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CIS-REGULATION

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  1. Region 'REG00001572'

Cis-regulatory Region

Name

Cirobu.REG.Kh2012.C1:823069-823325|Nkxtun3

Short name

Cirobu.Nkxtun3-up9

Region ID

REG00001572

Status

Curated

Origin

natural region from C. robusta formely Ciona int. type A

Type of Activity

regulatory_region
(enhancer)

Author

Joshua F Coulcher (2023-02-22)

Annotator

Marion Gueroult-Bellone (2023-02-22)

Curator

Marion Gueroult-Bellone (2023-02-22)

View position in WashU

Description

Compared to its mother sequence, it lacks 65bp in 5'. Its activity is strongly reduced.

Hierarchy of Regulatory Regions

Modification of Cirobu.REG.Kh2012.C1:823069-823390|Nkxtun3 by deletion

Regulated gene(s)

KH2012:KH.C1.922 (BARHL1; BARHL2; TLX1)

Construct(s) made to test this region
n/a
Overview of functional TF binding sites in this region

823,069823,324

Motif Name Binding Factor(s) Sequence Position in Region Comment

Sequence

Aniseed Coordinates: [823,069 / 823,324] on scaffold KhC1

This 4754bp regulatory region is located upstream of Nkxtun3 (Nkxtun3-Up9) and is weakly active in ventral neurogenic midline and very weakly in dorsal neurogenic midline. Genomic coordinates are in the article.

Show sequence

Length: 256

AAGATGGCGGGCGCTTCTCATCTGGCTTGTTTGGCAACAATTGATCGATAGCCAAATCGC
ATTATGAGTCATAACTAAAATTCGAATGCGGGTGGTGAATTCGAACAAAAACGTCGCGCT
AACTCGACAGCACTATTGCGTCATAAAAAGTCGTAAAGGCGCGCGCTTAAACGAGTAATT
ACGGAAAAATTATGACATCGTTTAAATTTCCTACAACTGTTTACGTCGTAAGCGTCTCAT
TCATTGTGGGCGTTTA

Reference(s)

Coulcher et al. (2020). Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos. Elife 9():

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