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GENE CARD

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  1. Gene 'Phfumi.CG.MTP2014.S1...' > 
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  3. Gene 'KH2012:KH.S1585.2' > 

Gene Card

Best human hits

AKR1C3; GCLM

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00003425

Gene Model ID

KH2012:KH.C13.25

Location

KhC13:1002405..1011580

Transcript Models and Sequences

  KH2012:KH.C13.25.v1.B.ND2-1
KH2012:KH.C13.25.v2.A.SL1-1
KH2012:KH.C13.25.v2.A.SL3-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000014616
NCBI Reference Sequence XM_002128788.4
Collections

Gateway full ORF

3 results

cien160763

Plate: VES95_O03

cien172398

Plate: VES96_P22

cien216113

Plate: VES103_I19

Gene collection 1 (N. Satoh)

2 results

ciad030e03

Plate: R1CiGC03n19

ciad078f14

Plate: R1CiGC07p17

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
NADP_OxRdtase_dom Pfam NADP-dependent oxidoreductase domain
NADP_OxRdtase_dom_sf Gene3D NADP-dependent oxidoreductase domain superfamily
NADP_OxRdtase_dom_sf SUPERFAMILY NADP-dependent oxidoreductase domain superfamily
Gclm PANTHER Glutamate--cysteine ligase regulatory subunit

GOSlim

28 results

GO Term Annotation Origin Type
intracellular Blast cellular component
nucleus Blast cellular component
cytoplasm Blast cellular component
cytosol Orthology cellular component
response to oxidative stress Orthology biological process
enzyme regulator activity Orthology molecular function
protein heterodimerization activity Orthology molecular function
oxidation-reduction process Blast biological process
extracellular exosome Blast cellular component
ligase activity Orthology molecular function
cellular metabolic process Orthology biological process
peptide metabolic process Orthology biological process
developmental process Orthology biological process
organelle organization Orthology biological process
apoptotic process Orthology biological process
response to stimulus Orthology biological process
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component
enzyme binding Orthology molecular function
positive regulation of catalytic activity Orthology biological process
negative regulation of apoptotic process Orthology biological process
mitochondrion Orthology cellular component
cell Orthology cellular component
cellular response to organic substance Orthology biological process
cell surface receptor signaling pathway Orthology biological process
negative regulation of signal transduction Orthology biological process
catalytic activity Blast molecular function
organic substance metabolic process Blast biological process

GO (Orthology)

22 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
glutamate-cysteine ligase activity Hs molecular function
cytosol Hs cellular component
cysteine metabolic process Hs biological process
glutamate metabolic process Hs biological process
glutathione metabolic process Hs biological process
glutathione biosynthetic process Hs biological process
response to oxidative stress Hs biological process
aging Hs biological process
response to nutrient Hs biological process
apoptotic mitochondrial changes Hs biological process
response to activity Hs biological process
glutamate-cysteine ligase complex Hs cellular component
enzyme regulator activity Hs molecular function
glutamate-cysteine ligase catalytic subunit binding Hs molecular function
positive regulation of glutamate-cysteine ligase activity Hs biological process
response to drug Hs biological process
negative regulation of neuron apoptotic process Hs biological process
protein heterodimerization activity Hs molecular function
regulation of blood vessel size Hs biological process
regulation of mitochondrial depolarization Hs biological process
cellular response to glucose stimulus Hs biological process
negative regulation of extrinsic apoptotic signaling pathway Hs biological process

GO (Blast)

32 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
retinal dehydrogenase activity Hs molecular function 52.8 6.68e-08
alditol:NADP+ 1-oxidoreductase activity Hs molecular function 52.8 6.68e-08
aldo-keto reductase (NADP) activity Hs molecular function 52.8 6.68e-08
glutamate-cysteine ligase activity Hs molecular function 186 1.23e-57
retinol dehydrogenase activity Hs molecular function 52.8 6.68e-08
intracellular Hs cellular component 52.8 6.68e-08
nucleus Hs cellular component 52.8 6.68e-08
cytoplasm Hs cellular component 52.8 6.68e-08
cytosol Hs cellular component 186 1.23e-57
oxidoreductase activity Hs molecular function 52.8 6.68e-08
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor Hs molecular function 52.8 6.68e-08
glutamate-cysteine ligase complex Hs cellular component 186 1.23e-57
phenanthrene 9,10-monooxygenase activity Hs molecular function 52.8 6.68e-08
enzyme regulator activity Hs molecular function 186 1.23e-57
glutamate-cysteine ligase catalytic subunit binding Hs molecular function 186 1.23e-57
dihydrotestosterone 17-beta-dehydrogenase activity Hs molecular function 52.8 6.68e-08
prostaglandin H2 endoperoxidase reductase activity Hs molecular function 52.8 6.68e-08
prostaglandin D2 11-ketoreductase activity Hs molecular function 52.8 6.68e-08
geranylgeranyl reductase activity Hs molecular function 52.8 6.68e-08
ketoreductase activity Hs molecular function 52.8 6.68e-08
protein heterodimerization activity Hs molecular function 186 1.23e-57
prostaglandin-F synthase activity Hs molecular function 52.8 6.68e-08
15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity Hs molecular function 52.8 6.68e-08
androsterone dehydrogenase activity Hs molecular function 52.8 6.68e-08
testosterone dehydrogenase (NAD+) activity Hs molecular function 52.8 6.68e-08
testosterone 17-beta-dehydrogenase (NADP+) activity Hs molecular function 52.8 6.68e-08
ketosteroid monooxygenase activity Hs molecular function 52.8 6.68e-08
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity Hs molecular function 52.8 6.68e-08
indanol dehydrogenase activity Hs molecular function 52.8 6.68e-08
delta4-3-oxosteroid 5beta-reductase activity Hs molecular function 52.8 6.68e-08
NADP-retinol dehydrogenase activity Hs molecular function 52.8 6.68e-08
extracellular exosome Hs cellular component 52.8 6.68e-08

GO (InterProScan)

2 results

GO Term Analysis Type e-value
glutathione biosynthetic process PANTHER biological process 1.3E-87
glutamate-cysteine ligase catalytic subunit binding PANTHER molecular function 1.3E-87

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