Gene Card
Best human hits
RUVBL1; RUVBL2; YME1L1
Unique Gene ID
Cirobu.g00000305
Gene Model ID
KH2012:KH.C1.1275
Location
KhC1:1837141..1840628
Transcript Models and Sequences
KH2012:KH.C1.1275.v1.A.nonSL1-1
KH2012:KH.C1.1275.v1.A.SL2-1
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000004824 |
NCBI Reference Sequence | XM_002128830.3 |
cien132284
Plate: VES91_B01
cien216656
Plate: VES103_E23
cits039i02
Plate: R1CiGC34p18
n/a
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IPR Term | Analysis | Definition |
---|---|---|
TIP49_C | Pfam | TIP49, C-terminal |
RuvB-like | PANTHER | RuvB-like |
AAA+_ATPase | SMART | AAA+ ATPase domain |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
RUVBL1 | PANTHER | RuvB-like helicase 1 |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
transcription coactivator activity | Orthology | molecular function |
transcription corepressor activity | Blast | molecular function |
metalloendopeptidase activity | Blast | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
intracellular | Blast | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
mitochondrion | Blast | cellular component |
mitochondrial inner membrane | Blast | cellular component |
centrosome | Blast | cellular component |
microtubule organizing center | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
DNA repair | Orthology | biological process |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
cell cycle | Orthology | biological process |
spermatogenesis | Orthology | biological process |
peptidase activity | Blast | molecular function |
metallopeptidase activity | Blast | molecular function |
membrane | Orthology | cellular component |
integral component of membrane | Blast | cellular component |
nuclear body | Blast | cellular component |
hydrolase activity | Orthology | molecular function |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
metal ion binding | Blast | molecular function |
unfolded protein binding | Blast | molecular function |
cell division | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
positive regulation of canonical Wnt signaling pathway | Orthology | biological process |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
nucleoplasm part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
macromolecular complex binding | Orthology | molecular function |
transcription factor binding | Orthology | molecular function |
organelle organization | Orthology | biological process |
nucleoside-triphosphatase activity | Orthology | molecular function |
DNA metabolic process | Orthology | biological process |
nuclear lumen | Orthology | cellular component |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
protein localization to organelle | Orthology | biological process |
DNA binding | Orthology | molecular function |
anion binding | Orthology | molecular function |
adenyl ribonucleotide binding | Orthology | molecular function |
cellular protein modification process | Orthology | biological process |
cell adhesion molecule binding | Orthology | molecular function |
enzyme binding | Orthology | molecular function |
regulation of cellular metabolic process | Orthology | biological process |
RNA polymerase II regulatory region sequence-specific DNA binding | Blast | molecular function |
chromatin binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
box C/D snoRNP assembly | Hs | biological process |
Swr1 complex | Hs | cellular component |
TFIID-class transcription factor binding | Hs | molecular function |
DNA helicase activity | Hs | molecular function |
transcription coactivator activity | Hs | molecular function |
ATP-dependent DNA helicase activity | Hs | molecular function |
helicase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
microtubule organizing center | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
DNA repair | Hs | biological process |
DNA recombination | Hs | biological process |
chromatin organization | Hs | biological process |
chromatin remodeling | Hs | biological process |
transcription, DNA-templated | Hs | biological process |
regulation of transcription, DNA-templated | Hs | biological process |
regulation of transcription from RNA polymerase II promoter | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
cell cycle | Hs | biological process |
spermatogenesis | Hs | biological process |
membrane | Hs | cellular component |
nuclear matrix | Hs | cellular component |
protein deubiquitination | Hs | biological process |
hydrolase activity | Hs | molecular function |
ATPase activity | Hs | molecular function |
TBP-class protein binding | Hs | molecular function |
intracellular ribonucleoprotein complex | Hs | cellular component |
