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GENE CARD

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Gene Card

Best human hits

DUOX1; DUOX2; NOX1

Unique Gene ID

Cirobu.g00004678

Gene Model ID

KH2012:KH.C2.477

Location

KhC2:1624382..1635303

Transcript Models and Sequences

  KH2012:KH.C2.477.v1.B.ND1-1

External Database Gene Card

External database links

1 result

Database Gene ID
ENSEMBL ENSCING00000003977
Collections

Gene collection 1 (N. Satoh)

3 results

cies003e09

Plate: R1CiGC41a21

ciht034i20

Plate: R1CiGC44c15

ciht038j23

Plate: R1CiGC44k17

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

16 results

IPR Term Analysis Definition
EF_hand_dom CDD EF-hand domain
EF_hand_dom ProSiteProfiles EF-hand domain
DUOX1/Duox PANTHER Dual oxidase 1/Duox
Haem_peroxidase_animal Pfam Haem peroxidase, animal type
EF_hand_dom Pfam EF-hand domain
FAD-bd_8 Pfam FAD-binding 8
EF-hand-dom_pair SUPERFAMILY EF-hand domain pair
Haem_peroxidase_sf Gene3D Haem peroxidase domain superfamily, animal type
Fe3_Rdtase_TM_dom Pfam Ferric reductase transmembrane component-like domain
Fe_red_NAD-bd_6 Pfam Ferric reductase, NAD binding domain
Haem_peroxidase SUPERFAMILY Haem peroxidase
EF_hand_dom SMART EF-hand domain
Riboflavin_synthase-like_b-brl SUPERFAMILY Riboflavin synthase-like beta-barrel
Haem_peroxidase_animal ProSiteProfiles Haem peroxidase, animal type
Fd_Rdtase_FAD-bd ProSiteProfiles Ferredoxin reductase-type FAD-binding domain
EF_Hand_1_Ca_BS ProSitePatterns EF-Hand 1, calcium-binding site

GOSlim

26 results

GO Term Annotation Origin Type
calcium ion binding Blast molecular function
protein binding Blast molecular function
cytoplasm Blast cellular component
endosome Blast cellular component
early endosome Blast cellular component
plasma membrane Blast cellular component
ion transport Blast biological process
response to oxidative stress InterProScan biological process
membrane Blast cellular component
integral component of membrane Blast cellular component
apical plasma membrane Blast cellular component
heme binding Blast molecular function
cell junction Blast cellular component
cell projection Blast cellular component
metal ion binding Blast molecular function
oxidation-reduction process Blast biological process
extracellular exosome Blast cellular component
catalytic activity Blast molecular function
transmembrane transport Blast biological process
integral component of plasma membrane Blast cellular component
macromolecular complex Blast cellular component
enzyme binding Blast molecular function
nucleotide binding Blast molecular function
coenzyme binding Blast molecular function
cell projection membrane Blast cellular component
cellular biosynthetic process InterProScan biological process

GO (Orthology)

No result

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type

GO (Blast)

23 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
peroxidase activity Hs molecular function 895 0.0
voltage-gated ion channel activity Hs molecular function 242 6.55e-69
calcium ion binding Hs molecular function 895 0.0
protein binding Hs molecular function 242 6.55e-69
cytoplasm Hs cellular component 242 6.55e-69
endosome Hs cellular component 242 6.55e-69
early endosome Hs cellular component 242 6.55e-69
plasma membrane Hs cellular component 895 0.0
membrane Hs cellular component 895 0.0
integral component of membrane Hs cellular component 895 0.0
NAD(P)H oxidase activity Hs molecular function 895 0.0
superoxide-generating NADPH oxidase activity Hs molecular function 242 6.55e-69
apical plasma membrane Hs cellular component 895 0.0
oxidoreductase activity Hs molecular function 895 0.0
heme binding Hs molecular function 895 0.0
cell junction Hs cellular component 863 0.0
cell projection Hs cellular component 242 6.55e-69
NADPH oxidase complex Hs cellular component 242 6.55e-69
metal ion binding Hs molecular function 895 0.0
Rac GTPase binding Hs molecular function 242 6.55e-69
NADP binding Hs molecular function 895 0.0
extracellular exosome Hs cellular component 863 0.0
invadopodium membrane Hs cellular component 242 6.55e-69

GO (InterProScan)

8 results

GO Term Analysis Type e-value
peroxidase activity SUPERFAMILY molecular function 3.18E-49
calcium ion binding CDD molecular function 1.5901E-9
response to oxidative stress SUPERFAMILY biological process 3.18E-49
NAD(P)H oxidase activity PANTHER molecular function 0.0
oxidoreductase activity Pfam molecular function 4.1E-28
heme binding SUPERFAMILY molecular function 3.18E-49
hydrogen peroxide biosynthetic process PANTHER biological process 0.0
oxidation-reduction process SUPERFAMILY biological process 3.18E-49