Gene Card
Best human hits
PIM1; PIM2; PIM3
Unique Gene ID
Cirobu.g00000363
Gene Model ID
KH2012:KH.C1.153
Location
KhC1:6167725..6184556
Transcript Models and Sequences
cima888433
Plate: VES70_K05
cima891706
Plate: VES70_D22
citb029c20
Plate: R1CiGC31m16
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | SMART | Protein kinase domain |
PIM1/2/3 | PIRSF | Serine/threonine-protein kinase pim-1/2/3 |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
GO Term | Annotation Origin | Type |
---|---|---|
G1/S transition of mitotic cell cycle | Orthology | biological process |
nucleotide binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
protein phosphorylation | Orthology | biological process |
apoptotic process | Orthology | biological process |
cell cycle | Orthology | biological process |
multicellular organism development | Orthology | biological process |
transcription factor binding | Orthology | molecular function |
cell proliferation | Orthology | biological process |
negative regulation of cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
transferase activity | Orthology | molecular function |
cytokine-mediated signaling pathway | Orthology | biological process |
negative regulation of apoptotic process | Orthology | biological process |
positive regulation of transcription, DNA-templated | Orthology | biological process |
protein autophosphorylation | Orthology | biological process |
metal ion binding | Orthology | molecular function |
male gamete generation | Orthology | biological process |
organelle organization | Orthology | biological process |
transition metal ion binding | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
regulation of molecular function | Orthology | biological process |
macromolecular complex binding | Orthology | molecular function |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
intracellular signal transduction | Orthology | biological process |
positive regulation of signal transduction | Orthology | biological process |
signal transduction | Orthology | biological process |
response to lipid | Orthology | biological process |
cellular response to organic substance | Orthology | biological process |
anatomical structure formation involved in morphogenesis | Orthology | biological process |
heart development | Orthology | biological process |
positive regulation of cell proliferation | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
G1/S transition of mitotic cell cycle | Hs | biological process |
nucleotide binding | Hs | molecular function |
protein kinase activity | Hs | molecular function |
protein serine/threonine kinase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
nucleolus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
plasma membrane | Hs | cellular component |
protein phosphorylation | Hs | biological process |
apoptotic process | Hs | biological process |
cell cycle | Hs | biological process |
male meiotic nuclear division | Hs | biological process |
multicellular organism development | Hs | biological process |
regulation of mitotic cell cycle | Hs | biological process |
transcription factor binding | Hs | molecular function |
cell proliferation | Hs | biological process |
negative regulation of cell proliferation | Hs | biological process |
apoptotic mitochondrial changes | Hs | biological process |
response to virus | Hs | biological process |
positive regulation of autophagy | Hs | biological process |
membrane | Hs | cellular component |
positive regulation of macroautophagy | Hs | biological process |
kinase activity | Hs | molecular function |
phosphorylation | Hs | biological process |
transferase activity | Hs | molecular function |
cytokine-mediated signaling pathway | Hs | biological process |
manganese ion binding | Hs | molecular function |
hyaluronan metabolic process | Hs | biological process |
negative regulation of protein binding | Hs | biological process |
ribosomal small subunit binding | Hs | molecular function |
negative regulation of apoptotic process | Hs | biological process |
positive regulation of I-kappaB kinase/NF-kappaB signaling | Hs | biological process |
negative regulation of sequence-specific DNA binding transcription factor activity | Hs | biological process |
positive regulation of transcription, DNA-templated | Hs | biological process |
protein autophosphorylation | Hs | biological process |
metal ion binding | Hs | molecular function |
protein stabilization | Hs | biological process |
vitamin D receptor signaling pathway | Hs | biological process |
positive regulation of cardioblast proliferation | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 377 | 1.02e-131 |
protein kinase activity | Hs | molecular function | 377 | 1.02e-131 |
protein serine/threonine kinase activity | Hs | molecular function | 377 | 1.02e-131 |
protein binding | Hs | molecular function | 377 | 1.02e-131 |
ATP binding | Hs | molecular function | 377 | 1.02e-131 |
nucleus | Hs | cellular component | 375 | 3.76e-131 |
nucleoplasm | Hs | cellular component | 375 | 3.76e-131 |
nucleolus | Hs | cellular component | 375 | 3.76e-131 |
cytoplasm | Hs | cellular component | 377 | 1.02e-131 |
cytosol | Hs | cellular component | 377 | 1.02e-131 |
plasma membrane | Hs | cellular component | 375 | 3.76e-131 |
transcription factor binding | Hs | molecular function | 375 | 3.76e-131 |
membrane | Hs | cellular component | 375 | 3.76e-131 |
kinase activity | Hs | molecular function | 377 | 1.02e-131 |
transferase activity | Hs | molecular function | 377 | 1.02e-131 |
manganese ion binding | Hs | molecular function | 375 | 3.76e-131 |
ribosomal small subunit binding | Hs | molecular function | 375 | 3.76e-131 |
metal ion binding | Hs | molecular function | 375 | 3.76e-131 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 2.4E-19 |
protein serine/threonine kinase activity | PIRSF | molecular function | 4.6E-129 |
ATP binding | Pfam | molecular function | 2.4E-19 |
protein phosphorylation | Pfam | biological process | 2.4E-19 |
negative regulation of apoptotic process | PIRSF | biological process | 4.6E-129 |