Gene Card
Best human hits
KLHL12; RIPK1; RIPK3
Unique Gene ID
Cirobu.g00004275
Gene Model ID
KH2012:KH.C2.1146
Location
KhC2:7111725..7118839
Transcript Models and Sequences
cima8111439
Plate: VES74_A04
cieg011a20
Plate: R1CiGC17c20
ciad093k12
Plate: R1CiGC37k03
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Kelch_1 | Pfam | Kelch repeat type 1 |
Prot_kinase_dom | Pfam | Protein kinase domain |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | SMART | Protein kinase domain |
Kelch-typ_b-propeller | SUPERFAMILY | Kelch-type beta propeller |
Kelch-typ_b-propeller | Gene3D | Kelch-type beta propeller |
Kelch_1 | SMART | Kelch repeat type 1 |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
GO Term | Annotation Origin | Type |
---|---|---|
Golgi membrane | Blast | cellular component |
nucleotide binding | Blast | molecular function |
transcription coactivator activity | Blast | molecular function |
protein kinase activity | Blast | molecular function |
protein serine/threonine kinase activity | Blast | molecular function |
ubiquitin-protein transferase activity | Blast | molecular function |
signal transducer activity | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
intracellular | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
microtubule organizing center | Blast | cellular component |
cytosol | Blast | cellular component |
plasma membrane | Blast | cellular component |
protein phosphorylation | InterProScan | biological process |
membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
cytoplasmic vesicle | Blast | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
identical protein binding | Blast | molecular function |
intracellular membrane-bounded organelle | Blast | cellular component |
macromolecular complex binding | Blast | molecular function |
membrane raft | Blast | cellular component |
transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
enzyme regulator activity | Blast | molecular function |
intracellular signal transduction | Blast | biological process |
receptor binding | Blast | molecular function |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
endosome | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
membrane part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
endomembrane system | Blast | cellular component |
plasma membrane part | Blast | cellular component |
intracellular part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
Golgi membrane | Hs | cellular component | 111 | 1.78e-25 |
nucleotide binding | Hs | molecular function | 120 | 3.22e-28 |
transcription coactivator activity | Hs | molecular function | 117 | 1.64e-27 |
protein kinase activity | Hs | molecular function | 120 | 3.22e-28 |
protein serine/threonine kinase activity | Hs | molecular function | 120 | 3.22e-28 |
NF-kappaB-inducing kinase activity | Hs | molecular function | 117 | 1.64e-27 |
ubiquitin-protein transferase activity | Hs | molecular function | 111 | 1.78e-25 |
signal transducer activity | Hs | molecular function | 120 | 3.22e-28 |
death receptor binding | Hs | molecular function | 120 | 3.22e-28 |
protein binding | Hs | molecular function | 120 | 3.22e-28 |
ATP binding | Hs | molecular function | 120 | 3.22e-28 |
intracellular | Hs | cellular component | 117 | 1.64e-27 |
cytoplasm | Hs | cellular component | 120 | 3.22e-28 |
mitochondrion | Hs | cellular component | 120 | 3.22e-28 |
microtubule organizing center | Hs | cellular component | 111 | 1.78e-25 |
cytosol | Hs | cellular component | 120 | 3.22e-28 |
plasma membrane | Hs | cellular component | 120 | 3.22e-28 |
endosome membrane | Hs | cellular component | 120 | 3.22e-28 |
membrane | Hs | cellular component | 120 | 3.22e-28 |
kinase activity | Hs | molecular function | 120 | 3.22e-28 |
transferase activity | Hs | molecular function | 120 | 3.22e-28 |
COPII vesicle coat | Hs | cellular component | 111 | 1.78e-25 |
COPII-coated ER to Golgi transport vesicle | Hs | cellular component | 111 | 1.78e-25 |
death-inducing signaling complex | Hs | cellular component | 120 | 3.22e-28 |
cytoplasmic vesicle | Hs | cellular component | 111 | 1.78e-25 |
Cul3-RING ubiquitin ligase complex | Hs | cellular component | 111 | 1.78e-25 |
ubiquitin protein ligase binding | Hs | molecular function | 120 | 3.22e-28 |
identical protein binding | Hs | molecular function | 120 | 3.22e-28 |
intracellular membrane-bounded organelle | Hs | cellular component | 111 | 1.78e-25 |
receptor complex | Hs | cellular component | 120 | 3.22e-28 |
macromolecular complex binding | Hs | molecular function | 120 | 3.22e-28 |
membrane raft | Hs | cellular component | 120 | 3.22e-28 |
death domain binding | Hs | molecular function | 120 | 3.22e-28 |
ripoptosome | Hs | cellular component | 120 | 3.22e-28 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 3.8E-45 |
protein binding | Gene3D | molecular function | 1.0E-58 |
ATP binding | Pfam | molecular function | 3.8E-45 |
protein phosphorylation | Pfam | biological process | 3.8E-45 |