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  1. Gene 'KH2012:KH.C10.289' > 
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  3. Gene 'KH2012:KH.C9.387' > 
  4. Gene 'KH2012:KH.L42.1' > 

Gene Card

Best human hits

SFRP1; SFRP2; SFRP5

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00004669

Gene Model ID

KH2012:KH.C2.469

Location

KhC2:5468395..5471691

Transcript Models and Sequences

  KH2012:KH.C2.469.v1.A.SL1-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000005178
NCBI Reference Sequence NM_001078536.1
Collections

Gateway full ORF

2 results

cima811121

Plate: VES57_P24

cima879561

Plate: VES68_O13

Gene collection 1 (N. Satoh)

1 result

citb5l2

Plate: R1CiGC29o12

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
Frizzled/SFRP PANTHER Frizzled/secreted frizzled-related protein
TIMP-like_OB-fold SUPERFAMILY Tissue inhibitor of metalloproteinases-like, OB-fold
SFRP2 PANTHER Secreted frizzled-related protein 2
Frizzled_dom_sf Gene3D Frizzled cysteine-rich domain superfamily
Frizzled_dom_sf SUPERFAMILY Frizzled cysteine-rich domain superfamily
Frizzled_dom SMART Frizzled domain
Netrin_module_non-TIMP Pfam Netrin module, non-TIMP type
Frizzled_dom Pfam Frizzled domain
Netrin_domain ProSiteProfiles Netrin domain
Frizzled_dom ProSiteProfiles Frizzled domain

GOSlim

72 results

GO Term Annotation Origin Type
G-protein coupled receptor activity Orthology molecular function
integrin binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
intracellular Blast cellular component
cytosol Blast cellular component
plasma membrane Blast cellular component
apoptotic process Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
cell-cell signaling Orthology biological process
multicellular organism development Orthology biological process
enzyme activator activity Orthology molecular function
positive regulation of cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
anatomical structure morphogenesis Orthology biological process
cell surface Blast cellular component
negative regulation of gene expression Orthology biological process
integral component of membrane Orthology cellular component
regulation of Wnt signaling pathway Orthology biological process
cell differentiation Orthology biological process
negative regulation of Wnt signaling pathway Orthology biological process
regulation of cell proliferation Orthology biological process
identical protein binding Blast molecular function
regulation of apoptotic process Orthology biological process
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
extracellular exosome Blast cellular component
negative regulation of canonical Wnt signaling pathway Orthology biological process
positive regulation of canonical Wnt signaling pathway Orthology biological process
angiogenesis Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
nervous system development Orthology biological process
animal organ development Orthology biological process
cell development Orthology biological process
heart development Orthology biological process
reproductive process Orthology biological process
regulation of molecular function Orthology biological process
regulation of signal transduction Orthology biological process
signaling receptor activity Orthology molecular function
endopeptidase activity Orthology molecular function
positive regulation of hydrolase activity Orthology biological process
neuron projection development Orthology biological process
cell surface receptor signaling pathway Orthology biological process
extracellular matrix organization Orthology biological process
cellular component organization Orthology biological process
cell migration Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to organic substance Orthology biological process
negative regulation of signal transduction Orthology biological process
extracellular region part Orthology cellular component
cell communication Orthology biological process
protein phosphorylation Orthology biological process
cell adhesion Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
cellular response to stress Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
receptor binding Orthology molecular function
molecular function regulator Orthology molecular function
system development Orthology biological process
enzyme binding Orthology molecular function
cell proliferation Orthology biological process
immune system process Orthology biological process
cell division Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
binding Blast molecular function
anion binding Blast molecular function
carbohydrate derivative binding Blast molecular function

GO (Orthology)

