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GENE CARD

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Gene Card

Best human hits

RUVBL1; RUVBL2; YME1L1

Unique Gene ID

Cirobu.g00000305

Gene Model ID

KH2012:KH.C1.1275

Location

KhC1:1837141..1840628

External Database Gene Card

External database links

2 results

Collections

Gateway full ORF

2 results

cien132284

Plate: VES91_B01

cien216656

Plate: VES103_E23

Gene collection 1 (N. Satoh)

1 result

cits039i02

Plate: R1CiGC34p18

WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

5 results

IPR Term Analysis Definition
TIP49_C Pfam TIP49, C-terminal
RuvB-like PANTHER RuvB-like
AAA+_ATPase SMART AAA+ ATPase domain
P-loop_NTPase SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase
RUVBL1 PANTHER RuvB-like helicase 1

GOSlim

56 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
transcription coactivator activity Orthology molecular function
transcription corepressor activity Blast molecular function
metalloendopeptidase activity Blast molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
intracellular Blast cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Blast cellular component
mitochondrial inner membrane Blast cellular component
centrosome Blast cellular component
microtubule organizing center Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
DNA repair Orthology biological process
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
cellular response to DNA damage stimulus Orthology biological process
cell cycle Orthology biological process
spermatogenesis Orthology biological process
peptidase activity Blast molecular function
metallopeptidase activity Blast molecular function
membrane Orthology cellular component
integral component of membrane Blast cellular component
nuclear body Blast cellular component
hydrolase activity Orthology molecular function
identical protein binding Blast molecular function
protein homodimerization activity Blast molecular function
metal ion binding Blast molecular function
unfolded protein binding Blast molecular function
cell division Orthology biological process
extracellular exosome Orthology cellular component
positive regulation of canonical Wnt signaling pathway Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nucleoplasm part Orthology cellular component
macromolecular complex Orthology cellular component
macromolecular complex binding Orthology molecular function
transcription factor binding Orthology molecular function
organelle organization Orthology biological process
nucleoside-triphosphatase activity Orthology molecular function
DNA metabolic process Orthology biological process
nuclear lumen Orthology cellular component
peptidase activity, acting on L-amino acid peptides Orthology molecular function
protein localization to organelle Orthology biological process
DNA binding Orthology molecular function
anion binding Orthology molecular function
adenyl ribonucleotide binding Orthology molecular function
cellular protein modification process Orthology biological process
cell adhesion molecule binding Orthology molecular function
enzyme binding Orthology molecular function
regulation of cellular metabolic process Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Blast molecular function
chromatin binding Blast molecular function

GO (Orthology)

51 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
nucleotide binding Hs molecular function
box C/D snoRNP assembly Hs biological process
Swr1 complex Hs cellular component
TFIID-class transcription factor binding Hs molecular function
DNA helicase activity Hs molecular function
transcription coactivator activity Hs molecular function
ATP-dependent DNA helicase activity Hs molecular function
helicase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
nucleus Hs cellular component
nucleoplasm Hs cellular component
cytoplasm Hs cellular component
microtubule organizing center Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
DNA repair Hs biological process
DNA recombination Hs biological process
chromatin organization Hs biological process
chromatin remodeling Hs biological process
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
cellular response to DNA damage stimulus Hs biological process
cell cycle Hs biological process
spermatogenesis Hs biological process
membrane Hs cellular component
nuclear matrix Hs cellular component
protein deubiquitination Hs biological process
hydrolase activity Hs molecular function
ATPase activity Hs molecular function
TBP-class protein binding Hs molecular function
intracellular ribonucleoprotein complex Hs cellular component
Ino80 complex Hs cellular component
DNA duplex unwinding Hs biological process
CENP-A containing nucleosome assembly Hs biological process
NuA4 histone acetyltransferase complex Hs cellular component
regulation of growth Hs biological process
ATP-dependent 5'-3' DNA helicase activity Hs molecular function
ADP binding Hs molecular function
histone H4 acetylation Hs biological process
histone H2A acetylation Hs biological process
cadherin binding Hs molecular function
ATPase binding Hs molecular function
cell division Hs biological process
extracellular exosome Hs cellular component
MLL1 complex Hs cellular component
positive regulation of canonical Wnt signaling pathway Hs biological process
R2TP complex Hs cellular component
regulation of autophagy of mitochondrion Hs biological process
positive regulation of telomerase RNA localization to Cajal body Hs biological process

