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GENE CARD

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Gene Card

Best human hits

EHMT2; KMT2A; KMT5A

Species

C. robusta formely Ciona int. type A

Unique Gene ID

Cirobu.g00002720

Gene Model ID

KH2012:KH.C12.19

Location

KhC12:4517168..4519584

Transcript Models and Sequences

  KH2012:KH.C12.19.v1.A.nonSL4-1
KH2012:KH.C12.19.v1.A.nonSL5-1
KH2012:KH.C12.19.v1.A.SL1-1
KH2012:KH.C12.19.v1.A.SL2-1
KH2012:KH.C12.19.v1.R.ND3-1

External Database Gene Card

External database links

2 results

Database Gene ID
ENSEMBL ENSCING00000014131
NCBI Reference Sequence XM_009862228.2
Collections

Gateway full ORF

2 results

cien48335

Plate: VES77_I21

cima858615

Plate: VES64_J08

Gene collection 1 (N. Satoh)

1 result

cieg003b11

Plate: R1CiGC15f10

WashU Genome Browser

Click here to view results in the tunicate WashU Browser

Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

4 results

IPR Term Analysis Definition
Hist_H4-K20_MeTrfase ProSiteProfiles Class V SAM-dependent methyltransferases
SET_dom Pfam SET domain
SET_dom SMART SET domain
SET_dom ProSiteProfiles SET domain

GOSlim

33 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II transcription factor activity, sequence-specific DNA binding Blast molecular function
DNA binding Blast molecular function
chromatin binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Blast molecular function
transcription corepressor activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytosol Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
cell cycle Orthology biological process
zinc ion binding Blast molecular function
transferase activity Orthology molecular function
identical protein binding Blast molecular function
protein homodimerization activity Blast molecular function
transcription regulatory region DNA binding Blast molecular function
negative regulation of transcription, DNA-templated Orthology biological process
metal ion binding Blast molecular function
cell division Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
organelle organization Orthology biological process
metabolic process Orthology biological process
cellular protein modification process Orthology biological process
intracellular signal transduction Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
regulation of signal transduction Orthology biological process
transcription regulatory region sequence-specific DNA binding Blast molecular function
sequence-specific double-stranded DNA binding Blast molecular function
nucleoplasm part Blast cellular component
macromolecular complex Blast cellular component
sequence-specific DNA binding Blast molecular function

GO (Orthology)

25 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
p53 binding Hs molecular function
transcription corepressor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
chromosome Hs cellular component
cytosol Hs cellular component
chromatin organization Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
cell cycle Hs biological process
methyltransferase activity Hs molecular function
lysine N-methyltransferase activity Hs molecular function
protein-lysine N-methyltransferase activity Hs molecular function
transferase activity Hs molecular function
histone-lysine N-methyltransferase activity Hs molecular function
peptidyl-lysine monomethylation Hs biological process
methylation Hs biological process
histone H4-K20 methylation Hs biological process
histone lysine methylation Hs biological process
histone methyltransferase activity (H4-K20 specific) Hs molecular function
regulation of DNA damage response, signal transduction by p53 class mediator Hs biological process
negative regulation of transcription, DNA-templated Hs biological process
cell division Hs biological process

GO (Blast)

29 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 79.0 6.02e-16
core promoter sequence-specific DNA binding Hs molecular function 79.0 6.02e-16
p53 binding Hs molecular function 191 3.91e-58
DNA binding Hs molecular function 79.0 6.02e-16
AT DNA binding Hs molecular function 79.0 6.02e-16
chromatin binding Hs molecular function 79.0 6.02e-16
transcription factor activity, sequence-specific DNA binding Hs molecular function 79.0 6.02e-16
transcription corepressor activity Hs molecular function 191 3.91e-58
protein binding Hs molecular function 191 3.91e-58
nucleus Hs cellular component 191 3.91e-58
nucleoplasm Hs cellular component 191 3.91e-58
chromosome Hs cellular component 191 3.91e-58
cytosol Hs cellular component 191 3.91e-58
methyltransferase activity Hs molecular function 191 3.91e-58
zinc ion binding Hs molecular function 79.0 6.02e-16
lysine N-methyltransferase activity Hs molecular function 191 3.91e-58
protein-lysine N-methyltransferase activity Hs molecular function 191 3.91e-58
transferase activity Hs molecular function 191 3.91e-58
histone-lysine N-methyltransferase activity Hs molecular function 191 3.91e-58
histone methyltransferase complex Hs cellular component 79.0 6.02e-16
histone methyltransferase activity (H4-K20 specific) Hs molecular function 191 3.91e-58
histone methyltransferase activity (H3-K4 specific) Hs molecular function 79.0 6.02e-16
identical protein binding Hs molecular function 79.0 6.02e-16
protein homodimerization activity Hs molecular function 79.0 6.02e-16
transcription regulatory region DNA binding Hs molecular function 79.0 6.02e-16
unmethylated CpG binding Hs molecular function 79.0 6.02e-16
metal ion binding Hs molecular function 79.0 6.02e-16
lysine-acetylated histone binding Hs molecular function 79.0 6.02e-16
MLL1 complex Hs cellular component 79.0 6.02e-16

GO (InterProScan)

2 results

GO Term Analysis Type e-value
protein binding SMART molecular function 7.4E-26
histone-lysine N-methyltransferase activity ProSiteProfiles molecular function 42.234

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