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GENE CARD

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Gene Card

Best human hits

BPI; BPIFC; LBP

Unique Gene ID

Cirobu.g00003825

Gene Model ID

KH2012:KH.C14.395

Location

KhC14:1529730..1537253

Collections

Gateway full ORF

1 result

cima872795

Plate: VES67_O01

Gene collection 1 (N. Satoh)

1 result

cilv004g17

Plate: R1CiGC25o11

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
Bactericidal_perm-incr_a/b_dom SUPERFAMILY Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Lipid-bd_serum_glycop_N SMART Lipid-binding serum glycoprotein, N-terminal
BPI/LBP/Plunc PANTHER BPI/LBP/Plunc family
Lipid-bd_serum_glycop_C SMART Lipid-binding serum glycoprotein, C-terminal
Lipid-bd_serum_glycop_N Pfam Lipid-binding serum glycoprotein, N-terminal
Lipid-bd_serum_glycop_C Pfam Lipid-binding serum glycoprotein, C-terminal
BPI PANTHER Bactericidal permeability-increasing protein

GOSlim

45 results

GO Term Annotation Origin Type
immune system process Orthology biological process
receptor binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
cytoplasm Orthology cellular component
integral component of plasma membrane Orthology cellular component
immune response Orthology biological process
cell surface Orthology cellular component
membrane Orthology cellular component
cytokine-mediated signaling pathway Orthology biological process
response to lipopolysaccharide Orthology biological process
innate immune response Orthology biological process
extracellular exosome Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
vesicle Orthology cellular component
carbohydrate derivative binding Orthology molecular function
signal transduction Orthology biological process
cellular process Orthology biological process
anion binding Orthology molecular function
organic substance transport Orthology biological process
defense response Orthology biological process
binding Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
cytoplasmic vesicle Orthology cellular component
lysosome Orthology cellular component
vacuolar part Orthology cellular component
endomembrane system Orthology cellular component
intracellular organelle lumen Orthology cellular component
intracellular organelle part Orthology cellular component
response to bacterium Orthology biological process
cell migration Orthology biological process
chemotaxis Orthology biological process
ion transport Orthology biological process
organic substance metabolic process Orthology biological process
cellular metabolic process Orthology biological process
small molecule binding Orthology molecular function
organic cyclic compound binding Orthology molecular function
reproductive process Orthology biological process
cell motility Orthology biological process
cation binding Orthology molecular function
macromolecular complex Orthology cellular component
cellular protein modification process Orthology biological process
phosphate-containing compound metabolic process Orthology biological process

GO (Orthology)

71 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
lipopolysaccharide binding Hs molecular function
toll-like receptor signaling pathway Hs biological process
macrophage activation involved in immune response Hs biological process
immune system process Hs biological process
receptor binding Hs molecular function
protein binding Hs molecular function
phospholipid binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
cytoplasm Hs cellular component
integral component of plasma membrane Hs cellular component
lipid transport Hs biological process
acute-phase response Hs biological process
immune response Hs biological process
cellular defense response Hs biological process
lipid binding Hs molecular function
cell surface Hs cellular component
membrane Hs cellular component
cytokine-mediated signaling pathway Hs biological process
lipopolysaccharide-mediated signaling pathway Hs biological process
response to lipopolysaccharide Hs biological process
positive regulation of chemokine production Hs biological process
toll-like receptor 4 signaling pathway Hs biological process
azurophil granule lumen Hs cellular component
specific granule lumen Hs cellular component
defense response to bacterium Hs biological process
negative regulation of macrophage activation Hs biological process
negative regulation of growth of symbiont in host Hs biological process
innate immune response Hs biological process
defense response to Gram-negative bacterium Hs biological process
defense response to Gram-positive bacterium Hs biological process
extracellular exosome Hs cellular component
lipoteichoic acid binding Hs molecular function
cellular response to lipopolysaccharide Hs biological process
lipopeptide binding Hs molecular function
positive regulation of neutrophil chemotaxis Hs biological process
lipid transporter activity Hs molecular function
phospholipid transporter activity Hs molecular function
endoplasmic reticulum lumen Hs cellular component
lipid metabolic process Hs biological process
triglyceride metabolic process Hs biological process
steroid metabolic process Hs biological process
cholesterol metabolic process Hs biological process
phosphatidylethanolamine binding Hs molecular function
phosphatidylcholine transporter activity Hs molecular function
regulation of cholesterol efflux Hs biological process
cholesterol binding Hs molecular function
phospholipid transport Hs biological process
cholesterol transporter activity Hs molecular function
triglyceride binding Hs molecular function
diacylglycerol binding Hs molecular function
cholesterol transport Hs biological process
flagellated sperm motility Hs biological process
phosphatidylcholine binding Hs molecular function
vesicle Hs cellular component
high-density lipoprotein particle Hs cellular component
very-low-density lipoprotein particle remodeling Hs biological process
ceramide transporter activity Hs molecular function
ceramide transport Hs biological process
cholesterol homeostasis Hs biological process
post-translational protein modification Hs biological process
reverse cholesterol transport Hs biological process
phosphatidylcholine metabolic process Hs biological process
lipid homeostasis Hs biological process
phospholipid homeostasis Hs biological process
phosphatidic acid binding Hs molecular function
triglyceride homeostasis Hs biological process
ceramide binding Hs molecular function
phosphatidylglycerol binding Hs molecular function
phosphatidylethanolamine transporter activity Hs molecular function
phosphatidic acid transporter activity Hs molecular function

GO (Blast)

16 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
lipopolysaccharide binding Hs molecular function 172 2.97e-48
receptor binding Hs molecular function 172 2.97e-48
protein binding Hs molecular function 172 2.97e-48
phospholipid binding Hs molecular function 127 1.25e-31
extracellular region Hs cellular component 172 2.97e-48
extracellular space Hs cellular component 172 2.97e-48
cytoplasm Hs cellular component 171 1.57e-47
integral component of plasma membrane Hs cellular component 171 1.57e-47
lipid binding Hs molecular function 172 2.97e-48
cell surface Hs cellular component 172 2.97e-48
membrane Hs cellular component 172 2.97e-48
azurophil granule lumen Hs cellular component 171 1.57e-47
specific granule lumen Hs cellular component 171 1.57e-47
extracellular exosome Hs cellular component 172 2.97e-48
lipoteichoic acid binding Hs molecular function 172 2.97e-48
lipopeptide binding Hs molecular function 172 2.97e-48

GO (InterProScan)

4 results

GO Term Analysis Type e-value
lipopolysaccharide binding PANTHER molecular function 1.1E-93
immune response PANTHER biological process 1.1E-93
lipid binding SUPERFAMILY molecular function 1.99E-50
defense response to Gram-negative bacterium PANTHER biological process 1.1E-93