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GENE CARD

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Gene Card

Best human hits

BTRC; FBXW11; FBXW7

Unique Gene ID

Cirobu.g00003649

Gene Model ID

KH2012:KH.C14.230

Location

KhC14:26314..41909

Collections

Gateway full ORF

2 results

cien110299

Plate: VES87_G15

cima89546

Plate: VES57_G17

Gene collection 1 (N. Satoh)

1 result

citb2m2

Plate: R1CiGC28h12

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

12 results

IPR Term Analysis Definition
WD40_repeat_CS ProSitePatterns WD40 repeat, conserved site
WD40/YVTN_repeat-like_dom_sf Gene3D WD40/YVTN repeat-like-containing domain superfamily
WD40_repeat ProSiteProfiles WD40 repeat
F-box_dom Pfam F-box domain
F-box-like_dom_sf SUPERFAMILY F-box-like domain superfamily
WD40_repeat_dom_sf SUPERFAMILY WD40-repeat-containing domain superfamily
WD40_repeat SMART WD40 repeat
F-box_dom ProSiteProfiles F-box domain
G-protein_beta_WD-40_rep PRINTS G-protein beta WD-40 repeat
WD40_repeat Pfam WD40 repeat
F-box_dom SMART F-box domain
WD40_repeat_dom ProSiteProfiles WD40-repeat-containing domain

GOSlim

34 results

GO Term Annotation Origin Type
protein polyubiquitination Orthology biological process
vasculature development Orthology biological process
ubiquitin-protein transferase activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
nucleolus Orthology cellular component
cytoplasm Orthology cellular component
centrosome Blast cellular component
cytosol Orthology cellular component
protein ubiquitination Orthology biological process
ligase activity Blast molecular function
ubiquitin protein ligase binding Orthology molecular function
identical protein binding Orthology molecular function
protein dimerization activity Blast molecular function
organelle organization Orthology biological process
intracellular part Orthology cellular component
macromolecular complex Orthology cellular component
proteolysis Orthology biological process
DNA replication Orthology biological process
protein localization Orthology biological process
cellular protein modification process Orthology biological process
cell surface receptor signaling pathway Orthology biological process
positive regulation of catalytic activity Orthology biological process
transmembrane signaling receptor activity Orthology molecular function
protein kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
negative regulation of signal transduction Orthology biological process
Notch signaling pathway Orthology biological process
intracellular signal transduction Orthology biological process
protein phosphorylation Orthology biological process
enzyme regulator activity Orthology molecular function
cell cycle G1/S phase transition Orthology biological process
regulation of cellular metabolic process Orthology biological process

GO (Orthology)

36 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein polyubiquitination Hs biological process
vasculature development Hs biological process
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
nucleolus Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
sister chromatid cohesion Hs biological process
regulation of lipid storage Hs biological process
viral process Hs biological process
protein ubiquitination Hs biological process
SCF ubiquitin ligase complex Hs cellular component
cyclin binding Hs molecular function
protein binding, bridging Hs molecular function
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Hs biological process
positive regulation of protein ubiquitination Hs biological process
ubiquitin protein ligase binding Hs molecular function
negative regulation of DNA endoreduplication Hs biological process
regulation of protein localization Hs biological process
identical protein binding Hs molecular function
post-translational protein modification Hs biological process
positive regulation of epidermal growth factor-activated receptor activity Hs biological process
negative regulation of Notch signaling pathway Hs biological process
phosphothreonine residue binding Hs molecular function
protein stabilization Hs biological process
positive regulation of ubiquitin-protein transferase activity Hs biological process
lipid homeostasis Hs biological process
positive regulation of ERK1 and ERK2 cascade Hs biological process
ubiquitin-protein transferase activator activity Hs molecular function
positive regulation of proteasomal protein catabolic process Hs biological process
regulation of cell cycle G1/S phase transition Hs biological process
regulation of autophagy of mitochondrion Hs biological process
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Hs biological process

GO (Blast)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
ubiquitin ligase complex Hs cellular component 234 1.41e-68
ubiquitin-protein transferase activity Hs molecular function 763 0.0
protein binding Hs molecular function 763 0.0
nucleus Hs cellular component 763 0.0
nucleoplasm Hs cellular component 763 0.0
nucleolus Hs cellular component 763 0.0
cytoplasm Hs cellular component 763 0.0
centrosome Hs cellular component 234 1.41e-68
cytosol Hs cellular component 763 0.0
beta-catenin binding Hs molecular function 234 5.22e-68
ligase activity Hs molecular function 234 5.22e-68
SCF ubiquitin ligase complex Hs cellular component 763 0.0
cyclin binding Hs molecular function 763 0.0
protein binding, bridging Hs molecular function 763 0.0
ubiquitin protein ligase binding Hs molecular function 763 0.0
identical protein binding Hs molecular function 763 0.0
protein phosphorylated amino acid binding Hs molecular function 234 5.22e-68
protein dimerization activity Hs molecular function 234 1.41e-68
phosphothreonine residue binding Hs molecular function 763 0.0
ubiquitin protein ligase activity Hs molecular function 234 1.41e-68
ubiquitin-protein transferase activator activity Hs molecular function 763 0.0
Parkin-FBXW7-Cul1 ubiquitin ligase complex Hs cellular component 763 0.0

GO (InterProScan)

1 result

GO Term Analysis Type e-value
protein binding Gene3D molecular function 4.7E-122