Description

Hierarchy of Regulatory Regions

Modification of Ci-COE -1043/-480 by deletion

Regulated gene(s)

KH2012:KH.L24.10 (EBF1; EBF2; EBF3)

Construct(s) made to test this region

CONS00001171: pCES.Cirobu.REG.KH2012.L24:33828-34036:prCirobu.bpFoxAa>LacZ

Overview of functional TF binding sites in this region

33,82834,036

	Motif Name	Binding Factor(s)	Sequence	Position in Region	Comment

Sequence

Aniseed Coordinates: [33,828 / 34,036] on scaffold KhL24

This sequence is a non-coding element conserved between Ciona intestinalis and Ciona savignyi. Original comment : These Ciona conserved non-coding elements (ciCNEs) are associated with largely the same key regulatory genes as vertebrate CNEs.

Reference(s)

Doglio et al. (2013). Parallel evolution of chordate cis-regulatory code for development. PLoS Genet. 9(11):e1003904