Gene Card
Best human hits
AC011462.1; BCKDHA; PDHA1
Species
Unique Gene ID
Moocci.g00018819
Gene Model ID
Moocci.CG.ELv1_2.S497425.g18819
Location
S497425:5375..6991
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
3 results
| IPR Term | Analysis | Definition |
|---|---|---|
| BCKDH_E1-a | PANTHER | 2-oxoisovalerate dehydrogenase subunit alpha |
| DH_E1 | Pfam | Dehydrogenase, E1 component |
| THDP-binding | SUPERFAMILY | Thiamin diphosphate-binding fold |
| GO Term | Annotation Origin | Type |
|---|
GO (Orthology)
13 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| alpha-ketoacid dehydrogenase activity | Hs | molecular function |
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| mitochondrion | Hs | cellular component |
| mitochondrial matrix | Hs | cellular component |
| mitochondrial alpha-ketoglutarate dehydrogenase complex | Hs | cellular component |
| metabolic process | Hs | biological process |
| branched-chain amino acid catabolic process | Hs | biological process |
| oxidoreductase activity | Hs | molecular function |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function |
| carboxy-lyase activity | Hs | molecular function |
| metal ion binding | Hs | molecular function |
| oxidation-reduction process | Hs | biological process |
GO (Blast)
18 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| alpha-ketoacid dehydrogenase activity | Hs | molecular function | 481 | 4.87e-170 |
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | Hs | molecular function | 481 | 4.87e-170 |
| pyruvate dehydrogenase activity | Hs | molecular function | 118 | 3.82e-30 |
| pyruvate dehydrogenase (acetyl-transferring) activity | Hs | molecular function | 118 | 3.82e-30 |
| protein binding | Hs | molecular function | 466 | 1.15e-164 |
| nucleus | Hs | cellular component | 118 | 3.82e-30 |
| nucleolus | Hs | cellular component | 118 | 3.82e-30 |
| mitochondrion | Hs | cellular component | 466 | 1.15e-164 |
| mitochondrial matrix | Hs | cellular component | 466 | 1.15e-164 |
| mitochondrial alpha-ketoglutarate dehydrogenase complex | Hs | cellular component | 466 | 1.15e-164 |
| oxidoreductase activity | Hs | molecular function | 466 | 1.15e-164 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Hs | molecular function | 481 | 4.87e-170 |
| carboxy-lyase activity | Hs | molecular function | 466 | 1.15e-164 |
| pyruvate dehydrogenase (NAD+) activity | Hs | molecular function | 118 | 3.82e-30 |
| myelin sheath | Hs | cellular component | 118 | 3.82e-30 |
| intracellular membrane-bounded organelle | Hs | cellular component | 118 | 3.82e-30 |
| pyruvate dehydrogenase complex | Hs | cellular component | 118 | 3.82e-30 |
| metal ion binding | Hs | molecular function | 466 | 1.15e-164 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| alpha-ketoacid dehydrogenase activity | PANTHER | molecular function | 7.9E-173 |
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | PANTHER | molecular function | 7.9E-173 |
| metabolic process | Pfam | biological process | 1.4E-84 |
| branched-chain amino acid catabolic process | PANTHER | biological process | 7.9E-173 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | Pfam | molecular function | 1.4E-84 |
