Gene Card
Best human hits
ACHE; BCHE; NLGN4X
Unique Gene ID
Cirobu.g00002752
Gene Model ID
KH2012:KH.C12.218
Location
KhC12:5013873..5022872
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000004635 |
NCBI Reference Sequence | NM_001128877.1 |
cima8114961
Plate: VES74_E10
citb041d06
Plate: R1CiGC33a01
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IPR Term | Analysis | Definition |
---|---|---|
AB_hydrolase | SUPERFAMILY | Alpha/Beta hydrolase fold |
AB_hydrolase | Gene3D | Alpha/Beta hydrolase fold |
AChE_tetra | Pfam | Acetylcholinesterase, tetramerisation domain |
Carboxylesterase_B_AS | ProSitePatterns | Carboxylesterase type B, active site |
CarbesteraseB | Pfam | Carboxylesterase, type B |
AChE_tetra | ProDom | Acetylcholinesterase, tetramerisation domain |
Carboxylesterase_B_CS | ProSitePatterns | Carboxylesterase type B, conserved site |
Cholinesterase | PRINTS | Cholinesterase |
GO Term | Annotation Origin | Type |
---|---|---|
catalytic activity | Blast | molecular function |
protein binding | Blast | molecular function |
extracellular region | Blast | cellular component |
extracellular space | Blast | cellular component |
nucleus | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
endoplasmic reticulum lumen | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
plasma membrane | Blast | cellular component |
integral component of plasma membrane | Blast | cellular component |
cell surface | Blast | cellular component |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
hydrolase activity | Blast | molecular function |
serine hydrolase activity | Blast | molecular function |
enzyme binding | Blast | molecular function |
cell junction | Blast | cellular component |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
synapse | Blast | cellular component |
postsynaptic membrane | Blast | cellular component |
perinuclear region of cytoplasm | Blast | cellular component |
cell adhesion molecule binding | Blast | molecular function |
binding | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
nuclear envelope | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
organelle | Blast | cellular component |
postsynapse | Blast | cellular component |
neuron part | Blast | cellular component |
intrinsic component of membrane | Blast | cellular component |
anion binding | Blast | molecular function |
cation binding | Blast | molecular function |
receptor binding | Blast | molecular function |
synapse part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
amyloid-beta binding | Hs | molecular function | 442 | 1.20e-148 |
catalytic activity | Hs | molecular function | 442 | 1.20e-148 |
acetylcholinesterase activity | Hs | molecular function | 442 | 1.20e-148 |
cholinesterase activity | Hs | molecular function | 442 | 1.20e-148 |
receptor activity | Hs | molecular function | 263 | 7.49e-78 |
protein binding | Hs | molecular function | 404 | 1.46e-133 |
collagen binding | Hs | molecular function | 404 | 1.46e-133 |
extracellular region | Hs | cellular component | 442 | 1.20e-148 |
basal lamina | Hs | cellular component | 404 | 1.46e-133 |
extracellular space | Hs | cellular component | 442 | 1.20e-148 |
nucleus | Hs | cellular component | 404 | 1.46e-133 |
nuclear envelope lumen | Hs | cellular component | 442 | 1.20e-148 |
endoplasmic reticulum | Hs | cellular component | 442 | 1.20e-148 |
endoplasmic reticulum lumen | Hs | cellular component | 442 | 1.20e-148 |
Golgi apparatus | Hs | cellular component | 404 | 1.46e-133 |
plasma membrane | Hs | cellular component | 404 | 1.46e-133 |
integral component of plasma membrane | Hs | cellular component | 263 | 7.49e-78 |
cell surface | Hs | cellular component | 404 | 1.46e-133 |
postsynaptic density | Hs | cellular component | 263 | 7.49e-78 |
membrane | Hs | cellular component | 442 | 1.20e-148 |
integral component of membrane | Hs | cellular component | 404 | 1.46e-133 |
hydrolase activity | Hs | molecular function | 442 | 1.20e-148 |
hydrolase activity, acting on ester bonds | Hs | molecular function | 442 | 1.20e-148 |
serine hydrolase activity | Hs | molecular function | 404 | 1.46e-133 |
enzyme binding | Hs | molecular function | 442 | 1.20e-148 |
cell junction | Hs | cellular component | 404 | 1.46e-133 |
dendrite | Hs | cellular component | 263 | 7.49e-78 |
anchored component of membrane | Hs | cellular component | 404 | 1.46e-133 |
chloride ion binding | Hs | molecular function | 263 | 7.49e-78 |
neuromuscular junction | Hs | cellular component | 404 | 1.46e-133 |
choline binding | Hs | molecular function | 442 | 1.20e-148 |
neurexin family protein binding | Hs | molecular function | 263 | 7.49e-78 |
acetylcholine binding | Hs | molecular function | 404 | 1.46e-133 |
identical protein binding | Hs | molecular function | 442 | 1.20e-148 |
protein homodimerization activity | Hs | molecular function | 404 | 1.46e-133 |
synaptic cleft | Hs | cellular component | 404 | 1.46e-133 |
laminin binding | Hs | molecular function | 404 | 1.46e-133 |
protein self-association | Hs | molecular function | 404 | 1.46e-133 |
synapse | Hs | cellular component | 404 | 1.46e-133 |
postsynaptic membrane | Hs | cellular component | 263 | 7.49e-78 |
perinuclear region of cytoplasm | Hs | cellular component | 404 | 1.46e-133 |
cell adhesion molecule binding | Hs | molecular function | 263 | 7.49e-78 |
carboxylic ester hydrolase activity | Hs | molecular function | 442 | 1.20e-148 |
excitatory synapse | Hs | cellular component | 263 | 7.49e-78 |
blood microparticle | Hs | cellular component | 442 | 1.20e-148 |
spanning component of membrane | Hs | cellular component | 263 | 7.49e-78 |
scaffold protein binding | Hs | molecular function | 263 | 7.49e-78 |
symmetric, GABA-ergic, inhibitory synapse | Hs | cellular component | 263 | 7.49e-78 |
asymmetric, glutamatergic, excitatory synapse | Hs | cellular component | 263 | 7.49e-78 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
cholinesterase activity | PRINTS | molecular function | 5.8E-30 |