Gene Card
Best human hits
TP53; TP63; TP73
Unique Gene ID
Cirobu.g00005915
Gene Model ID
KH2012:KH.C3.713
Location
KhC3:512892..514879
Transcript Models and Sequences
Database | Gene ID |
---|---|
ENSEMBL | ENSCING00000002175 |
cien104395
Plate: VES86_C15
cien154030
Plate: VES94_J04
cits031o11
Plate: R1CiGC34c17
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
p53_DNA-bd | CDD | p53, DNA-binding domain |
p53_tumour_suppressor | PRINTS | p53 tumour suppressor family |
p53_tetramer_sf | Gene3D | p53-like tetramerisation domain superfamily |
p53-like_TF_DNA-bd | SUPERFAMILY | p53-like transcription factor, DNA-binding |
p53_tetramer_sf | SUPERFAMILY | p53-like tetramerisation domain superfamily |
p53_tetrameristn | Pfam | p53, tetramerisation domain |
p53/RUNT-type_TF_DNA-bd_sf | Gene3D | p53/RUNT-type transcription factor, DNA-binding domain superfamily |
p53_DNA-bd | Pfam | p53, DNA-binding domain |
p53_tumour_suppressor | PANTHER | p53 tumour suppressor family |
GO Term | Annotation Origin | Type |
---|---|---|
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Blast | molecular function |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
transcription factor activity, transcription factor binding | Blast | molecular function |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | Blast | molecular function |
DNA binding | Blast | molecular function |
chromatin binding | Blast | molecular function |
double-stranded DNA binding | Blast | molecular function |
transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
intracellular | Blast | cellular component |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
mitochondrial matrix | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Blast | cellular component |
regulation of transcription, DNA-templated | InterProScan | biological process |
apoptotic process | InterProScan | biological process |
transcription factor binding | Blast | molecular function |
zinc ion binding | Blast | molecular function |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
nuclear body | Blast | cellular component |
enzyme binding | Blast | molecular function |
protein kinase binding | Blast | molecular function |
cell junction | Blast | cellular component |
ubiquitin protein ligase binding | Blast | molecular function |
macromolecular complex | Blast | cellular component |
identical protein binding | Blast | molecular function |
neuron projection | Blast | cellular component |
intracellular membrane-bounded organelle | Blast | cellular component |
sequence-specific DNA binding | Blast | molecular function |
transcription regulatory region DNA binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
protein heterodimerization activity | Blast | molecular function |
protein N-terminus binding | Blast | molecular function |
intracellular organelle part | Blast | cellular component |
intracellular non-membrane-bounded organelle | Blast | cellular component |
nuclear lumen | Blast | cellular component |
transcription regulatory region sequence-specific DNA binding | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
RNA binding | Blast | molecular function |
transition metal ion binding | Blast | molecular function |
intracellular part | Blast | cellular component |
nucleoplasm part | Blast | cellular component |
receptor binding | Blast | molecular function |
protein oligomerization | InterProScan | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
chromatin | Hs | cellular component | 199 | 9.93e-58 |
nuclear chromatin | Hs | cellular component | 194 | 1.24e-55 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 199 | 9.93e-58 |
RNA polymerase II transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 199 | 9.93e-58 |
transcription factor activity, transcription factor binding | Hs | molecular function | 194 | 1.24e-55 |
transcription factor activity, core RNA polymerase binding | Hs | molecular function | 166 | 3.82e-47 |
core promoter sequence-specific DNA binding | Hs | molecular function | 166 | 3.82e-47 |
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly | Hs | molecular function | 166 | 3.82e-47 |
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | Hs | molecular function | 199 | 9.93e-58 |
transcription factor activity, TFIID-class binding | Hs | molecular function | 166 | 3.82e-47 |
RNA polymerase II transcription factor binding | Hs | molecular function | 166 | 3.82e-47 |
