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CIS-REGULATION

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  1. Region 'REG00001112'

Cis-regulatory Region

Name

Cirobu.REG.KH2012.S654:26922-27074|Tbx6.b

Short name

Tbx6.b (-147)

Region ID

REG00001112

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

inactive_region

Author

Izumi Oda-Ishii (2017-01-30)

Annotator

Marion Gueroult-Bellone (2017-09-03)

Curator

Delphine Dauga (2017-03-07)


Description

147b region located upstream Tbx6.b TSS. It lacks one Tcf7 binding site compared to the 189pb minimal enhancer and is not able to drive gene expression.

Overview of functional TF binding sites in this region

26,92227,074

Motif Name Binding Factor(s) Sequence Position in Region Comment
1 TCF/LEF n/a ctttg [26,980 / 26,985] One of the 2 Tcf7 binding sites located on the 189pb upstream enhancer of KH.S654.3 (Tbx6.b). When 1 or both of these TFBS are missing or mutated, the enhancer is inactive.

Sequence

Aniseed Coordinates: [26,922 / 27,074] on scaffold KhS654

Sequence retrieved via the tool BLAST of Aniseed, thanks to the supporting information of the article (S5 Fig.)

Show sequence

Length: 153


cggaatgaggtactgtgaaactaaacccgttttatagcgagactcgttttcgatgccact
ttga
tcttaacgagtcattaacaaggacaactgcttcctgataagcctccgaactctcct
gctgattcaagtctagcgcatgcagaacactcc