Gene Card
Best human hits
DLC1; STARD13; STARD8
Unique Gene ID
Cirobu.g00004142
Gene Model ID
KH2012:KH.C2.1026
Location
KhC2:1968786..1976645
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000004038 |
cien99149
Plate: VES85_E20
cien128601
Plate: VES90_G09
ciad008e04
Plate: R1CiGC01d24
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
RhoGAP_dom | SMART | Rho GTPase-activating protein domain |
RhoGAP_dom | ProSiteProfiles | Rho GTPase-activating protein domain |
Rho_GTPase_activation_prot | Gene3D | Rho GTPase activation protein |
RhoGAP_dom | Pfam | Rho GTPase-activating protein domain |
START-like_dom_sf | Gene3D | START-like domain superfamily |
Rho_GTPase_activation_prot | SUPERFAMILY | Rho GTPase activation protein |
START_lipid-bd_dom | ProSiteProfiles | START domain |
START_lipid-bd_dom | SMART | START domain |
START_lipid-bd_dom | Pfam | START domain |
GO Term | Annotation Origin | Type |
---|---|---|
GTPase activator activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Orthology | cellular component |
cytosol | Orthology | cellular component |
focal adhesion | Orthology | cellular component |
apoptotic process | Orthology | biological process |
signal transduction | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
cell junction | Orthology | cellular component |
mitochondrial membrane | Orthology | cellular component |
positive regulation of GTPase activity | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
nervous system development | Orthology | biological process |
anatomical structure morphogenesis | Orthology | biological process |
heart development | Orthology | biological process |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
membrane raft | Orthology | cellular component |
plasma membrane region | Orthology | cellular component |
endopeptidase activity | Orthology | molecular function |
positive regulation of hydrolase activity | Orthology | biological process |
positive regulation of apoptotic process | Orthology | biological process |
binding | Orthology | molecular function |
cell morphogenesis | Orthology | biological process |
organelle organization | Orthology | biological process |
cell migration | Orthology | biological process |
cell periphery | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
cytoskeletal part | Orthology | cellular component |
brain development | Orthology | biological process |
cell projection membrane | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
small GTPase mediated signal transduction | Orthology | biological process |
regulation of signal transduction | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
protein dephosphorylation | Orthology | biological process |
cell adhesion | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
neural tube closure | Hs | biological process |
heart morphogenesis | Hs | biological process |
GTPase activator activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
cytoplasm | Hs | cellular component |
mitochondrion | Hs | cellular component |
lipid droplet | Hs | cellular component |
cytosol | Hs | cellular component |
caveola | Hs | cellular component |
focal adhesion | Hs | cellular component |
apoptotic process | Hs | biological process |
activation of cysteine-type endopeptidase activity involved in apoptotic process | Hs | biological process |
signal transduction | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
lipid binding | Hs | molecular function |
regulation of cell shape | Hs | biological process |
membrane | Hs | cellular component |
actin cytoskeleton organization | Hs | biological process |
cell junction | Hs | cellular component |
negative regulation of cell migration | Hs | biological process |
cortical actin cytoskeleton | Hs | cellular component |
forebrain development | Hs | biological process |
mitochondrial membrane | Hs | cellular component |
ruffle membrane | Hs | cellular component |
regulation of actin cytoskeleton organization | Hs | biological process |
regulation of Rho protein signal transduction | Hs | biological process |
negative regulation of Rho protein signal transduction | Hs | biological process |
positive regulation of protein dephosphorylation | Hs | biological process |
SH2 domain binding | Hs | molecular function |
endothelial cell migration | Hs | biological process |
positive regulation of GTPase activity | Hs | biological process |
focal adhesion assembly | Hs | biological process |
regulation of small GTPase mediated signal transduction | Hs | biological process |
negative regulation of stress fiber assembly | Hs | biological process |
negative regulation of focal adhesion assembly | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
GTPase activator activity | Hs | molecular function | 515 | 8.66e-159 |
protein binding | Hs | molecular function | 515 | 8.66e-159 |
nucleus | Hs | cellular component | 515 | 8.66e-159 |
cytoplasm | Hs | cellular component | 515 | 8.66e-159 |
mitochondrion | Hs | cellular component | 491 | 1.32e-153 |
lipid droplet | Hs | cellular component | 491 | 1.32e-153 |
cytosol | Hs | cellular component | 515 | 8.66e-159 |
caveola | Hs | cellular component | 515 | 8.66e-159 |
focal adhesion | Hs | cellular component | 515 | 8.66e-159 |
lipid binding | Hs | molecular function | 515 | 8.66e-159 |
membrane | Hs | cellular component | 515 | 8.66e-159 |
cell junction | Hs | cellular component | 515 | 8.66e-159 |
cortical actin cytoskeleton | Hs | cellular component | 515 | 8.66e-159 |
mitochondrial membrane | Hs | cellular component | 491 | 1.32e-153 |
ruffle membrane | Hs | cellular component | 515 | 8.66e-159 |
SH2 domain binding | Hs | molecular function | 515 | 8.66e-159 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
signal transduction | Gene3D | biological process | 7.9E-69 |
lipid binding | Pfam | molecular function | 1.2E-23 |