Gene Card
Best human hits
BTRC; FBXW11; FBXW7
Unique Gene ID
Cirobu.g00003649
Gene Model ID
KH2012:KH.C14.230
Location
KhC14:26314..41909
cien110299
Plate: VES87_G15
cima89546
Plate: VES57_G17
citb2m2
Plate: R1CiGC28h12
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
WD40_repeat_CS | ProSitePatterns | WD40 repeat, conserved site |
WD40/YVTN_repeat-like_dom_sf | Gene3D | WD40/YVTN repeat-like-containing domain superfamily |
WD40_repeat | ProSiteProfiles | WD40 repeat |
F-box_dom | Pfam | F-box domain |
F-box-like_dom_sf | SUPERFAMILY | F-box-like domain superfamily |
WD40_repeat_dom_sf | SUPERFAMILY | WD40-repeat-containing domain superfamily |
WD40_repeat | SMART | WD40 repeat |
F-box_dom | ProSiteProfiles | F-box domain |
G-protein_beta_WD-40_rep | PRINTS | G-protein beta WD-40 repeat |
WD40_repeat | Pfam | WD40 repeat |
F-box_dom | SMART | F-box domain |
WD40_repeat_dom | ProSiteProfiles | WD40-repeat-containing domain |
GO Term | Annotation Origin | Type |
---|---|---|
protein polyubiquitination | Orthology | biological process |
vasculature development | Orthology | biological process |
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
centrosome | Blast | cellular component |
cytosol | Orthology | cellular component |
protein ubiquitination | Orthology | biological process |
ligase activity | Blast | molecular function |
ubiquitin protein ligase binding | Orthology | molecular function |
identical protein binding | Orthology | molecular function |
protein dimerization activity | Blast | molecular function |
organelle organization | Orthology | biological process |
intracellular part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
proteolysis | Orthology | biological process |
DNA replication | Orthology | biological process |
protein localization | Orthology | biological process |
cellular protein modification process | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
positive regulation of catalytic activity | Orthology | biological process |
transmembrane signaling receptor activity | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
positive regulation of signal transduction | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
Notch signaling pathway | Orthology | biological process |
intracellular signal transduction | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
enzyme regulator activity | Orthology | molecular function |
cell cycle G1/S phase transition | Orthology | biological process |
regulation of cellular metabolic process | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
ubiquitin ligase complex | Hs | cellular component | 234 | 1.41e-68 |
ubiquitin-protein transferase activity | Hs | molecular function | 763 | 0.0 |
protein binding | Hs | molecular function | 763 | 0.0 |
nucleus | Hs | cellular component | 763 | 0.0 |
nucleoplasm | Hs | cellular component | 763 | 0.0 |
nucleolus | Hs | cellular component | 763 | 0.0 |
cytoplasm | Hs | cellular component | 763 | 0.0 |
centrosome | Hs | cellular component | 234 | 1.41e-68 |
cytosol | Hs | cellular component | 763 | 0.0 |
beta-catenin binding | Hs | molecular function | 234 | 5.22e-68 |
ligase activity | Hs | molecular function | 234 | 5.22e-68 |
SCF ubiquitin ligase complex | Hs | cellular component | 763 | 0.0 |
cyclin binding | Hs | molecular function | 763 | 0.0 |
protein binding, bridging | Hs | molecular function | 763 | 0.0 |
ubiquitin protein ligase binding | Hs | molecular function | 763 | 0.0 |
identical protein binding | Hs | molecular function | 763 | 0.0 |
protein phosphorylated amino acid binding | Hs | molecular function | 234 | 5.22e-68 |
protein dimerization activity | Hs | molecular function | 234 | 1.41e-68 |
phosphothreonine residue binding | Hs | molecular function | 763 | 0.0 |
ubiquitin protein ligase activity | Hs | molecular function | 234 | 1.41e-68 |
ubiquitin-protein transferase activator activity | Hs | molecular function | 763 | 0.0 |
Parkin-FBXW7-Cul1 ubiquitin ligase complex | Hs | cellular component | 763 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | Gene3D | molecular function | 4.7E-122 |