Gene Card
Best human hits
SMAD1; SMAD5; SMAD9
Unique Gene ID
Cirobu.g00004785
Gene Model ID
KH2012:KH.C2.573
Location
KhC2:3201112..3212869
Transcript Models and Sequences
KH2012:KH.C2.573.v1.R.SL1-2
KH2012:KH.C2.573.v2.R.SL1-1
KH2012:KH.C2.573.v3.A.SL1-2
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000005942 |
ENSEMBL | ENSCING00000022875 |
NCBI Reference Sequence | NM_001078347.1 |
cien109309
Plate: VES87_A10
cima89470
Plate: VES57_F18
cima835044
Plate: VES62_M17
cien121231
Plate: VES89_G06
cicl016e21
Plate: R1CiGC10g18
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Dwarfin | PANTHER | Dwarfin |
SMAD-like_dom_sf | Gene3D | SMAD-like domain superfamily |
SMAD_dom_Dwarfin-type | ProSiteProfiles | SMAD domain, Dwarfin-type |
SMAD_dom_Dwarfin-type | SMART | SMAD domain, Dwarfin-type |
SMAD_dom_Dwarfin-type | Pfam | SMAD domain, Dwarfin-type |
SMAD_FHA_dom_sf | SUPERFAMILY | SMAD/FHA domain superfamily |
SMAD_MH1_sf | SUPERFAMILY | SMAD MH1 domain superfamily |
MAD_homology1_Dwarfin-type | SMART | MAD homology 1, Dwarfin-type |
MAD_homology1_Dwarfin-type | Pfam | MAD homology 1, Dwarfin-type |
MAD_homology_MH1 | ProSiteProfiles | MAD homology, MH1 |
SMAD_MH1_sf | Gene3D | SMAD MH1 domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
negative regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
RNA polymerase II regulatory region sequence-specific DNA binding | Orthology | molecular function |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Orthology | molecular function |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
DNA binding | Orthology | molecular function |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
transcription from RNA polymerase II promoter | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
signal transduction | Orthology | biological process |
gamete generation | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
positive regulation of gene expression | Orthology | biological process |
integral component of membrane | Orthology | cellular component |
protein kinase binding | Orthology | molecular function |
ubiquitin protein ligase binding | Orthology | molecular function |
macromolecular complex | Orthology | cellular component |
identical protein binding | Orthology | molecular function |
protein homodimerization activity | Orthology | molecular function |
sequence-specific DNA binding | Orthology | molecular function |
positive regulation of transcription, DNA-templated | Orthology | biological process |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
metal ion binding | Orthology | molecular function |
protein heterodimerization activity | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
animal organ development | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
multicellular organism development | Orthology | biological process |
cell differentiation | Orthology | biological process |
organelle inner membrane | Orthology | cellular component |
nuclear membrane | Orthology | cellular component |
intracellular part | Orthology | cellular component |
defense response | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
cell development | Orthology | biological process |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
immune system process | Orthology | biological process |
molecular transducer activity | Orthology | molecular function |
brain development | Orthology | biological process |
RNA processing | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
heart development | Orthology | biological process |
cell proliferation | Orthology | biological process |
RNA binding | Orthology | molecular function |
angiogenesis | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
RNA polymerase II regulatory region sequence-specific DNA binding | Hs | molecular function | 695 | 0.0 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 699 | 0.0 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 699 | 0.0 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | Hs | molecular function | 699 | 0.0 |
DNA binding | Hs | molecular function | 699 | 0.0 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 699 | 0.0 |
signal transducer activity, downstream of receptor | Hs | molecular function | 699 | 0.0 |
protein binding | Hs | molecular function | 699 | 0.0 |
intracellular | Hs | cellular component | 699 | 0.0 |
nucleus | Hs | cellular component | 699 | 0.0 |
nuclear inner membrane | Hs | cellular component | 699 | 0.0 |
nucleoplasm | Hs | cellular component | 699 | 0.0 |
transcription factor complex | Hs | cellular component | 699 | 0.0 |
cytoplasm | Hs | cellular component | 699 | 0.0 |
cytosol | Hs | cellular component | 699 | 0.0 |
integral component of membrane | Hs | cellular component | 699 | 0.0 |
DEAD/H-box RNA helicase binding | Hs | molecular function | 699 | 0.0 |
protein kinase binding | Hs | molecular function | 699 | 0.0 |
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity | Hs | molecular function | 699 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 695 | 0.0 |
macromolecular complex | Hs | cellular component | 699 | 0.0 |
identical protein binding | Hs | molecular function | 699 | 0.0 |
protein homodimerization activity | Hs | molecular function | 699 | 0.0 |
sequence-specific DNA binding | Hs | molecular function | 699 | 0.0 |
metal ion binding | Hs | molecular function | 699 | 0.0 |
protein heterodimerization activity | Hs | molecular function | 699 | 0.0 |
co-SMAD binding | Hs | molecular function | 699 | 0.0 |
I-SMAD binding | Hs | molecular function | 699 | 0.0 |
primary miRNA binding | Hs | molecular function | 699 | 0.0 |
SMAD protein complex | Hs | cellular component | 699 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
transcription factor activity, sequence-specific DNA binding | ProSiteProfiles | molecular function | 36.771 |
protein binding | SUPERFAMILY | molecular function | 1.06E-91 |
intracellular | PANTHER | cellular component | 6.9E-256 |
transcription factor complex | ProSiteProfiles | cellular component | 36.771 |
regulation of transcription, DNA-templated | PANTHER | biological process | 6.9E-256 |
transforming growth factor beta receptor signaling pathway | Gene3D | biological process | 4.1E-65 |