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GENE CARD

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Gene Card

Best human hits

NR1I2; NR1I3; VDR

Unique Gene ID

Cirobu.g00001883

Gene Model ID

KH2012:KH.C10.80

Location

KhC10:2044290..2052749

External Database Gene Card

External database links

2 results

Collections
WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

11 results

IPR Term Analysis Definition
Znf_hrmn_rcpt ProSitePatterns Zinc finger, nuclear hormone receptor-type
NHR_like_dom_sf SUPERFAMILY Nuclear hormone receptor-like domain superfamily
Znf_NHR/GATA Gene3D Zinc finger, NHR/GATA-type
ThyrH_rcpt PRINTS Thyroid hormone receptor
Znf_hrmn_rcpt SMART Zinc finger, nuclear hormone receptor-type
Znf_hrmn_rcpt ProSiteProfiles Zinc finger, nuclear hormone receptor-type
Nucl_hrmn_rcpt_lig-bd SMART Nuclear hormone receptor, ligand-binding domain
Nucl_hrmn_rcpt_lig-bd Pfam Nuclear hormone receptor, ligand-binding domain
Znf_hrmn_rcpt PRINTS Zinc finger, nuclear hormone receptor-type
Znf_hrmn_rcpt Pfam Zinc finger, nuclear hormone receptor-type
Nuclear_hrmn_rcpt PRINTS Nuclear hormone receptor

GOSlim

47 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
cell morphogenesis Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
DNA binding Orthology molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
transcription coactivator activity Orthology molecular function
protein binding Orthology molecular function
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
transcription initiation from RNA polymerase II promoter Orthology biological process
signal transduction Orthology biological process
multicellular organism development Orthology biological process
zinc ion binding Orthology molecular function
negative regulation of cell proliferation Orthology biological process
positive regulation of gene expression Orthology biological process
nuclear body Orthology cellular component
sequence-specific DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
system development Orthology biological process
response to lipid Orthology biological process
signaling receptor activity Orthology molecular function
cellular response to organic substance Orthology biological process
cellular metabolic process Orthology biological process
metal ion transport Orthology biological process
cellular process Orthology biological process
cell Orthology cellular component
binding Orthology molecular function
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
small molecule binding Orthology molecular function
anion binding Orthology molecular function
organic cyclic compound binding Orthology molecular function
macromolecular complex Orthology cellular component
receptor binding Orthology molecular function
transcription factor binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
nuclear part Orthology cellular component

GO (Orthology)

53 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
cell morphogenesis Hs biological process
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
skeletal system development Hs biological process
DNA binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
steroid hormone receptor activity Hs molecular function
transcription coactivator activity Hs molecular function
nuclear receptor activity Hs molecular function
androgen receptor activity Hs molecular function
thyroid hormone receptor activity Hs molecular function
protein binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
transcription initiation from RNA polymerase II promoter Hs biological process
xenobiotic metabolic process Hs biological process
calcium ion transport Hs biological process
cellular calcium ion homeostasis Hs biological process
signal transduction Hs biological process
multicellular organism development Hs biological process
drug binding Hs molecular function
steroid metabolic process Hs biological process
zinc ion binding Hs molecular function
negative regulation of cell proliferation Hs biological process
calcitriol receptor activity Hs molecular function
animal organ morphogenesis Hs biological process
positive regulation of gene expression Hs biological process
nuclear body Hs cellular component
androgen receptor signaling pathway Hs biological process
intracellular receptor signaling pathway Hs biological process
lithocholic acid receptor activity Hs molecular function
receptor complex Hs cellular component
steroid hormone mediated signaling pathway Hs biological process
sequence-specific DNA binding Hs molecular function
intermediate filament cytoskeleton Hs cellular component
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
retinoid X receptor binding Hs molecular function
intestinal absorption Hs biological process
vitamin D receptor signaling pathway Hs biological process
vitamin D response element binding Hs molecular function
RNA polymerase II transcription factor complex Hs cellular component
calcitriol binding Hs molecular function
lithocholic acid binding Hs molecular function

GO (Blast)

30 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 186 1.78e-54
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 224 4.05e-69
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 186 1.78e-54
DNA binding Hs molecular function 224 4.05e-69
transcription factor activity, sequence-specific DNA binding Hs molecular function 224 4.05e-69
steroid hormone receptor activity Hs molecular function 224 4.05e-69
transcription coactivator activity Hs molecular function 186 1.78e-54
nuclear receptor activity Hs molecular function 224 4.05e-69
androgen receptor activity Hs molecular function 171 4.43e-50
thyroid hormone receptor activity Hs molecular function 186 1.78e-54
protein binding Hs molecular function 224 4.05e-69
nucleus Hs cellular component 224 4.05e-69
nucleoplasm Hs cellular component 224 4.05e-69
cytoplasm Hs cellular component 224 4.05e-69
cytosol Hs cellular component 171 4.43e-50
cytoskeleton Hs cellular component 171 4.43e-50
drug binding Hs molecular function 186 1.78e-54
zinc ion binding Hs molecular function 224 4.05e-69
calcitriol receptor activity Hs molecular function 224 4.05e-69
nuclear body Hs cellular component 186 1.78e-54
lithocholic acid receptor activity Hs molecular function 224 4.05e-69
receptor complex Hs cellular component 224 4.05e-69
sequence-specific DNA binding Hs molecular function 224 4.05e-69
intermediate filament cytoskeleton Hs cellular component 186 1.78e-54
metal ion binding Hs molecular function 224 4.05e-69
retinoid X receptor binding Hs molecular function 224 4.05e-69
vitamin D response element binding Hs molecular function 224 4.05e-69
RNA polymerase II transcription factor complex Hs cellular component 224 4.05e-69
calcitriol binding Hs molecular function 224 4.05e-69
lithocholic acid binding Hs molecular function 224 4.05e-69

GO (InterProScan)

9 results

GO Term Analysis Type e-value
DNA binding PRINTS molecular function 4.8E-18
transcription factor activity, sequence-specific DNA binding SMART molecular function 2.6E-34
steroid hormone receptor activity PRINTS molecular function 4.8E-18
thyroid hormone receptor activity PRINTS molecular function 4.4E-16
nucleus SMART cellular component 2.6E-34
regulation of transcription, DNA-templated SMART biological process 2.6E-35
zinc ion binding SMART molecular function 2.6E-34
steroid hormone mediated signaling pathway SMART biological process 2.6E-35
sequence-specific DNA binding SMART molecular function 2.6E-34