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CIS-REGULATION

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  1. Region 'REG00001245'

Cis-regulatory Region

Name

Cirobu.REG.KH2012.C9:5648755-5649375|DDR1; DDR2; MUSK

Short name

DDR1/2_CRM24_621pb

Region ID

REG00001245

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

no_output

Author

Diana S. José-Edwards (2017-09-09)

Annotator

Marion Gueroult-Bellone (2017-09-09)

Curator

Marion Gueroult-Bellone (2018-05-09)

View position in WashU

Description

This 621pb region, located upstream of DDR1/DDR2/MUSK (KH.C9.371), has no enhancer activity in the notochord

Hierarchy of Regulatory Regions

Modification of Cirobu.REG.KH2012.C9:5648367-5649375|DDR1; DDR2; MUSK by deletion

Regulated gene(s)

KH2012:KH.C9.371 (DDR1; DDR2)

Construct(s) made to test this region

CONS00001248: p.Cirobu.REG.KH2012.C9:5648755-5649375>LacZ

Show in situ data
Overview of functional TF binding sites in this region

5,648,7555,649,375

Motif Name Binding Factor(s) Sequence Position in Region Comment

Sequence

Aniseed Coordinates: [5,648,755 / 5,649,375] on scaffold KhC9

This sequence was retrieved using ANISEED Blast tool, thanks to the information provided in FigS2.a of Jose-Edwards et al. 2015.

Show sequence

Length: 621

gtaatttgagttgtaagaaggtgaccgattcttgacacgttccggggccgggtcgtcttt
ttgccggggagcgtgctcaaattttacgatcattctcggagtagctgaacgacgtccgtg
aggtaattataaggcggggtcaattccacgaaaacgcactgctggagatacggtgttcag
agacgcattgttcaacgagggtttacgacaggcagttacagtaaattgctgctaataatt
cgttaaatagtgccaagtaattttagaagatcttcggaattaaaatgaaaattattttca
aatgattcgattgatttgatagtttgataacgctagaagttcgtcccaatatgacctttc
cacattacgatgtcggtccttcaaaagtatgttgtgttaacggcgagtgtactactttca
atcgagcaaatattagatacaaaaatgggtcagtacttcaaacttaaggtttcgcgattg
ctggcgctctctgtttgtgtagtagggaataaattataaccattggtgtttgtaaaccgg
tcaaatgttgtcttggttcaacaaaacctggacagtttgattggtgttaatttatgagca
acaaaatgcgctcccatgttt

Reference(s)

José-Edwards et al. (2015). Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord. PLoS Genet. 11(12):e1005730

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