Gene Card
Best human hits
MITF; TFE3; TFEB
Unique Gene ID
Cirobu.g00001302
Gene Model ID
KH2012:KH.C10.106
Location
KhC10:2739066..2757514
Transcript Models and Sequences
KH2012:KH.C10.106.v1.A.ND2-1
KH2012:KH.C10.106.v1.A.nonSL3-1
KH2012:KH.C10.106.v2.A.ND1-1
cien101948
Plate: VES86_P04
cien149186
Plate: VES93_J13
cieg057n13
Plate: R1CiGC24d12
cilv041b12
Plate: R1CiGC28k08
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
bHLH_dom | Pfam | Myc-type, basic helix-loop-helix (bHLH) domain |
MiT/TFE_N | Pfam | MiT/TFE transcription factors, N-terminal |
bHLH_dom | ProSiteProfiles | Myc-type, basic helix-loop-helix (bHLH) domain |
HLH_DNA-bd_sf | Gene3D | Helix-loop-helix DNA-binding domain superfamily |
HLH_DNA-bd_sf | SUPERFAMILY | Helix-loop-helix DNA-binding domain superfamily |
bHLH_dom | SMART | Myc-type, basic helix-loop-helix (bHLH) domain |
TFEB | PANTHER | Transcription factor EB |
bHLH_dom | CDD | Myc-type, basic helix-loop-helix (bHLH) domain |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 222 | 3.13e-65 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 222 | 3.13e-65 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | Hs | molecular function | 222 | 3.13e-65 |
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | Hs | molecular function | 205 | 2.73e-59 |
DNA binding | Hs | molecular function | 222 | 3.13e-65 |
chromatin binding | Hs | molecular function | 205 | 2.73e-59 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 222 | 3.13e-65 |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | Hs | molecular function | 205 | 2.73e-59 |
protein binding | Hs | molecular function | 222 | 3.13e-65 |
nucleus | Hs | cellular component | 222 | 3.13e-65 |
nucleoplasm | Hs | cellular component | 222 | 3.13e-65 |
cytoplasm | Hs | cellular component | 209 | 1.22e-60 |
cytosol | Hs | cellular component | 222 | 3.13e-65 |
macromolecular complex | Hs | cellular component | 205 | 2.73e-59 |
transcription regulatory region DNA binding | Hs | molecular function | 222 | 3.13e-65 |
protein dimerization activity | Hs | molecular function | 222 | 3.13e-65 |
E-box binding | Hs | molecular function | 205 | 2.73e-59 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
humoral immune response | PANTHER | biological process | 4.4E-128 |
positive regulation of transcription, DNA-templated | PANTHER | biological process | 4.4E-128 |
protein dimerization activity | PANTHER | molecular function | 4.4E-128 |