-value
transcription factor activity, sequence-specific DNA binding SMART molecular function 3.2E-33
transcription factor complex SMART cellular component 3.2E-33
regulation of transcription, DNA-templated SMART biological process 3.2E-33
protein dimerization activity CDD molecular function 2.50263E-42