- Region 'REG00001398'
Cis-regulatory Region
Name
Cirobu.REG.KH2012.S605:17609-17833|βγ-crystallin
Short name
n/a
Region ID
REG00001398
Status
Curated
Origin
natural region from C. robusta formely Ciona int. type A
Type of Activity
no_output
Author
Wei-Chung Chen (2018-05-25)
Annotator
Marion Gueroult-Bellone (2018-05-25)
Curator
Marion Gueroult-Bellone (2018-05-25)
This 225bp sequence, located in the intergenic region upstream of βγ-crystallin (S605.3), drives no reporter gene expression in palps or pigment cells. It contains 115bp upstream of the TSS and 110bp downstream. It contains 1 CREB and 1 Nkx/POU putative binding sites conserved with Ciona savigny. Compared to the -275bp/+110bp enhancer, it lacks 1 Sox, 1 Fox and 2 Cdx conserved binding site and is not able to drive gene expression in pigment cells nor palps.
Modification of Cirobu.REG.KH2012.S605:17549-17833|βγ-crystallin by deletion
- Cirobu.REG.KH2012.S605:16609-17833|βγ-crystallin REG00001389 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:16789-17833|βγ-crystallin REG00001202 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:16809-17833|βγ-crystallin REG00001390 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17009-17833|βγ-crystallin REG00001391 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17209-17833|βγ-crystallin REG00001392 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17409-17833|βγ-crystallin REG00001393 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17448-17833|βγ-crystallin REG00001394 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17471-17833|βγ-crystallin REG00001395 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17540-17833|βγ-crystallin REG00001396 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17448-17833_SoxMut|βγ-crystallin REG00001399 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17448-17833_Cdx1Mut|βγ-crystallin REG00001400 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17448-17833_FoxMut|βγ-crystallin REG00001402 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17448-17833_CREBmut|βγ-crystallin REG00001403 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17448-17833|βγ-crystallin REG00001394 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17409-17833|βγ-crystallin REG00001393 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17209-17833|βγ-crystallin REG00001392 [ regulatory_region (extended_promoter) ]
- Cirobu.REG.KH2012.S605:17009-17833|βγ-crystallin REG00001391 [ regulatory_region (extended_promoter) ]
17,60917,833
| Motif Name | Binding Factor(s) | Sequence | Position in Region | Comment | |
|---|---|---|---|---|---|
| 1 | bZIP | n/a | gtcataa | [17,617 / 17,624] | This CREB binding site is located on the cis-regulatory region of βγ-crystallin (S605.3). It is conserved with Ciona savigny. Mutation of this CREB binding site inhibits enhancer activity in pigment cells. |
| 2 | Homeobox | n/a | tgtta | [17,624 / 17,629] | This Nkx/POU binding site is located on the cis-regulatory region of βγ-crystallin (S605.3). It is conserved with Ciona savigny. |
Aniseed Coordinates: [17,609 / 17,833] on scaffold KhS605
This sequence was retrieved using ANISEED Blast tool, thanks to the information provided in Fig1H of Chen et al. 2014.
Show sequence
Length: 225
tatgttacgtcataatgttaattgttgaataaaaatgaagaaacaaagccatgaagaagg
cggtttgttataaaacattgttgaagggatggaattaattatgttgttaacgtttgaatt
attgatgtaacaaggacgacaagtgagcgcaaatcagatttcgtttactttccttctaac
cctcctaaccactgcttatttcgcattttgtacaatcgaagtttc
