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GENE CARD

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Gene Card

Best human hits

SIAH1; SIAH2; SIAH3

Unique Gene ID

Cirobu.g00002555

Gene Model ID

KH2012:KH.C11.700

Location

KhC11:1362853..1367532

External Database Gene Card
Collections

Gateway full ORF

2 results

cien198392

Plate: VES101_O02

cien228680

Plate: VES105_A13

Gene collection 1 (N. Satoh)

1 result

cieg034a19

Plate: R1CiGC21e17

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

7 results

IPR Term Analysis Definition
SINA-like PANTHER E3 ubiquitin-protein ligase SIN-like
Znf_SIAH ProSiteProfiles Zinc finger, SIAH-type
Znf_RING/FYVE/PHD Gene3D Zinc finger, RING/FYVE/PHD-type
Znf_RING ProSiteProfiles Zinc finger, RING-type
TRAF-like Gene3D TRAF-like
7-in-absentia-prot_TRAF-dom Pfam Seven-in-absentia protein, TRAF-like domain
TRAF-like SUPERFAMILY TRAF-like

GOSlim

43 results

GO Term Annotation Origin Type
protein polyubiquitination Orthology biological process
transcription corepressor activity Orthology molecular function
ubiquitin-protein transferase activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
early endosome Orthology cellular component
cytosol Orthology cellular component
plasma membrane Orthology cellular component
apoptotic process Orthology biological process
cell cycle Orthology biological process
small GTPase mediated signal transduction Orthology biological process
multicellular organism development Orthology biological process
spermatogenesis Orthology biological process
nervous system development Orthology biological process
axon guidance Orthology biological process
protein C-terminus binding Orthology molecular function
zinc ion binding Orthology molecular function
anatomical structure morphogenesis Orthology biological process
protein ubiquitination Orthology biological process
transferase activity Orthology molecular function
cell differentiation Orthology biological process
identical protein binding Orthology molecular function
neuron projection Orthology cellular component
neuronal cell body Orthology cellular component
positive regulation of apoptotic process Orthology biological process
negative regulation of apoptotic process Orthology biological process
intracellular membrane-bounded organelle Orthology cellular component
metal ion binding Orthology molecular function
negative regulation of canonical Wnt signaling pathway Orthology biological process
negative regulation of nucleic acid-templated transcription Orthology biological process
proteolysis Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
protein metabolic process Orthology biological process
cytoplasmic part Orthology cellular component
macromolecular complex Orthology cellular component
regulation of cellular metabolic process Orthology biological process
enzyme binding Orthology molecular function
endopeptidase activity Orthology molecular function
cell surface receptor signaling pathway Orthology biological process
negative regulation of signal transduction Orthology biological process

GO (Orthology)

45 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
protein polyubiquitination Hs biological process
transcription corepressor activity Hs molecular function
ubiquitin-protein transferase activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
early endosome Hs cellular component
cytosol Hs cellular component
plasma membrane Hs cellular component
ubiquitin-dependent protein catabolic process Hs biological process
apoptotic process Hs biological process
cell cycle Hs biological process
small GTPase mediated signal transduction Hs biological process
multicellular organism development Hs biological process
spermatogenesis Hs biological process
nervous system development Hs biological process
axon guidance Hs biological process
protein C-terminus binding Hs molecular function
zinc ion binding Hs molecular function
anatomical structure morphogenesis Hs biological process
protein ubiquitination Hs biological process
protein deubiquitination Hs biological process
transferase activity Hs molecular function
cell differentiation Hs biological process
protein catabolic process Hs biological process
beta-catenin destruction complex Hs cellular component
regulation of protein ubiquitination Hs biological process
ubiquitin conjugating enzyme binding Hs molecular function
protein destabilization Hs biological process
identical protein binding Hs molecular function
neuron projection Hs cellular component
neuronal cell body Hs cellular component
positive regulation of apoptotic process Hs biological process
negative regulation of apoptotic process Hs biological process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Hs biological process
proteasome-mediated ubiquitin-dependent protein catabolic process Hs biological process
intracellular membrane-bounded organelle Hs cellular component
cellular protein catabolic process Hs biological process
metal ion binding Hs molecular function
neuron apoptotic process Hs biological process
ubiquitin protein ligase activity Hs molecular function
negative regulation of canonical Wnt signaling pathway Hs biological process
negative regulation of nucleic acid-templated transcription Hs biological process
negative regulation of extrinsic apoptotic signaling pathway Hs biological process

GO (Blast)

21 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
transcription corepressor activity Hs molecular function 448 3.07e-160
ubiquitin-protein transferase activity Hs molecular function 472 6.90e-170
protein binding Hs molecular function 472 6.90e-170
nucleus Hs cellular component 472 6.90e-170
nucleoplasm Hs cellular component 448 3.07e-160
cytoplasm Hs cellular component 472 6.90e-170
mitochondrion Hs cellular component 186 5.10e-58
early endosome Hs cellular component 472 6.90e-170
cytosol Hs cellular component 472 6.90e-170
plasma membrane Hs cellular component 472 6.90e-170
protein C-terminus binding Hs molecular function 472 6.90e-170
zinc ion binding Hs molecular function 472 6.90e-170
transferase activity Hs molecular function 472 6.90e-170
beta-catenin destruction complex Hs cellular component 472 6.90e-170
ubiquitin conjugating enzyme binding Hs molecular function 448 3.07e-160
identical protein binding Hs molecular function 472 6.90e-170
neuron projection Hs cellular component 448 3.07e-160
neuronal cell body Hs cellular component 448 3.07e-160
intracellular membrane-bounded organelle Hs cellular component 448 3.07e-160
metal ion binding Hs molecular function 472 6.90e-170
ubiquitin protein ligase activity Hs molecular function 472 6.90e-170

GO (InterProScan)

5 results

GO Term Analysis Type e-value
protein binding Gene3D molecular function 3.3E-72
nucleus PANTHER cellular component 9.0E-164
ubiquitin-dependent protein catabolic process PANTHER biological process 9.0E-164
multicellular organism development PANTHER biological process 9.0E-164
zinc ion binding ProSiteProfiles molecular function 16.455