- Region 'REG00001115'
Cis-regulatory Region
Name
Cirobu.REG.KH2012.C8:2621713-2622953|Foxd.b
Short name
Foxd.b (-1241pb)
Region ID
REG00001115
Status
Curated
Origin
natural region from C. robusta formely Ciona int. type A
Type of Activity
regulatory_region
(extended_promoter)
Author
Izumi Oda-Ishii (2017-01-31)
Annotator
Marion Gueroult-Bellone (2017-09-03)
Curator
Marion Gueroult-Bellone (2018-03-13)
The 1241pb upstream sequence of Foxd.b drives reporter expression specifically in the anterior and posterior vegetal hemisphere. It contains at least seven Tcf7 binding sites recquired for its activity.
Modification of Cirobu.REG.KH2012.C8:2620481-2622953|Foxd.b by deletion
2,621,7132,622,953
| Motif Name | Binding Factor(s) | Sequence | Position in Region | Comment | |
|---|---|---|---|---|---|
| 1 | TCF/LEF | n/a | tttg | [2,621,731 / 2,621,735] | One of the 5 Tcf7 binding sites located on the sequence localized -1241/-1042pb upstream of the TSS of KH.C8.396 (Foxd.b). These TFBS seem to be very important for enhancer activity of this upstream region. |
| 2 | TCF/LEF | n/a | ttt | [2,621,780 / 2,621,783] | One of the 5 Tcf7 binding sites located on the sequence localized -1241/-1042pb upstream of the TSS of KH.C8.396 (Foxd.b). These TFBS seem to be very important for enhancer activity of this upstream region. |
| 3 | TCF/LEF | n/a | tttg | [2,621,796 / 2,621,800] | One of the 5 Tcf7 binding sites located on the sequence localized -1241/-1042pb upstream of the TSS of KH.C8.396 (Foxd.b). These TFBS seem to be very important for enhancer activity of this upstream region. |
| 4 | TCF/LEF | n/a | tttg | [2,621,851 / 2,621,855] | One of the 5 Tcf7 binding sites located on the sequence localized -1241/-1042pb upstream of the TSS of KH.C8.396 (Foxd.b). These TFBS seem to be very important for enhancer activity of this upstream region. |
| 5 | TCF/LEF | n/a | tttg | [2,621,883 / 2,621,887] | One of the 5 Tcf7 binding sites located on the sequence localized -1241/-1042pb upstream of the TSS of KH.C8.396 (Foxd.b). These TFBS seem to be very important for enhancer activity of this upstream region. |
Aniseed Coordinates: [2,621,713 / 2,622,953] on scaffold KhC8
Sequence retrieved via the tool BLAST of Aniseed, thanks to the supporting information of the article (S4 Fig.)
Show sequence
Length: 1,241
tttgtttactttttttactttgtttatgttaagtaaagtttaatttcattaaagatgtta
gttcgactttaatcgtagcttagtttgactgatgtcgcgagtgattaggcgataagaagg
cgagaaatatcatcgatgtttgttcccgatatttggcggcgtttgtggcgtttgaaagag
gcgagttcgagtcgcgagtctcgatcttttcatctttatctcggttgaattgatttgtcg
tgaataaattgggaagttgtgtcgattggaacatcagttgcaagaatgagttgaacagtt
ggtccaattcaaacgttacttgcagtaaaacttgtgtggacaagttataacttaatacga
ggtgtatataaagtcgttagaattttacgaatcagttgacaaatataaataaaggtacag
gtagttttgttgaacattgcgacagtctgactgtgttttcagtttcgctaaatttctcgt
acggtaaaattgtttactaaaaaataagggcgtacgtaaatcaattctgggttgggtagc
tttaagcattacaataacgtacatattgcctgtttacaaatatagcagttatatttaaat
atatactaagaataaaggtgcagctcattcaaatttaatcgctttaccgattctctcaat
taagaataggagaaaacgcgtatttagataacatttaacgggaaacgactacagtcctaa
tattggaactacagacgttcaataaactcgttagcttgacatttatttcaatactgtttg
tgttacgtcacgggtatttttgagtcattattttaacgattggtcggattatttgaaaac
ctttaccacagtgtgttgttagaaaatagacgccatttttaccagcggaaccagcatttt
gccaaattcaaatttaataatttttttcagttgttttcaacattttgggacacttctcaa
aaaagcgaaatgttttttatgaaactcagtttttaaaaacagcgaaaacacgcatatttt
tgaacgcaaccattaatcgattaagttggacgtttttcttgtaaatgataaattaattag
ccttcttcttttgcttagaaaacattgtaatataatcttttgaaaaatctgttgctgatc
aacggaattataaacgagatctaggattcgaagaaaaaagcggttgctgggagaattgaa
gaagtggatttgaataaattgtcgcgttttgcaaagtgctc
