ID

CONS00000656

Name

pCi-Pitx -2735/-2540 Second Forkhead site mutated:CES2:LacZ

Min Promoter

Endogenous Promoter

Reporter

LacZ

Comment

Minimal enhancer upstream of Pitx gene from -2735 to -2540, called D1bcde in the paper. The Pax binding site is absent. The second Forkhead regulatory motif was mutated (AAAAAACACTA => CCAACCCACTA). The mutation (m4 in the paper) affects the expression in the neurohypophysis primordium, anterior epidermis, ventral anterior sensory vesicle, but in the mesenchyme it seems that expression is higher.

KH transcript model was taken as reference for the region s coordinates.
The sequence is based on the first codon on the KH transcript.