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GENE CARD

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Gene Card

Best human hits

FGFR1; FGFR2; FGFR3

Unique Gene ID

Cirobu.g00005032

Gene Model ID

KH2012:KH.C2.800

Location

KhC2:5257419..5262870

Collections
WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Ig-like_dom ProSiteProfiles Immunoglobulin-like domain
Tyr_kinase_AS ProSitePatterns Tyrosine-protein kinase, active site
Ig_sub SMART Immunoglobulin subtype
Ser-Thr/Tyr_kinase_cat_dom Pfam Serine-threonine/tyrosine-protein kinase, catalytic domain
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily
Tyr_kinase_cat_dom SMART Tyrosine-protein kinase, catalytic domain
Ig-like_fold Gene3D Immunoglobulin-like fold
Ig-like_dom_sf SUPERFAMILY Immunoglobulin-like domain superfamily
Ser-Thr/Tyr_kinase_cat_dom PRINTS Serine-threonine/tyrosine-protein kinase, catalytic domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site

GOSlim

42 results

GO Term Annotation Origin Type
nucleotide binding Blast molecular function
protein kinase activity Blast molecular function
protein binding Blast molecular function
ATP binding Blast molecular function
extracellular region Blast cellular component
nucleus Blast cellular component
nucleoplasm Blast cellular component
nucleolus Blast cellular component
cytoplasm Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
cytosol Blast cellular component
plasma membrane Blast cellular component
integral component of plasma membrane Blast cellular component
focal adhesion Blast cellular component
protein phosphorylation InterProScan biological process
cell surface Blast cellular component
membrane Blast cellular component
integral component of membrane Blast cellular component
kinase activity Blast molecular function
transferase activity Blast molecular function
cytoplasmic vesicle Blast cellular component
identical protein binding Blast molecular function
protein homodimerization activity Blast molecular function
intracellular membrane-bounded organelle Blast cellular component
transmembrane signaling receptor activity Blast molecular function
cell surface receptor signaling pathway Blast biological process
cellular response to organic substance Blast biological process
enzyme binding Blast molecular function
molecular function regulator Blast molecular function
cell periphery Blast cellular component
cytoplasmic part Blast cellular component
anion binding Blast molecular function
carbohydrate derivative binding Blast molecular function
phosphotransferase activity, alcohol group as acceptor Blast molecular function
cellular biosynthetic process Blast biological process
endomembrane system Blast cellular component
extracellular region part Blast cellular component
macromolecular complex Blast cellular component
organic substance metabolic process Blast biological process
synapse Blast cellular component
receptor binding Blast molecular function

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 218 1.09e-61
protein kinase activity Hs molecular function 218 1.09e-61
protein tyrosine kinase activity Hs molecular function 218 1.09e-61
transmembrane receptor protein tyrosine kinase activity Hs molecular function 218 1.09e-61
fibroblast growth factor-activated receptor activity Hs molecular function 218 1.09e-61
Ras guanyl-nucleotide exchange factor activity Hs molecular function 218 1.09e-61
protein binding Hs molecular function 218 1.09e-61
ATP binding Hs molecular function 218 1.09e-61
extracellular region Hs cellular component 218 1.09e-61
nucleus Hs cellular component 218 1.09e-61
nucleoplasm Hs cellular component 218 1.09e-61
nucleolus Hs cellular component 212 1.79e-59
cytoplasm Hs cellular component 218 1.09e-61
endoplasmic reticulum Hs cellular component 206 1.24e-57
Golgi apparatus Hs cellular component 218 1.09e-61
cytosol Hs cellular component 212 1.79e-59
plasma membrane Hs cellular component 218 1.09e-61
integral component of plasma membrane Hs cellular component 218 1.09e-61
focal adhesion Hs cellular component 206 1.24e-57
cell cortex Hs cellular component 218 1.09e-61
heparin binding Hs molecular function 218 1.09e-61
cell surface Hs cellular component 218 1.09e-61
membrane Hs cellular component 218 1.09e-61
integral component of membrane Hs cellular component 218 1.09e-61
kinase activity Hs molecular function 218 1.09e-61
1-phosphatidylinositol-3-kinase activity Hs molecular function 218 1.09e-61
transferase activity Hs molecular function 218 1.09e-61
fibroblast growth factor binding Hs molecular function 218 1.09e-61
transport vesicle Hs cellular component 206 1.24e-57
extracellular matrix Hs cellular component 218 1.09e-61
cytoplasmic vesicle Hs cellular component 218 1.09e-61
identical protein binding Hs molecular function 212 1.79e-59
protein homodimerization activity Hs molecular function 218 1.09e-61
intracellular membrane-bounded organelle Hs cellular component 218 1.09e-61
receptor complex Hs cellular component 212 1.79e-59
phosphatidylinositol-4,5-bisphosphate 3-kinase activity Hs molecular function 218 1.09e-61
excitatory synapse Hs cellular component 218 1.09e-61
receptor-receptor interaction Hs molecular function 212 1.79e-59

GO (InterProScan)

4 results

GO Term Analysis Type e-value
protein kinase activity Pfam molecular function 4.8E-73
protein tyrosine kinase activity SMART molecular function 1.0E-90
ATP binding ProSiteProfiles molecular function 34.916
protein phosphorylation SMART biological process 1.0E-90