TFIID-class transcription factor binding | Hs | molecular function | 166 | 3.82e-47 |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | Hs | molecular function | 166 | 3.82e-47 |
protease binding | Hs | molecular function | 166 | 3.82e-47 |
p53 binding | Hs | molecular function | 199 | 9.93e-58 |
DNA binding | Hs | molecular function | 199 | 9.93e-58 |
chromatin binding | Hs | molecular function | 199 | 9.93e-58 |
damaged DNA binding | Hs | molecular function | 199 | 9.93e-58 |
double-stranded DNA binding | Hs | molecular function | 194 | 1.24e-55 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 199 | 9.93e-58 |
mRNA 3'-UTR binding | Hs | molecular function | 166 | 3.82e-47 |
copper ion binding | Hs | molecular function | 166 | 3.82e-47 |
protein binding | Hs | molecular function | 199 | 9.93e-58 |
ATP binding | Hs | molecular function | 166 | 3.82e-47 |
intracellular | Hs | cellular component | 166 | 3.82e-47 |
nucleus | Hs | cellular component | 199 | 9.93e-58 |
nucleoplasm | Hs | cellular component | 199 | 9.93e-58 |
replication fork | Hs | cellular component | 166 | 3.82e-47 |
transcription factor complex | Hs | cellular component | 199 | 9.93e-58 |
transcription factor TFIID complex | Hs | cellular component | 166 | 3.82e-47 |
nucleolus | Hs | cellular component | 166 | 3.82e-47 |
cytoplasm | Hs | cellular component | 199 | 9.93e-58 |
mitochondrion | Hs | cellular component | 199 | 9.93e-58 |
mitochondrial matrix | Hs | cellular component | 166 | 3.82e-47 |
endoplasmic reticulum | Hs | cellular component | 166 | 3.82e-47 |
rough endoplasmic reticulum | Hs | cellular component | 194 | 1.24e-55 |
Golgi apparatus | Hs | cellular component | 199 | 9.93e-58 |
cytosol | Hs | cellular component | 199 | 9.93e-58 |
transcription factor binding | Hs | molecular function | 199 | 9.93e-58 |
zinc ion binding | Hs | molecular function | 166 | 3.82e-47 |
membrane | Hs | cellular component | 166 | 3.82e-47 |
integral component of membrane | Hs | cellular component | 166 | 3.82e-47 |
nuclear matrix | Hs | cellular component | 166 | 3.82e-47 |
nuclear body | Hs | cellular component | 166 | 3.82e-47 |
PML body | Hs | cellular component | 166 | 3.82e-47 |
enzyme binding | Hs | molecular function | 166 | 3.82e-47 |
protein kinase binding | Hs | molecular function | 199 | 9.93e-58 |
protein phosphatase binding | Hs | molecular function | 166 | 3.82e-47 |
protein domain specific binding | Hs | molecular function | 194 | 1.24e-55 |
cell junction | Hs | cellular component | 199 | 9.93e-58 |
dendrite | Hs | cellular component | 194 | 1.24e-55 |
receptor tyrosine kinase binding | Hs | molecular function | 166 | 3.82e-47 |
ubiquitin protein ligase binding | Hs | molecular function | 166 | 3.82e-47 |
macromolecular complex | Hs | cellular component | 166 | 3.82e-47 |
histone acetyltransferase binding | Hs | molecular function | 166 | 3.82e-47 |
identical protein binding | Hs | molecular function | 199 | 9.93e-58 |
histone deacetylase binding | Hs | molecular function | 166 | 3.82e-47 |
neuron projection | Hs | cellular component | 194 | 1.24e-55 |
intracellular membrane-bounded organelle | Hs | cellular component | 199 | 9.93e-58 |
sequence-specific DNA binding | Hs | molecular function | 199 | 9.93e-58 |
protein self-association | Hs | molecular function | 166 | 3.82e-47 |
transcription regulatory region DNA binding | Hs | molecular function | 199 | 9.93e-58 |
metal ion binding | Hs | molecular function | 199 | 9.93e-58 |
protein heterodimerization activity | Hs | molecular function | 166 | 3.82e-47 |
protein N-terminus binding | Hs | molecular function | 166 | 3.82e-47 |
WW domain binding | Hs | molecular function | 194 | 1.24e-55 |
chaperone binding | Hs | molecular function | 166 | 3.82e-47 |
protein phosphatase 2A binding | Hs | molecular function | 166 | 3.82e-47 |
MDM2/MDM4 family protein binding | Hs | molecular function | 199 | 9.93e-58 |
disordered domain specific binding | Hs | molecular function | 166 | 3.82e-47 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA binding | PANTHER | molecular function | 4.2E-115 |
transcription factor activity, sequence-specific DNA binding | PANTHER | molecular function | 4.2E-115 |
nucleus | PANTHER | cellular component | 4.2E-115 |
regulation of transcription, DNA-templated | PANTHER | biological process | 4.2E-115 |
apoptotic process | PANTHER | biological process | 4.2E-115 |
transcription regulatory region DNA binding | CDD | molecular function | 1.39327E-80 |
protein tetramerization | Gene3D | biological process | 1.1E-33 |