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CIS-REGULATION

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  1. Transcript 'KH2012:KH.C5.235.v1....' > 
  2. Transcript 'Cisavi.CG.ENS81.R49....' > 
  3. Transcript 'Cisavi.CG.ENS81.R2.3...' > 
  4. Transcript 'Cisavi.CG.ENS81.R2.3...' > 
  5. Region 'REG00000087'

Cis-regulatory Region

Name

Ci-MLC2 -53/61

Short name

n/a

Region ID

REG00000087

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

regulatory_region
(RNApol_II_core_promoter)

Author

Kusakabe team (2007-01-28)

Annotator

Jonathan Luchino (2007-05-15)

Curator

Delphine Dauga (2010-04-08)

View position in WashU

Description

The M2 motifs present in the enhancer sequence upstream the +1 of transcription of the Ci-MLC2 gene are necessary and sufficient for the expression in the muscle cells.

Be careful, coordinates in the paper are different from ANISEED coordinates. We took the KH transcript model as reference.

Coordinates in the paper : -115bp/-1bp

Hierarchy of Regulatory Regions

Modification of Ci-MLC2 -438/205 by deletion

Regulated gene(s)

KH2012:KH.C1.20 (MYL1; MYL4; MYL6B)

Construct(s) made to test this region

CONS00000077: pMLC2 -53/61::GFP

Show in situ data
Overview of functional TF binding sites in this region

7,191,2667,191,379

Motif Name Binding Factor(s) Sequence Position in Region Comment

Sequence

Aniseed Coordinates: [7,191,266 / 7,191,379] on scaffold KhC1

This sequence was found with a blast on the JGI site with the sequence includes in the publication listed bellow.

Show sequence

Length: 114

TATCAGGTCATTATGTCTGTTATAAAAGCGCTGGGTCGAAGTTTAACAGCATTCAGTTCT
GCTTAAGCATAATCTAGCAAGCATCAAACATCCTTCAAGACGATAAACTATTAT

Reference(s)

Kusakabe et al. (2004). Computational discovery of DNA motifs associated with cell type-specific gene expression in Ciona. Dev. Biol. 276(2):563-80

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