78 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
branching involved in blood vessel morphogenesis Hs biological process
somitogenesis Hs biological process
neural tube closure Hs biological process
fibronectin binding Hs molecular function
chondrocyte development Hs biological process
outflow tract morphogenesis Hs biological process
G-protein coupled receptor activity Hs molecular function
integrin binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
apoptotic process Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
cell-cell signaling Hs biological process
multicellular organism development Hs biological process
response to nutrient Hs biological process
enzyme activator activity Hs molecular function
positive regulation of cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
male gonad development Hs biological process
anterior/posterior pattern specification Hs biological process
regulation of receptor activity Hs biological process
negative regulation of gene expression Hs biological process
negative regulation of cardiac muscle cell apoptotic process Hs biological process
negative regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of endopeptidase activity Hs biological process
regulation of neuron projection development Hs biological process
integral component of membrane Hs cellular component
Wnt signaling pathway Hs biological process
Wnt-protein binding Hs molecular function
neural tube development Hs biological process
regulation of Wnt signaling pathway Hs biological process
cell differentiation Hs biological process
negative regulation of Wnt signaling pathway Hs biological process
collagen fibril organization Hs biological process
positive regulation of cell growth Hs biological process
negative regulation of cell growth Hs biological process
negative regulation of cell migration Hs biological process
negative regulation of BMP signaling pathway Hs biological process
extracellular matrix Hs cellular component
cellular response to extracellular stimulus Hs biological process
positive regulation of peptidyl-serine phosphorylation Hs biological process
positive regulation of cell adhesion mediated by integrin Hs biological process
non-canonical Wnt signaling pathway Hs biological process
post-anal tail morphogenesis Hs biological process
regulation of cell proliferation Hs biological process
response to drug Hs biological process
negative regulation of mesodermal cell fate specification Hs biological process
Wnt-activated receptor activity Hs molecular function
regulation of apoptotic process Hs biological process
positive regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
negative regulation of JUN kinase activity Hs biological process
positive regulation of fat cell differentiation Hs biological process
positive regulation of osteoblast differentiation Hs biological process
positive regulation of angiogenesis Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
development of primary male sexual characteristics Hs biological process
receptor ligand activity Hs molecular function
digestive tract morphogenesis Hs biological process
negative regulation of epithelial cell proliferation Hs biological process
negative regulation of peptidyl-tyrosine phosphorylation Hs biological process
cartilage development Hs biological process
convergent extension involved in axis elongation Hs biological process
bone morphogenesis Hs biological process
sclerotome development Hs biological process
endopeptidase activator activity Hs molecular function
hematopoietic stem cell proliferation Hs biological process
cellular response to X-ray Hs biological process
negative regulation of canonical Wnt signaling pathway Hs biological process
regulation of establishment of planar polarity Hs biological process
planar cell polarity pathway involved in neural tube closure Hs biological process
Wnt signaling pathway involved in somitogenesis Hs biological process
positive regulation of canonical Wnt signaling pathway Hs biological process
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors Hs biological process
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Hs biological process
regulation of stem cell division Hs biological process

GO (Blast)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
fibronectin binding Hs molecular function 215 7.37e-69
cysteine-type endopeptidase activity Hs molecular function 151 9.68e-44
G-protein coupled receptor activity Hs molecular function 215 7.37e-69
frizzled binding Hs molecular function 151 9.68e-44
integrin binding Hs molecular function 215 7.37e-69
protein binding Hs molecular function 215 7.37e-69
extracellular region Hs cellular component 215 7.37e-69
proteinaceous extracellular matrix Hs cellular component 151 9.68e-44
extracellular space Hs cellular component 215 7.37e-69
intracellular Hs cellular component 151 9.68e-44
cytosol Hs cellular component 151 9.68e-44
plasma membrane Hs cellular component 151 9.68e-44
enzyme activator activity Hs molecular function 215 7.37e-69
drug binding Hs molecular function 151 9.68e-44
heparin binding Hs molecular function 151 9.68e-44
cell surface Hs cellular component 151 9.68e-44
integral component of membrane Hs cellular component 215 7.37e-69
Wnt-protein binding Hs molecular function 215 7.37e-69
extracellular matrix Hs cellular component 215 7.37e-69
identical protein binding Hs molecular function 151 9.68e-44
Wnt-activated receptor activity Hs molecular function 215 7.37e-69
receptor ligand activity Hs molecular function 215 7.37e-69
endopeptidase activator activity Hs molecular function 215 7.37e-69
extracellular exosome Hs cellular component 151 9.68e-44

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding SMART molecular function 2.2E-45

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