Gene Card
Best human hits
DUOX1; DUOX2; NOX1
Unique Gene ID
Cirobu.g00004678
Gene Model ID
KH2012:KH.C2.477
Location
KhC2:1624382..1635303
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000003977 |
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
EF_hand_dom | CDD | EF-hand domain |
EF_hand_dom | ProSiteProfiles | EF-hand domain |
DUOX1/Duox | PANTHER | Dual oxidase 1/Duox |
Haem_peroxidase_animal | Pfam | Haem peroxidase, animal type |
EF_hand_dom | Pfam | EF-hand domain |
FAD-bd_8 | Pfam | FAD-binding 8 |
EF-hand-dom_pair | SUPERFAMILY | EF-hand domain pair |
Haem_peroxidase_sf | Gene3D | Haem peroxidase domain superfamily, animal type |
Fe3_Rdtase_TM_dom | Pfam | Ferric reductase transmembrane component-like domain |
Fe_red_NAD-bd_6 | Pfam | Ferric reductase, NAD binding domain |
Haem_peroxidase | SUPERFAMILY | Haem peroxidase |
EF_hand_dom | SMART | EF-hand domain |
Riboflavin_synthase-like_b-brl | SUPERFAMILY | Riboflavin synthase-like beta-barrel |
Haem_peroxidase_animal | ProSiteProfiles | Haem peroxidase, animal type |
Fd_Rdtase_FAD-bd | ProSiteProfiles | Ferredoxin reductase-type FAD-binding domain |
EF_Hand_1_Ca_BS | ProSitePatterns | EF-Hand 1, calcium-binding site |
GO Term | Annotation Origin | Type |
---|---|---|
calcium ion binding | Blast | molecular function |
protein binding | Blast | molecular function |
cytoplasm | Blast | cellular component |
endosome | Blast | cellular component |
early endosome | Blast | cellular component |
plasma membrane | Blast | cellular component |
ion transport | Blast | biological process |
response to oxidative stress | InterProScan | biological process |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
apical plasma membrane | Blast | cellular component |
heme binding | Blast | molecular function |
cell junction | Blast | cellular component |
cell projection | Blast | cellular component |
metal ion binding | Blast | molecular function |
oxidation-reduction process | Blast | biological process |
extracellular exosome | Blast | cellular component |
catalytic activity | Blast | molecular function |
transmembrane transport | Blast | biological process |
integral component of plasma membrane | Blast | cellular component |
macromolecular complex | Blast | cellular component |
enzyme binding | Blast | molecular function |
nucleotide binding | Blast | molecular function |
coenzyme binding | Blast | molecular function |
cell projection membrane | Blast | cellular component |
cellular biosynthetic process | InterProScan | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
peroxidase activity | Hs | molecular function | 895 | 0.0 |
voltage-gated ion channel activity | Hs | molecular function | 242 | 6.55e-69 |
calcium ion binding | Hs | molecular function | 895 | 0.0 |
protein binding | Hs | molecular function | 242 | 6.55e-69 |
cytoplasm | Hs | cellular component | 242 | 6.55e-69 |
endosome | Hs | cellular component | 242 | 6.55e-69 |
early endosome | Hs | cellular component | 242 | 6.55e-69 |
plasma membrane | Hs | cellular component | 895 | 0.0 |
membrane | Hs | cellular component | 895 | 0.0 |
integral component of membrane | Hs | cellular component | 895 | 0.0 |
NAD(P)H oxidase activity | Hs | molecular function | 895 | 0.0 |
superoxide-generating NADPH oxidase activity | Hs | molecular function | 242 | 6.55e-69 |
apical plasma membrane | Hs | cellular component | 895 | 0.0 |
oxidoreductase activity | Hs | molecular function | 895 | 0.0 |
heme binding | Hs | molecular function | 895 | 0.0 |
cell junction | Hs | cellular component | 863 | 0.0 |
cell projection | Hs | cellular component | 242 | 6.55e-69 |
NADPH oxidase complex | Hs | cellular component | 242 | 6.55e-69 |
metal ion binding | Hs | molecular function | 895 | 0.0 |
Rac GTPase binding | Hs | molecular function | 242 | 6.55e-69 |
NADP binding | Hs | molecular function | 895 | 0.0 |
extracellular exosome | Hs | cellular component | 863 | 0.0 |
invadopodium membrane | Hs | cellular component | 242 | 6.55e-69 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
peroxidase activity | SUPERFAMILY | molecular function | 3.18E-49 |
calcium ion binding | CDD | molecular function | 1.5901E-9 |
response to oxidative stress | SUPERFAMILY | biological process | 3.18E-49 |
NAD(P)H oxidase activity | PANTHER | molecular function | 0.0 |
oxidoreductase activity | Pfam | molecular function | 4.1E-28 |
heme binding | SUPERFAMILY | molecular function | 3.18E-49 |
hydrogen peroxide biosynthetic process | PANTHER | biological process | 0.0 |
oxidation-reduction process | SUPERFAMILY | biological process | 3.18E-49 |