Ino80 complex | Hs | cellular component |
DNA duplex unwinding | Hs | biological process |
CENP-A containing nucleosome assembly | Hs | biological process |
NuA4 histone acetyltransferase complex | Hs | cellular component |
regulation of growth | Hs | biological process |
ATP-dependent 5'-3' DNA helicase activity | Hs | molecular function |
ADP binding | Hs | molecular function |
histone H4 acetylation | Hs | biological process |
histone H2A acetylation | Hs | biological process |
cadherin binding | Hs | molecular function |
ATPase binding | Hs | molecular function |
cell division | Hs | biological process |
extracellular exosome | Hs | cellular component |
MLL1 complex | Hs | cellular component |
positive regulation of canonical Wnt signaling pathway | Hs | biological process |
R2TP complex | Hs | cellular component |
regulation of autophagy of mitochondrion | Hs | biological process |
positive regulation of telomerase RNA localization to Cajal body | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 791 | 0.0 |
Swr1 complex | Hs | cellular component | 791 | 0.0 |
RNA polymerase II core promoter sequence-specific DNA binding | Hs | molecular function | 386 | 3.77e-131 |
RNA polymerase II distal enhancer sequence-specific DNA binding | Hs | molecular function | 386 | 3.77e-131 |
TFIID-class transcription factor binding | Hs | molecular function | 791 | 0.0 |
DNA helicase activity | Hs | molecular function | 791 | 0.0 |
transcription coactivator activity | Hs | molecular function | 791 | 0.0 |
transcription corepressor activity | Hs | molecular function | 386 | 3.77e-131 |
ATP-dependent DNA helicase activity | Hs | molecular function | 791 | 0.0 |
ATP-dependent peptidase activity | Hs | molecular function | 50.4 | 1.50e-06 |
metalloendopeptidase activity | Hs | molecular function | 50.4 | 1.50e-06 |
helicase activity | Hs | molecular function | 791 | 0.0 |
protein binding | Hs | molecular function | 791 | 0.0 |
ATP binding | Hs | molecular function | 791 | 0.0 |
intracellular | Hs | cellular component | 386 | 3.77e-131 |
nucleus | Hs | cellular component | 791 | 0.0 |
nucleoplasm | Hs | cellular component | 791 | 0.0 |
nuclear euchromatin | Hs | cellular component | 386 | 3.77e-131 |
cytoplasm | Hs | cellular component | 791 | 0.0 |
mitochondrion | Hs | cellular component | 50.4 | 1.50e-06 |
mitochondrial inner membrane | Hs | cellular component | 50.4 | 1.50e-06 |
centrosome | Hs | cellular component | 386 | 3.77e-131 |
microtubule organizing center | Hs | cellular component | 791 | 0.0 |
cytosol | Hs | cellular component | 791 | 0.0 |
cytoskeleton | Hs | cellular component | 791 | 0.0 |
beta-catenin binding | Hs | molecular function | 386 | 3.77e-131 |
peptidase activity | Hs | molecular function | 50.4 | 1.50e-06 |
metallopeptidase activity | Hs | molecular function | 50.4 | 1.50e-06 |
membrane | Hs | cellular component | 791 | 0.0 |
integral component of membrane | Hs | cellular component | 50.4 | 1.50e-06 |
nuclear matrix | Hs | cellular component | 791 | 0.0 |
nuclear body | Hs | cellular component | 50.4 | 1.50e-06 |
hydrolase activity | Hs | molecular function | 791 | 0.0 |
ATPase activity | Hs | molecular function | 791 | 0.0 |
TBP-class protein binding | Hs | molecular function | 791 | 0.0 |
intracellular ribonucleoprotein complex | Hs | cellular component | 791 | 0.0 |
Ino80 complex | Hs | cellular component | 791 | 0.0 |
chromatin DNA binding | Hs | molecular function | 386 | 3.77e-131 |
NuA4 histone acetyltransferase complex | Hs | cellular component | 791 | 0.0 |
identical protein binding | Hs | molecular function | 386 | 3.77e-131 |
protein homodimerization activity | Hs | molecular function | 386 | 3.77e-131 |
ATP-dependent 5'-3' DNA helicase activity | Hs | molecular function | 791 | 0.0 |
ADP binding | Hs | molecular function | 791 | 0.0 |
cadherin binding | Hs | molecular function | 791 | 0.0 |
metal ion binding | Hs | molecular function | 50.4 | 1.50e-06 |
unfolded protein binding | Hs | molecular function | 386 | 3.77e-131 |
ATPase binding | Hs | molecular function | 791 | 0.0 |
extracellular exosome | Hs | cellular component | 791 | 0.0 |
MLL1 complex | Hs | cellular component | 791 | 0.0 |
R2TP complex | Hs | cellular component | 791 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA helicase activity | Pfam | molecular function | 4.7E-191 |
ATP binding | Pfam | molecular function | 4.7E-191 |
Ino80 complex | PANTHER | cellular component | 2.8E-248 |
NuA4 histone acetyltransferase complex | PANTHER | cellular component | 2.8E-248 |
ATP-dependent 5'-3' DNA helicase activity | PANTHER | molecular function | 2.8E-248 |
R2TP complex | PANTHER | cellular component | 2.8E-248 |