GO (Blast)

50 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
nucleotide binding Hs molecular function 791 0.0
Swr1 complex Hs cellular component 791 0.0
RNA polymerase II core promoter sequence-specific DNA binding Hs molecular function 386 3.77e-131
RNA polymerase II distal enhancer sequence-specific DNA binding Hs molecular function 386 3.77e-131
TFIID-class transcription factor binding Hs molecular function 791 0.0
DNA helicase activity Hs molecular function 791 0.0
transcription coactivator activity Hs molecular function 791 0.0
transcription corepressor activity Hs molecular function 386 3.77e-131
ATP-dependent DNA helicase activity Hs molecular function 791 0.0
ATP-dependent peptidase activity Hs molecular function 50.4 1.50e-06
metalloendopeptidase activity Hs molecular function 50.4 1.50e-06
helicase activity Hs molecular function 791 0.0
protein binding Hs molecular function 791 0.0
ATP binding Hs molecular function 791 0.0
intracellular Hs cellular component 386 3.77e-131
nucleus Hs cellular component 791 0.0
nucleoplasm Hs cellular component 791 0.0
nuclear euchromatin Hs cellular component 386 3.77e-131
cytoplasm Hs cellular component 791 0.0
mitochondrion Hs cellular component 50.4 1.50e-06
mitochondrial inner membrane Hs cellular component 50.4 1.50e-06
centrosome Hs cellular component 386 3.77e-131
microtubule organizing center Hs cellular component 791 0.0
cytosol Hs cellular component 791 0.0
cytoskeleton Hs cellular component 791 0.0
beta-catenin binding Hs molecular function 386 3.77e-131
peptidase activity Hs molecular function 50.4 1.50e-06
metallopeptidase activity Hs molecular function 50.4 1.50e-06
membrane Hs cellular component 791 0.0
integral component of membrane Hs cellular component 50.4 1.50e-06
nuclear matrix Hs cellular component 791 0.0
nuclear body Hs cellular component 50.4 1.50e-06
hydrolase activity Hs molecular function 791 0.0
ATPase activity Hs molecular function 791 0.0
TBP-class protein binding Hs molecular function 791 0.0
intracellular ribonucleoprotein complex Hs cellular component 791 0.0
Ino80 complex Hs cellular component 791 0.0
chromatin DNA binding Hs molecular function 386 3.77e-131
NuA4 histone acetyltransferase complex Hs cellular component 791 0.0
identical protein binding Hs molecular function 386 3.77e-131
protein homodimerization activity Hs molecular function 386 3.77e-131
ATP-dependent 5'-3' DNA helicase activity Hs molecular function 791 0.0
ADP binding Hs molecular function 791 0.0
cadherin binding Hs molecular function 791 0.0
metal ion binding Hs molecular function 50.4 1.50e-06
unfolded protein binding Hs molecular function 386 3.77e-131
ATPase binding Hs molecular function 791 0.0
extracellular exosome Hs cellular component 791 0.0
MLL1 complex Hs cellular component 791 0.0
R2TP complex Hs cellular component 791 0.0

GO (InterProScan)

6 results

GO Term Analysis Type e-value
DNA helicase activity Pfam molecular function 4.7E-191
ATP binding Pfam molecular function 4.7E-191
Ino80 complex PANTHER cellular component 2.8E-248
NuA4 histone acetyltransferase complex PANTHER cellular component 2.8E-248
ATP-dependent 5'-3' DNA helicase activity PANTHER molecular function 2.8E-248
R2TP complex PANTHER cellular component 2.8E-248