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CIS-REGULATION

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  1. Region 'REG00001524'

Cis-regulatory Region

Name

Cirobu.REG.KH2012.C1.8393686-8394898|Mir-1

Short name

Mir-1 upstream enhancer (Davidson 2006)

Region ID

REG00001524

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

regulatory_region
(enhancer)

Author

Brad Davidson (2021-09-24)

Annotator

Marion Gueroult-Bellone (2021-09-24)

Curator

Marion Gueroult-Bellone (2021-09-24)

View position in WashU

Description

Hierarchy of Regulatory Regions

Regulated gene(s)

KH2012:KH.C1.44 (KH.C1.44)

Construct(s) made to test this region

CONS00001573: p.Cirobu.REG.KH2012.C1.8393686-8394898>LacZ

Show in situ data
Overview of functional TF binding sites in this region

8,393,6868,394,898

Motif Name Binding Factor(s) Sequence Position in Region Comment

Sequence

Aniseed Coordinates: [8,393,686 / 8,394,898] on scaffold KhC1

This 1.2kb region is located upstream of Mir-1 (KH.C1.44) coding sequence. Interestingly it is embedded in the coding region for the mindbomb gene as seen in vertebrates. This region is specificaly active in the tail muscle lineage (B. Davidson, unpublished).

Show sequence

Length: 1,213

GAAGTAGGTGAGACAGACTCGAAATAACTTTTCAGAGCACCACCTTCCCTCGCACTGTAC
CGAAACTAACGAACTAATTAAATACGAATTCTGCATACAACCTTACTTCGCATTCCTGAT
CAGTGAACAGGCTACTCCTGCTTATCCCATTGGGAACTACTGTCGGTTCCATTCTTTAAC
AGCTGCTAGCGCCCTGTTATAACTCCATATGCGCAGAAACTCAGCTGTTTTGCTTTAGAC
GAAGTATTTTACGATCTAGAGCGATTTCTAAAGTCAGGAATTTTCTTATCTCTGCACGCC
TGGAAAGAACCGCCCGTTTTCACCACACACACCAACCAGGCGATTTTTCTTAACCAGGAA
TTCTGCCTCACAATTCTTACGCCAGACTAATCTGCGGAATCTCTATCGTGGATTAAATGG
GCGCTGTGACGAAGAACATCGTCCATTTAGTGGTGCAGCCAACGAAACTTATTGCATAGG
GCAGTTTTCCGCCCTAGGCTAGTGACGCAGCAGTGTTTTTAAGCGTGAACCGCTCCGTAA
CTTAAAACACAACCTCAACTTTAACATTACCTTAATTTTTATTAGTTTGTTTCTAACCGT
AATCTATTATAACGCTGGACGTAGTTATACTGAAGACAGTACACTGCAAAGATAGAACCG
AGAATGATGTCTCTTGGAATACCACGACGGCTTATATAGCGCTCTGGTCAGCGGCTGCGT
TTTTCGCCGCTTCGTCCTTTAGCACCTTTAAGAACGTCGTCACTTAGCTGTATTCAACGT
TTGTGAGATTCAGCTGCTATTACGCAACTGCATTCCCCGCCCCCTCTGCGAGTGTTGCCG
CAGAGCTGGAAATTATTTCACGCCGAATTGTAACGACTGCGATAAAGTGTTAACTTGAAT
TTTGACTCCAAATAAGTGTTGACTGAAATTTTTCCTTAGGTTTTACATTGTGCTAACGGA
CCAGGTTATTTTCCCGACTGTTCCCTTTAAAAGCGTTGACTGTTCGATTTTCCACTGGGA
AATACCATATATTTTGTGTTGTCGATTTTACTGAGTAAAACTCGTTTTACATCTTGCCAT
AATACGGTCTGCACCACACGGTACCAGTCGTCCGTATCACCCATCACATTGAACAGTCAC
TATGCACGCCCGTCCAACTGGTTCCTGACTCATGCACCACGAACGCTGTTATTGTTTCTC
GGTAGTGGCATGC

Reference(s)

Davidson et al. (2006). FGF signaling delineates the cardiac progenitor field in the simple chordate, Ciona intestinalis. Genes Dev. 20(19):2728-38

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