Aniseed - Cis-regulation

Region 'REG00001184'

Cis-regulatory Region

Name

Cirobu.REG.KH2012.C10:3142238-3142526/Meis

Short name

Meis_ciCNE5

Region ID

REG00001184

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

inactive_region

Author

Laura Doglio (2017-03-15)

Annotator

Marion Gueroult-Bellone (2017-03-15)

Curator

Delphine Dauga (2017-06-01)

View position in WashU

Description

Hierarchy of Regulatory Regions

Modification of Ci-meis -5312/98 by deletion

Ci-meis -6460/-2176 REG00000516 [ regulatory_region (complex_region) ]
- Ci-meis -5312/98 REG00000517 [ regulatory_region (extended_promoter) ]
  - Cirobu.REG.KH2012.C10:3142238-3142526/Meis REG00001184 [ inactive_region ]

Regulated gene(s)

KH2012:KH.C10.174 (MEIS1; MEIS2; MEIS3)

Construct(s) made to test this region

CONS00001166: pCES.Cirobu.REG.KH2012.C10:3142238-3142526:prCirobu.bpFoxAa>LacZ

Show in situ data

Overview of functional TF binding sites in this region

3,142,2383,142,526

	Motif Name	Binding Factor(s)	Sequence	Position in Region	Comment

Sequence

Aniseed Coordinates: [3,142,238 / 3,142,526] on scaffold KhC10

This sequence is a non-coding element conserved between Ciona intestinalis and Ciona savignyi. Original comment : These Ciona conserved non-coding elements (ciCNEs) are associated with largely the same key regulatory genes as vertebrate CNEs.

Show sequence

Length: 289

GGAGGCGAGCAAATTCCACGAGCAAATAGAAAAACAGCCGAGTTTCATCGGGGTTTGTTT
TTGAGGCGAGCGAGGGCCAGCAAGCACGTTTTATCACGCTTGGCTAGAAAAGAAGAAGCC
GTCGTAGTATTGGGCACAGTGACGCATACTCTGGCCTGTGTCAGTGTGATTCGGACAGCA
GAGAAAAGGCTTATATGTAGCCTTCTAGTCTTGGCAACCTGCAGAGCAGTGAGATTAAAT
GTCGACCTGCGTGCTTTCGTTTCAGATCGTTGATAGGTGCCTAACTCAG

Reference(s)

Doglio et al. (2013). Parallel evolution of chordate cis-regulatory code for development. PLoS Genet. 9(11):e1003904