Aniseed - Cis-regulation

Region 'REG00000603'

Cis-regulatory Region

Name

Ci-MBP -262/123

Short name

n/a

Region ID

REG00000603

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

regulatory_region
(extended_promoter)

Author

Christopher D. Brown (2009-12-12)

Annotator

Clara Degos (2010-07-22)

Curator

Delphine Dauga (2010-02-26)

View position in WashU

Description

Transcription start site is based on the start of the first exon of the KH transcript model.

This region corresponds to construct 1177 in the paper. In this construction the MyoD site was absent.

Hierarchy of Regulatory Regions

Modification of Ci-MBP -270/123 by deletion

Ci-MBP -1360/123 REG00000513 [ regulatory_region (extended_promoter) ]
- Ci-MBP -270/123 REG00000602 [ regulatory_region (extended_promoter) ]
  - Ci-MBP -262/123 REG00000603 [ regulatory_region (extended_promoter) ]
    - Ci-MBP -247/123 REG00000604 [ regulatory_region (extended_promoter) ]
      - Ci-MBP -214/123 REG00000605 [ regulatory_region (extended_promoter) ]
    - Ci-MBP -262/123 CRE mutated REG00000608 [ regulatory_region (extended_promoter) ]
  - Ci-MBP -268/123 Tbx6/CRE mutated REG00000607 [ regulatory_region (extended_promoter) ]
- Ci-MBP -1360/123 MyoD/Tbx6/CRE mutated REG00000606 [ regulatory_region (extended_promoter) ]

Regulated gene(s)

KH2012:KH.C1.1247 (KH.C1.1247)

Construct(s) made to test this region

CONS00000573: pCi-MBP -262/123::LacZ

Show in situ data

Overview of functional TF binding sites in this region

2,084,0892,084,473

	Motif Name	Binding Factor(s)	Sequence	Position in Region	Comment
1	bZIP	n/a	TGACGTTT	[2,084,444 / 2,084,451]
2	T-Box	n/a	ATAGCACCTA	[2,084,459 / 2,084,468]

Sequence

Aniseed Coordinates: [2,084,089 / 2,084,473] on scaffold KhC1

Transcription start site is based on the start of the first exon of the KH transcript model.

Show sequence

Length: 385

GTCGCATAGCACCTAGATTCGATGACGTTTCGTTAATTGCAACACTCGCAGCACTCAGCC
TTTTTCTCTTGCGTAGCAATCAGCACAGGGCGCCTTGCTCTTATCAGTAAGAAGCCGCAT
TCTTTTCTGCCAGTCAAGTTTTGCACAGACGAAGCACAGACCAAGTGACTCAAGGGTGTG
CAAGCATCTGTTAAGTTGTTTATATTATGTTGAATGTACTTGATGTGCATTTAAAACGAC
TGTAGAAGCAGTAAGCAGCAGGTTTTGTTATTTTTTTTTACAGATTCCCCTAGAATCATA
AACCATTAAGTTTTGAGTCGTACAACTGATCTGTGTTTCTAAACATCAGCGGAATTTGTT
TCAAATATCAAGATGCCAGTGCCAG

Reference(s)

Brown et al. (2007). Functional architecture and evolution of transcriptional elements that drive gene coexpression. Science 317(5844):1557-60