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CIS-REGULATION

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  1. Region 'REG00000500'

Cis-regulatory Region

Name

Ci-tropomyosin 1 -186bp/130bp mutated -86

Short name

n/a

Region ID

REG00000500

Status

Not Curated

Origin

engineered region from C. robusta formely Ciona int. type A

Type of Activity

regulatory_region
(extended_promoter)

Author

Christopher D. Brown (2009-12-09)

Annotator

Clara Degos (2010-07-23)

Curator

Clara Degos (2009-12-10)

View position in WashU

Description

Transcription start site is based on the start of the first exon of the KH transcript model.
Construct 1123.
This construct is the same that 913 excepted that there is a mutation in the G, in -86 position.

Hierarchy of Regulatory Regions

Modification of Ci-tropomyosin 1 -186/130 by substitution

Regulated gene(s)

KH2012:KH.C3.814 (TPM1; TPM3; TPM4)

Construct(s) made to test this region

CONS00000471: pCi-tropomyosin 1 -186bp/130bp mutated -86::LacZ

Show in situ data
Overview of functional TF binding sites in this region

4,231,8664,232,181

Motif Name Binding Factor(s) Sequence Position in Region Comment
1 bHLH n/a CAGCTG [4,232,062 / 4,232,067]
2 T-Box n/a CATTACCACCTT [4,232,079 / 4,232,088]
3 bZIP n/a TGACGTCA [4,232,089 / 4,232,096]
4 bZIP n/a TGACGTCA [4,232,104 / 4,232,111]

Sequence

Aniseed Coordinates: [4,231,866 / 4,232,181] on scaffold KhC3

Transcription start site is based on the start of the first exon of the KH transcript model.

Show sequence

Length: 316


CAAAGAAAGAATCGAAAGAAGAAATGGCGACTGTTTTTAACAACTTTCCACACCCGCAGG
TAAATCTTAATGACGTCAGACCATGTGACGTCATTACCACCTTAGACCTGTCAACAGCTG
TCTGTCATCGAAACTTGACCTAAATCTGGAGGCTTATAAAAGGGGACGTGGGCACTCGGC
AATACATCAGTTGCATACTACCTTCACAGTAAGTTCTTATATCTTTTCTATTGTGTTTAA
AACCACAACCTCTAAAATGGAAGCTATCAAGAAGAAGATGACCATGTTGAAATTGGACAA
AGAGAATGCACTCGAC

Reference(s)

Brown et al. (2007). Functional architecture and evolution of transcriptional elements that drive gene coexpression. Science 317(5844):1557-60

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