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CONSTRUCT

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  1. Construct 'CONS00000009'

Construct

ID

CONS00000009

Name

pOtx -1541/-1417 GATA1 mutated pBra::NLSLacZ

Min Promoter

pBra

Reporter

LacZ

Comment

This construct contain the cis regulatory region of Otx gene about 1541 bp to 1417 bp upstream the start codon that correspond to the a-element in which the five GATA DNA motifs between 1465 and 1535 are mutated (GATA go to TATT).Note that the three distal most mifs are not indicated in the a-element sequence as their functionality is not clear.

This construct is testing Regulatory Region

REG00000015: Otx -1541/-1417 GATA1 mutated

Reference(s)