Gene Card
Best human hits
SIAH1; SIAH2; SIAH3
Unique Gene ID
Cirobu.g00002555
Gene Model ID
KH2012:KH.C11.700
Location
KhC11:1362853..1367532
Transcript Models and Sequences
cien198392
Plate: VES101_O02
cien228680
Plate: VES105_A13
cieg034a19
Plate: R1CiGC21e17
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
SINA-like | PANTHER | E3 ubiquitin-protein ligase SIN-like |
Znf_SIAH | ProSiteProfiles | Zinc finger, SIAH-type |
Znf_RING/FYVE/PHD | Gene3D | Zinc finger, RING/FYVE/PHD-type |
Znf_RING | ProSiteProfiles | Zinc finger, RING-type |
TRAF-like | Gene3D | TRAF-like |
7-in-absentia-prot_TRAF-dom | Pfam | Seven-in-absentia protein, TRAF-like domain |
TRAF-like | SUPERFAMILY | TRAF-like |
GO Term | Annotation Origin | Type |
---|---|---|
protein polyubiquitination | Orthology | biological process |
transcription corepressor activity | Orthology | molecular function |
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
early endosome | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
apoptotic process | Orthology | biological process |
cell cycle | Orthology | biological process |
small GTPase mediated signal transduction | Orthology | biological process |
multicellular organism development | Orthology | biological process |
spermatogenesis | Orthology | biological process |
nervous system development | Orthology | biological process |
axon guidance | Orthology | biological process |
protein C-terminus binding | Orthology | molecular function |
zinc ion binding | Orthology | molecular function |
anatomical structure morphogenesis | Orthology | biological process |
protein ubiquitination | Orthology | biological process |
transferase activity | Orthology | molecular function |
cell differentiation | Orthology | biological process |
identical protein binding | Orthology | molecular function |
neuron projection | Orthology | cellular component |
neuronal cell body | Orthology | cellular component |
positive regulation of apoptotic process | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
intracellular membrane-bounded organelle | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
negative regulation of canonical Wnt signaling pathway | Orthology | biological process |
negative regulation of nucleic acid-templated transcription | Orthology | biological process |
proteolysis | Orthology | biological process |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
protein metabolic process | Orthology | biological process |
cytoplasmic part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
regulation of cellular metabolic process | Orthology | biological process |
enzyme binding | Orthology | molecular function |
endopeptidase activity | Orthology | molecular function |
cell surface receptor signaling pathway | Orthology | biological process |
negative regulation of signal transduction | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
transcription corepressor activity | Hs | molecular function | 448 | 3.07e-160 |
ubiquitin-protein transferase activity | Hs | molecular function | 472 | 6.90e-170 |
protein binding | Hs | molecular function | 472 | 6.90e-170 |
nucleus | Hs | cellular component | 472 | 6.90e-170 |
nucleoplasm | Hs | cellular component | 448 | 3.07e-160 |
cytoplasm | Hs | cellular component | 472 | 6.90e-170 |
mitochondrion | Hs | cellular component | 186 | 5.10e-58 |
early endosome | Hs | cellular component | 472 | 6.90e-170 |
cytosol | Hs | cellular component | 472 | 6.90e-170 |
plasma membrane | Hs | cellular component | 472 | 6.90e-170 |
protein C-terminus binding | Hs | molecular function | 472 | 6.90e-170 |
zinc ion binding | Hs | molecular function | 472 | 6.90e-170 |
transferase activity | Hs | molecular function | 472 | 6.90e-170 |
beta-catenin destruction complex | Hs | cellular component | 472 | 6.90e-170 |
ubiquitin conjugating enzyme binding | Hs | molecular function | 448 | 3.07e-160 |
identical protein binding | Hs | molecular function | 472 | 6.90e-170 |
neuron projection | Hs | cellular component | 448 | 3.07e-160 |
neuronal cell body | Hs | cellular component | 448 | 3.07e-160 |
intracellular membrane-bounded organelle | Hs | cellular component | 448 | 3.07e-160 |
metal ion binding | Hs | molecular function | 472 | 6.90e-170 |
ubiquitin protein ligase activity | Hs | molecular function | 472 | 6.90e-170 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | Gene3D | molecular function | 3.3E-72 |
nucleus | PANTHER | cellular component | 9.0E-164 |
ubiquitin-dependent protein catabolic process | PANTHER | biological process | 9.0E-164 |
multicellular organism development | PANTHER | biological process | 9.0E-164 |
zinc ion binding | ProSiteProfiles | molecular function | 16.455 |